Research Article 10.5281/zenodo.19653522

Impact of Exclusive Cannabis Use on Lung Function and Asthma Control: A Comparative Retrospective Study

Nahidi M, Bamha H, El Khattabi W, et al.

This retrospective study evaluates the respiratory impact of exclusive cannabis use via traditional pipes in asthmatic patients (n=7) compared to a non-smoking control group (n=54) to assess the clinical and functional consequences of this practice. The results demonstrate increased morbidity…...

Review Article 10.5281/zenodo.19652606

Synthetic Biology: Paradigm Revolution or Philosophical Eclipse? From Bacillus subtilis Genomics to Direct Design

Max Roberto Batista de Araújo, Genrikh Ashniev, Rhayane Cristina Viegas Santos, et al.

Synthetic biology represents a profound transformation in the life sciences, shifting from reactive genetic manipulation to proactive, design-driven construction of biological systems. Using Bacillus subtilis genomics as a historical anchor, we trace the conceptual trajectory from genetic…...

Research Article 10.5281/zenodo.19965382

Auditory Pathologies in Children with Cerebral Palsy

Mohammed Radef Dawood, Rasha Sabri Radef

Background: The location of lesions causing hearing loss in patients with cerebral palsy remains unclear.

Objectives: To evaluate the incidence and characteristics of auditory pathologies in children with various forms of cerebral…...

Research Article 10.5281/zenodo.19953359

Advanced Flight Control Systems: Integration of Pixhawk Pilot Support Package and 6-DOF Dynamic Modeling

Mahabub Sultan

This report presents a comprehensive study on the implementation and simulation of advanced flight control systems for Unmanned Aerial Vehicles (UAVs). The work is divided into two primary domains: the practical application of the Pixhawk Pilot Support Package (PSP) within the MATLAB/Simulink…...

Perspective 10.5281/zenodo.19765318

Six Years on: Persistent Structural Gaps in COVID-19 Pandemic Policy and Implications for Future Global Health Crises

Malik Sallam

Six years after the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) as a global pandemic, several key scientific and policy questions remain unresolved— an unsettling state of affairs given the inevitability of future pandemics. This Perspective examines five domains…...

Research Article 10.5281/zenodo.19673700

Clinical Phenotypes and Lung Function Patterns in Severe Asthma

Nahidi M, Bamha H, El Khattabi W, et al.

Conducted on a cohort of 150 patients followed at the Respiratory Diseases Department of the 20 August 1953 Hospital in Casablanca between 2019 and 2023, this retrospective and analytical study outlines the profile of severe asthma in a Moroccan referral center. The study population has a mean…...

Review Article 10.5281/zenodo.19948448

Aloe-Emodin and Emodin's Role in Premalignant Lesions of the Oral Cavity Cancers and Other Organs

Abhijit G. Banerjee, Gargi Roy Goswami, Tapas Mukherjee

Oral squamous cell carcinoma (OSCC) is one of the commonest cancers globally. Prevalence of the disease is high in the third world countries of South-east Asia, specifically tied to inherent abuse of tobacco and areca nuts. The disease manifests as oral potentially malignant disorders, such as…...

Review Article 10.5281/zenodo.19943655

Digital Assets: A New Path for Financial Innovation and Consumer Protection

Shungui Xiang, Yin Tang, Jun Zhang

With the rapid development of the digital economy, digital assets have gradually become an important driving force for the transformation of the financial system. Based on technologies such as Blockchain, digital assets have played a significant role in improving financial efficiency, promoting…...

Research Article 10.5281/zenodo.19763230

Continuous - Time Markov Modeling of Durvalumab Dynamics after Chemoradiotherapy in Stage III NSCLC (PACIFIC Era): Development, Validation, and Extrapolation

Zurita AJW, Ruíz MAG, Carmona DM, et al.

Background: Immunotherapy in un-resectable stage III NSCLC shows delayed treatment effects and time-varying hazards that challenge proportional-hazards assumptions. We developed a Continuous-Time Markov Chain (CTMC) model - with piecewise hazards - to capture the temporal…...