Dr. Hossein Hosseinkhani, Biomedical Engineer, has broad experience in life sciences and is an expert in nanotechnology, biomaterials, drug delivery, 3D in vitro systems, bioreactor technology, and bioengineering stem cells technology. His working experience is mainly attributed to academia and industry of biomedical engineering research and development (which includes several years of basic science research experience in a number of premier institutions related to the structure and function of biomaterials, and in polymer-based and mineral-based medical implants development in the medical device industry). He has been awarded several prestigious awards including JSPS (Japan Society for Promotion of Science) Award, European Marie Skłodowska-Curie Award, and Japanese ICYS (International Center for Young Scientists) Award. He authored more than 100 scientific papers published on peer-reviewed Journals, 4 books, and 10 book chapters (H-index: 51 Google Scholar). He is inventor of 16 National and International patents, several of which are licensed to companies acting in the biomedical fields and translated to 7 commercial products. He is the founder of Matrix HT, Inc., a world leading Biotech Company dedicated to healthcare technology to improve patient's quality of life. He is Editor-in-Chief of Recent Progress in Materials, a peer-reviewed Open Access journal published online by LIDSEN Publishing Inc., Editor-in-Chief of Journal of Modern Nanotechnology, a peer-reviewed Open Access journal published online by the Innovation Forever Publishing Group Ltd., Editor-in-Chief of Biomedical Science and Clinical Research, a peer-reviewed Open Access journal published online by Opast Publishing Group, Associate Editor of Polymer for Advanced Technology, a peer-reviewed journal published by Wiley, and the Country Editor of Current Drug Delivery.

• Biomedical Engineering
• Biosensors
• Drug Delivery Systems
• Nanotechnology and Tissue Engineering

• H. Hosseinkhani*, A.J. Domb, "Nanomaterials in Therapeutic Technology", Biomaterials, in preparation (2024) (SCI; JCR 2021 IF = 12.479).
• H. Hosseinkhani*, "Viral/Non-Viral Vectors in DNA/RNA Delivery Technology", Recent Progress in Materials, 6, 027 (2024).
• F. Abedini, M. Ebrahimi, A.J. Domb, H. Hosseinkhani*, "Alginate/Chitosan Nanoparticles as Drug Delivery Vehicles for Pseudocerastes Persicus Snake Venom", International Journal of Molecular Sciences, in preparation (2024) (SCI; JCR 2021 IF = 6.208).
• H. Hosseinkhani*, A.J. Domb, G. Sharifzadeh, V. Nahum, "Gene Therapy for Regenerative Medicine", Pharmaceutics, 15, 856-896 (2023) (SCI; JCR 2021 IF = 6.525). cited: 26
• H. Hosseinkhani*, "Potential Application of Nanomedicine", Recent Progress in Materials, 5, 1-15 (2023).
• H. Hosseinkhani*, "Developing 3D Technology for Drug Discovery", Current Drug Delivery, 19, 813-814 (2022) (SCI; JCR 2021 IF = 3.758). cited: 1
• S. Khalaji, N.G. Ebrahimi, H. Hosseinkhani, "Enhancement of biocompatibility of PVA/HTCC blend polymer with collagen for skin care application", International Journal of Polymeric Materials and Polymeric Biomaterials, 70, 459-468 (2021) (SCI; JCR 2021 IF = 2.604).cited: 46
• A.J. Domb, G. Sharifzadeh, V. Nahum, H. Hosseinkhani*, "Safety Evaluation of Nanotechnology Products", Pharmaceutics, 13, 1615 (2021) (SCI; JCR 2021 IF = 6.525).cited: 26
• Diana Ickowicz, A.J. Domb, H. Hosseinkhani*, "Theragnostic positively charged Magnetic Nanoparticles", International Journal of Nanotechnology and Application, 11 (2), 1-10 (2021) (SCI; JCR 2021 IF = 6.1093).
• N.Y. Steinman, L.M. Campos, Y. Feng, A.J. Domb, H. Hosseinkhani, "Cyclopropenium nanoparticles and gene transfection in cells", Pharmaceutics, 12, 768-779 (2020) (SCI; JCR 2021 IF = 6.525). cited: 10
• H. Hosseinkhani*, "siRNA Delivery Systems in Cancer Therapy", Organic & Medicinal Chemistry International Journal, 10 (1), 1-3 (2020) (SCI; JCR 2021 IF = 1.218).
• H. Hosseinkhani*, A.J. Domb "Biodegradable polymers in gene-silencing technology", Polymers For Advanced Technologies, 30, 2647-2655 (2019) (SCI; JCR 2021 IF = 3.665). cited: 32
• V. Hosseini, N.F. Maroufi, S. Saghati, N. Asadi, M. Darabi, S. Nazari Soltan Ahmad, H. Hosseinkhani, R. Rahbarghazi, "Current progress in hepatic tissue regeneration by tissue engineering", Journal of Translational Medicine, 17(1), 383 (2019) (SCI; JCR 2017 IF = 4.197).
