Mini Review 10.5281/zenodo.19268993

Myofascial Pain Syndrome: Pathophysiology and Clinical Aspects

João Páscoa Pinheiro, Mariana Lourenço

Background: Myofascial pain syndrome (MPS) is a highly prevalent yet frequently underdiagnosed musculoskeletal condition associated with significant functional impairment. Its clinical complexity and the absence of objective biomarkers contribute to diagnostic…...

Case Report 10.5281/zenodo.19270372

Organ-Preserving Management of Primary Lynch Syndrome–Associated High-Grade Upper Tract Urothelial Carcinoma Using Gemcitabine–Cisplatin and Pembrolizumab: First Reported Case Worldwide

Aadhar Jain, Kinju Adhikari, Karthika Rani, et al.

Lynch syndrome (LS), caused by germline mismatch-repair mutations, increases the risk of upper tract urothelial carcinoma (UTUC), for which radical nephroureterectomy is the standard treatment. Non-surgical curative management has not been described previously. We report a 48-year-old man with…...

Systematic Review 10.5281/zenodo.19314058

Systematic Review on the Effectiveness of Anti-Embolism Stockings; A Need to Re-Evaluate the Evidence

Martyn J Parker, Mahmoud Awadallah, Sophie Easey, et al.

Objectives: To systematically review randomized controlled trials that have evaluated elasticated thrombo-embolic graduated compression stockings as prophylaxis of deep venous thrombosis in various health situations.

Design: Searches were carried out…...

Case Report 10.5281/zenodo.19309174

Severe Postpartum Thrombotic Microangiopathy Presenting with Purpura, Acute Kidney Injury, and Hepatic Dysfunction

Dr. Abinet Muluneh Wondimu

Background: Severe thrombocytopenia in the postpartum period is a life-threatening condition requiring urgent differentiation between thrombotic thrombocytopenic purpura (TTP), disseminated intravascular coagulation (DIC), and HELLP syndrome. Early recognition significantly…...

Case Report 10.5281/zenodo.19270688

Malignant Pleural Mesothelioma in Women: A Case Report

Nahidi M, Arfaoui H, Fazazi I, et al.

Pleural mesothelioma is a primary malignant tumor of the pleura whose origin is multifactorial. Exposure to asbestos in the home or at work is the main risk factor incriminated in the pathophysiology of pleural mesothelioma. Occupational exposure makes this pathology a notifiable disease.…...

Opinion 10.5281/zenodo.19115542

Prevalence of Musculoskeletal Injuries Among Recreational Gym Goers

A. Subash, Dr. M. Nisarudeen

Background: Recreational gym participation has increased rapidly due to growing awareness of fitness and healthy lifestyles. However, improper exercise techniques, inadequate supervision, overtraining, and poor warm-up practices may predispose gym users to musculoskeletal…...

Mini Review 10.5281/zenodo.19313851

Crime Scene Management: Principles, Practices, and Contemporary Challenges in Forensic Investigation

Dr. Vivek Chauhan

Crime scene management forms the cornerstone of forensic investigation, directly influencing the integrity, admissibility, and probative value of physical evidence. Improper scene handling can irreversibly compromise investigative outcomes. This narrative review discusses the theoretical…...

Case Report 10.5281/zenodo.19079618

Dual Cause of Recurrent Pregnancy Loss: Hashimoto's Thyroiditis and Inherited Protein S Deficiency

Salem Bouomrani, Wided Letaïef, Ines Masmoudi, et al.

Recurrent pregnancy loss (RPL) is a rare occurrence in routine medical practice complicating 1-3% of all pregnancies. They represent a real diagnostic challenge due to the multitude of possible etiologies, and remain unexplained in more than 50% of cases. We report the original observation of a…...

Case Report 10.5281/zenodo.19272123

Pleuropulmonary Staphylococcal Disease in Young Immunocompetent Man: A Case Report

Nahidi M, El Khattabi W, Arfaoui H, et al.

Staphylococcal pleuropulmonary disease (SPP) is an infectious pathology caused by Staphylococcus aureus, a germ responsible for a wide range of suppurative, toxigenic and multifocal infections (cutaneous, osteoarticular, pulmonary, etc.).

This entity is most often associated with…...