Letter to Editor 10.5281/zenodo.21852267

Air Pollution as a Risk Factor for Gestational Diabetes Mellitus: Time to Breathe this into Clinical Practice

Rahul Garg

The global burden of Gestational Diabetes Mellitus (GDM) continues to rise at an alarming pace, now complicating an estimated 14-25% of pregnancies worldwide [1]. While traditional risk factors - maternal obesity, advanced age, family history of type 2 diabetes - have long guided clinical…...

Research Article 10.5281/zenodo.21862008

Neuro-Mechanical Modeling and AI-Driven Exoskeleton Control for Rehabilitation Robotics: A Comprehensive Review

Mustafa M. Mansour

In recent years, rehabilitation robotics has become a promising area of research to enhance mobility and quality of life for people with neurological and musculoskeletal impairment. Lower-limb exoskeletons are one of the most promising advances in this field, combining advanced control…...

Research Article 10.5281/zenodo.21860443

Comparative Study of Modified Boey’s Score and Mannheim Peritonitis Index in Predicting Outcome of Perforated Peptic Ulcer with Diffuse Peritonitis

Adeel Asghar

Background: Perforated Peptic Ulcer (PPU) complicated with diffuse peritonitis despite all advances of diagnosis and surgical care. The timely and precise identification of prognosis is one of the most key issues to optimize peri-operative management. In this study, the Modified…...

Research Article 10.5281/zenodo.21862134

Anticonvulsant, Antioxidant, And In Vitro Cytotoxicity Activities of Leucaena leucocephala (Lam.) de Wit (Fabaceae) Leaf Methanol Extract

Cletus Anes Ukwubile, Amina Ismail Chinda, Anietie Eyo Robert, et al.

Although Leucaena leucocephala has long been used for its hepatoprotective, anticonvulsant, antioxidant, and anticancer properties, there has been no rigorous pharmacological validation. The anticonvulsant, antioxidant, and in vitro cytotoxic activities of L. leucocephala leaf methanol extract…...

Research Article 10.5281/zenodo.21852543

Clinico-Hematological Profile of Megaloblastic Anemia at a Tertiary Care Center in North India: A Cross-Sectional Study

Rahul Garg

Background: Megaloblastic anemia (MA) remains a prevalent yet underdiagnosed nutritional disorder in India, particularly among vegetarian populations. Despite its treatability, patients often present late with multisystem involvement.

Objective: To…...

Research Article 10.5281/zenodo.21860514

Pilot Study on the Relation Between Orthodox Spirituality, Inclusion and Health, In a Sample of Wheelchair Users

Konstantinos N. Papanikolaou

Persons with disabilities have significantly lower life expectancy compared to the general population. Concerning wheelchair users, the main causes of premature death are heart attack and cancer. The main risk factors are physical inactivity and obesity. Factors such as depression and social…...

Research Article 10.5281/zenodo.21860321

Machine Learning-Based Classification of Tuberculosis Using Whole-Blood Gene Expression Profiles: A Multi Cohort Transcriptomic Study with SHAP-Based Interpretability

Adeel Asghar

Background: Tuberculosis diagnosis remains a practical challenge in high-burden settings, where available tests have well-known limitations around sensitivity, cost, and turnaround time. Whole blood gene expression profiling offers a non-sputum-based alternative approach, but…...

Research Article 10.5281/zenodo.21860752

Testing the Limits: Can Federated EHR Networks Detect Teratogenic Signals?

Fady Tawfik, Justyna Sienkianiec, Mrinalini Deverapalli, et al.

Background: First-trimester topiramate exposure carries an approximately 2-fold increased risk of Major Congenital Malformations (MCMs) compared with levetiracetam, which has among the lowest MCM rates of Anti-Seizure Medications (ASMs). Federated Electronic Health Record (EHR)…...

Perspective 10.5281/zenodo.21861636

Reflections from the Filthy Mud: Environmental Wisdom and Coastal Pollution in Industrial Corridors

Chee Kong Yap

This paper is a reflective synthesis of long-term environmental monitoring and personal experience from two of Malaysia’s most polluted coastal ecosystems: Kuala Juru in Penang and Kg. Pasir Puteh in Southern Johore. Drawing upon empirical evidence collected in 2004 and 2005 on elevated levels…...