• S. Toosi, H. Naderi-Meshkin, F. Kalalinia, H. Hosseinkhani, A. Heirani-Tabasi, S. Havakhah, S. Nekooei, A.H. Jafarian, F. Rezaie, M. Taghi Peivandi, H. Mesgarani, J. Behravan, "Bone defect healing is induced by collagen sponge/polyglycolic acid", Journal of Materials Science: Materials in Medicine 30 (3), 33 (2019) (SCI; JCR 2021 IF = 3.896). cited: 45
• N. Ebrahimi, A.A. Soleimani, J. Rashidiani, B. Malekafzali, F. Abedini, H. Hosseinkhani, " Chitosan/Fluoride Nanoparticles for Preventing Dental Caries", Current Dentistry, 1, 61-67 (2019). cited: 10
• F. Karimi Dermani, F. Azizi Jalilian, H. Hossienkhani, R. Ezati, R. Amini, "siRNA Delivery Technology for Cancer Therapy: Promise and Challenges", Acta Medica Iranica, 57, 83-94 (2019). cited: 10
• F. Abedini, M. Ebrahimi, A.H. Roozbehani, A.J. Domb, H. Hosseinkhani*, "Overview on Natural Hydrophilic Polysaccharide Polymers in Drug Delivery", Polymers For Advanced Technologies, 29, 2564-2573 (2018) (SCI; JCR 2021 IF = 3.665). cited: 70
• S. Saberianpour, M. Heidarzadeh, M.H. Geranmayeh, H. Hosseinkhani, R. Rahbarghazi, M. Nouri, "Tissue engineering strategies for the induction of angiogenesis using biomaterials", Journal of Biological Engineering, 12, 1-15 (2018) (SCI; JCR 2021 IF = 4.365). cited: 72
• F. Abedini, M. Ebrahimi, H. Hosseinkhani*, "Technology of RNA Interference in advanced medicine", MicroRNA, 7, 74-84 (2018). cited: 25
• H. Hosseinkhani*, "3-D culture systems for cell culture technology", Journal of Cell Research, 1, 1-4 (2018).
• G. Sharifzadeh, H. Hosseinkhani*, "Biomolecule-Responsive Hydrogels in Medicine", Advanced Healthcare Materials, 6, 1-35 (2017) (SCI; JCR 2021 IF = 9.333). cited: 110
• F. Mottaghitalab, A. Rastegari, M. Farokhi, R. Dinarvand, H. Hosseinkhani, K.L. Ou, D. W. Pack, C. Mao, M. Dinarvand, Y. Fatahi, F. Atyabi, "Prospects of siRNA applications in regenerative medicine", International Journal of Pharmaceutics, 524, 312-329 (2017) (SCI; JCR 2021 IF = 5.875). cited: 18
• M. Ghadiri, E. Vasheghani-Farahani, F. Atyabi, F. Kobarfard, F. Mohamadyar-Toupkanlou, H. Hosseinkhani, "Transferrin-Conjugated Magnetic Dextran-Spermine Nanoparticles for Targeted Drug Transport across Blood-Brain Barrier", Journal of Biomedical Materials Research Part A, 105, 2851-2864 (2017) (SCI; JCR 2021 IF = 4.396). cited: 72
• M. Shahrezaei, S. Habibzadeh, A.A. Babaluo, H. Hosseinkhani, M. Haghighi, A. Hasanzadeh, R. Tahmasebpour "Study of synthesis parameters and photocatalytic activity of TiO2 nanostructures", Journal of Experimental Nanoscience, 12, 45-61 (2017) (SCI; JCR 2021 IF = 3.075). cited: 31
• S. Toosi, H. Naderi-Meshkin, F. Kalalinia, M.T. Peivandi, H. Hosseinkhani, A.R. Bahrami, A. Heirani-Tabasi, M. Mirahmadi, J. Behravan "Long bone mesenchymal stem cells (Lb-MSCs): clinically reliable cells for osteo-diseases", Cell and Tissue Banking, 18, 489–500 (2017) (SCI; JCR 2021 IF = 1.522). cited: 16
• M. Ghadiri, E. Vasheghani-Farahani, F. Atyabi, F. Kobarfard, H. Hosseinkhani, "In-Vitro Assessment of Magnetic Dextran-Spermine Nanoparticles for Capecitabine Delivery to Cancerous Cells",  Iranian Journal of Pharmaceutical Research, 16, 1320-1334 (2017) (SCI; JCR 2021 IF = 1.696). cited: 16
• N. Abassi, S. M. Hashemei, M. Salehi, H. Jahani, S. J. Mowla, M. Soleimani, H. Hosseinkhani*, "Influence of oriented nanofibrous PCL scaffolds on quantitative gene expression during neural differentiation of mouse embryonic stem cells", Journal of Biomedical Materials Research Part A, 104, 155-164 (2016) (SCI; JCR 2021 IF = 4.396). cited: 38
• M. Farokhi, F. Mottaghitalab, M.A. Shokrghozar, K.L. Ou, C. Mao, H. Hosseinkhani, "Importance of dual delivery systems for bone tissue engineering", Journal of Controlled Release, 225, 152-169 (2016) (SCI; JCR 2021 IF = 11.47). cited: 138.
