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Dr. Longtao Huangfu, Ph.D.

Assistant Professor

Aug 2017 - Present

Peking University Cancer Hospital

Beijing

China

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  • Female-prevalent tumors, particularly gastrointestinal cancers, including gastric cancer, colorectal cancer, and esophageal cancer
  • Database-driven epidemiological analysis
  • Systems pharmacology research and novel drug development
  • Longtao Huangfu*, Huanbo Zhu*, Gangjian Wang*, Junbing Chen*, Yongqi Wang, Biao Fan, Xiaoyang Wang, Qian Yao, Ting Guo, Jing Han, Ying Hu, Hong Du, Xiaomei Li, Jiafu Ji, Xiaofang Xing. The deubiquitinase USP15 drives malignant progression of gastric cancer through glucose metabolism remodeling. Journal of Experimental & Clinical Cancer Research. 2024 Aug 20;43(1):235. doi: 10.1186/s13046-024-03152-2.
  • Longtao Huangfu*, Xiaoyang Wang*, Shanshan Tian, Junbing Chen, Xueying Wang, Biao Fan, Qian Yao, Gangjian Wang, Cong Chen, Jing Han, Xiaofang Xing, Jiafu Ji. Piceatannol enhances Beclin-1 activity to suppress tumor progression and its combination therapy strategy with everolimus in gastric cancer. Science China Life Sciences, 2023, 66(2):298-312. doi: 10.1007/s11427-022-2185-9.
  • Shanshan Tian*, Longtao Huangfu*, Sizhi Ai, Junwei Zheng, Le Shi, Wei Yan, Ximei Zhu, Qianwen Wang, Jiahui Deng, Yanping Bao, Suhua Chang and Lin Lu. Causal relationships between chronotype and risk of multiple cancers by using longitudinal data and mendelian randomization analysis. Science China Life Sciences, 2023, 66(10), 2433-2436. doi: 10.1007/s11427-022-2315-5.
  • Longtao Huangfu*, Biao Fan*, Gangjian Wang, Xuejun Gan, Shanshan Tian, Qifei He, Qian Yao, Jinyao Shi, Xiaomei Li, Hong Du, Xiangyu Gao, Xiaofang Xing, Jiafu Ji. Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer. Cell Death Discovery, 2022, 8(1): 5. doi: 10.1038/s41420-021-00802-8.
  • Longtao Huangfu, Qifei He, Jing Han, Jinyao Shi, Xiaomei Li, Xiaojing Cheng, Ting Guo, Hong Du, Wanhong Zhang, Xiangyu Gao, Fengming Luan, Xiaofang Xing, Jiafu Ji. MicroRNA-135b/CAMK2D Axis Contribute to Malignant Progression of Gastric Cancer through EMT Process Remodeling. International Journal of Biological Sciences, 2021,17(8):1940-1952. doi: 10.7150/ijbs.58062.
  • Qifei He*, Longtao Huangfu*, Biao Fan*, Qianzheng Zhuang, Liu He, Lin Li, Wei You, Xiaofang Xing. T-cells infiltration mediates the association between neutrophil/lymphocyte ratio and survival in gastric cancer. Cancer Medicine, 2023,12(15):15893-15902. doi: 10.1002/cam4.6228.
  • Gangjian Wang*, Longtao Huangfu*, Xiangyu Gao, Xuejun Gan, Xiaofang Xing, Jiafu Ji. A novel classification and scoring method based on immune-related transcription factor regulation patterns in gastric cancer. Frontiers in Oncology. 2022,12:887244. doi: 10.3389/fonc.2022.887244.
  • Shanshan Tian, Longtao Huangfu, Yanping Bao, Sizhi Ai, Suhua Chang, Qianwen Wang, Ximei Zhu, Wei Yan, Jie Shi, Le Shi, Jiahui Deng, Lin Lu. Causal associations of sleep traits with cancer incidence and mortality. Frontiers in Genetics. 2023,14:1309069. doi: 10.3389/fgene.2023.1309069.
  • Xiaoxiao Ma, Shuqin Jia, Gangjian Wang, Min Liang, Ting Guo, Hong Du, Sisi Li, Xiaomei Li, Longtao Huangfu, Jianping Guo, Xiaofang Xing, Jiafu Ji. TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance. Signal Transduction and Targeted Therapy. 2023,8(1):246. doi: 10.1038/s41392-023-01450-3.
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