• M.B. Gholivand, L. Mohammadi-Behzad, H. Hosseinkhani, "Application of Cu-chitosan/multi-walled carbon nanotube film modified electrode for the sensitive determination of rutin", Analytical Biochemistry, 493, 35-43 (2016) (SCI; JCR 2021 IF = 3.365). cited: 64
• M. Alibolandi, K. Abnous, F. Sadeghi, M. Ramezani, H. Hosseinkhani, F. Hadizadeh, "Folate Receptor-Targeted Multimodal Polymersomes for delivery of quantum dots and doxorubicin to breast adenocarcinoma: in vitro and in vivo Evaluation", International Journal of Pharmaceutics, 500, 162-178 (2016) (SCI; JCR 2021 IF = 5.875). cited: 104
• S. Toosi, H. Naderi-Meshkin, F. Kalalinia, M.T. Peivandi, H. Hosseinkhani, A.R. Bahrami, A. Heirani-Tabasi, M. Mirahmadi, J. Behravan "PLGA-incorporated collagen: Toward a Biodegradable Composite Scaffold for Bone-tissue Engineering ", Journal of Biomedical Materials Research Part A, 104, 2020-2028 (2016) (SCI; JCR 2021 IF = 4.396). cited: 53
• S. Toosi, H. Naderi-Meshkin, F. Kalalinia, M.T. Peivandi, H. Hosseinkhani, A.R. Bahrami, A. Heirani-Tabasi, M. Mirahmadi, J. Behravan "Comparative characteristics of mesenchymal stem cells derived from reamer-irrigator-aspirator, iliac crest bone marrow, and adipose tissue", Cellular and Molecular Biology, 62, 68-74 (2016) (SCI; JCR 2021 IF = 1.77). cited: 21
• F. Mottaghitalab, M.A. Shokrghozar, M. Farokhi, H. Hosseinkhani, "Silk fibrin nanoparticles as novel drug delivery systems", Journal of Controlled Release, 206, 161-176 (2015) (SCI; JCR 2021 IF = 11.47). cited: 265
• F. Mottaghitalab, H. Hosseinkhani, M.A. Shokrghozar, C. Mao, M. Farokhi, "Silk as potential candidate for bone tissue engineering ", Journal of Controlled Release, 215, 112-128 (2015) (SCI; JCR 2021 IF = 11.47). cited: 133
• S.M. Seyedpour, M. Pachenari, M. Janmaleki, M. Alizadeh, H. Hosseinkhani, "Effects of Antimitotic Drug on Mechanical Behaviors of Cytoskeleton in Distinct Grades of Colon Cancer Cell Lines, Journal of Biomechanics, 48, 1172-1178(2015) (SCI; JCR 2021 IF = 2.712).cited: 22
• H.C. Han, H.C. Lo, K.H. Chen, L.C. Chen, K.L. Ou, H. Hosseinkhani*, "Nano-textured fluidic biochip as biological filter for selective survival of cells and biological microorganisms", Journal of Biomedical Materials Research Part A, 103, 2015-2023 (2015) (SCI; JCR 2021 IF = 4.396). cited: 10
• H. Jahani, F. Azizi Jalilian, S. Kaviani, M. Soleimani, N. Abassi, H. Hosseinkhani*, "Controlled surface morphology and hydrophilicity of polycaprolactone towards differentiation of mesenchymal stem cells into neural cells ", Journal of Biomedical Materials Research Part A, 103, 1875-1881 (2015) (SCI; JCR 2021 IF = 4.396). cited: 54
• H. Hosseinkhani*, F. Abedini, K.L. Ou, A.J. Domb, "Polymers in Gene Therapy Technology", Polymers For Advanced Technologies, 26, 198-211 (2015) (SCI; JCR 2021 IF = 3.665). cited: 44
• N. Baheiraei, M. Azami, H. Hosseinkhani, "Investigation of Magnesium incorporation within gelatin/calcium phosphate nanocomposite scaffold for bone tissue engineering", International Journal of Applied Ceramic Technology, 12, 245-253 (2015)(SCI; JCR 2021 IF = 1.968).cited: 16
• A. Jain, H. Hosseinkhani, A.J. Domb, W. Khan, "Cationic Polymers for the Delivery of Therapeutic Nucleotides", Polysaccharides: Bioactivity and Biotechnology, 1969-1990 (2015).
• M. Pachenari, M. Seyedpour, S. Babazadeh Shayan, S. Taranejoo, M. Janmaleki, H. Hosseinkhani, "Mechanical properties of cancer cytoskeleton depend on actin filaments to microtubules content: Investigating different grades of colon cancer cell lines", Journal of Biomechanics, 47, 373-379 (2014) (SCI; JCR 2021 IF = 2.712). cited: 38
• R Rahbarghazi, SM Nassiri, SH Ahmadi, E Mohammadi, S Rabbani, A. Araghi, H. Hosseinkhani, "Dynamic induction of pro-angiogenic milieu after transplantation of marrow-derived mesenchymal stem cells in experimental myocardial infarction", International Journal of Cardiology, 173, 453-466 (2014) (SCI; JCR 2021 IF = 4.164). cited: 78
• W.Y. Yeo, H. Hosseinkhani, S.A. Rahman, R. Rosli, A.J. Domb, S. Abdullah, "Safety Profile of Dextran-Spermine Gene Delivery Vector in Mouse Lungs", Journal of Nanoscience and Nanotechnology, 14, 3328-3336 (2014) (SCI; JCR 2021 IF = 1.134). cited: 26
• M. Alibolandi, K. Abnous, M. Ramezani, H. Hosseinkhani, F. Hadizadeh "Synthesis of AS1411-Aptamer-Conjugated CdTe Quantum Dots with High Fluorescence Strength for Probe Labeling Tumor Cells", Journal of Fluorescence, 24, 1519-1529 (2014) (SCI; JCR 2021 IF = 2.217). cited: 51
• A. Ghodsizadeh, H. Hosseinkhani, A. Piryaei, B. Pournasr, M. Najarasl, Y. Hiraoka, H. Baharvand, "Galactosylated Collagen Matrix Enhanced In vitro Maturation of Human Embryonic Stem Cell-derived Hepatocyte-like Cells", Biotechnology Letters, 36, 1095-1106 (2014) (SCI; JCR 2021 IF = 2.461). cited: 21
• D. Shi, R. Tatu, Q. Liu, H. Hosseinkhani, "Stem Cells Based Tissue Engineering for Regenerative Medicine ", Nano LIFE, 4 (2) 1-13 (2014) (SCI; JCR 2021 IF = 0.7). cited: 5
• W. He, H. Hosseinkhani*, R. Mohammadinejad, Z. Roveimiab, D.Y. Hueng, K.L. Ou, A.J. Domb, "Polymeric Nanoparticles for Therapy and Imaging", Polymers For Advanced Technologies, 25, 1216-1225 (2014) (SCI; JCR 2021 IF = 3.665). cited: 27
• C.S. Hu, S.L. Tang, C.H. Chiang, H. Hosseinkhani, P.D. Hong, M.K Yeh, "Characterization and antitumor effects of chondroitin sulfate-chitosan nanoparticles delivery system", Journal of Nanoparticle Research, 16, 1-15 (2014) (SCI; JCR 2021 IF = 2.252). cited: 27.
• K.L. Ou, H. Hosseinkhani* "Development of 3D in vitro Technology for Medical Applications", International Journal of Molecular Sciences, 15, 17938-17962 (2014) (SCI; JCR 2021 IF = 6.208). cited: 99
• K.L. Ou, J.S. Chu, H. Hosseinkhani, J.F. Chiou, C.H. Yu, "Biomedical nanostructured coating for minimally invasive surgery devices applications: characterization, cell cytotoxicity evaluation and an animal study in rat", Surgical Endoscopy, 28: 2174-2188 (2014) (SCI; JCR 2021 IF = 4.584). cited: 35
• C.F. Huang, C.F. Huang, H.J. Chiang, H.J. Lin, H. Hosseinkhani, K.L. Ou, P.W. Peng, "Comparison of Cell Response and Surface Characteristics on Titanium Implant with SLA and SLAffinity Functionalization", Journal of Electrochemical Society, 161, 15-20 (2014) (SCI; JCR 2021 IF = 4.316). cited: 25
• H. Hosseinkhani*, P.D. Hong, D.S. Yu, "Self-assembled Proteins and Peptides for Regenerative Medicine", Chemical Reviews, 113, 4837-4861 (2013) (SCI; JCR 2021 IF = 72.087). cited: 253
• H. Hosseinkhani*, Y.R. Chen, W. He, P.D. Hong, D.S. Yu, A.J. Domb, "Engineering of Magnetic DNA Nanoparticles for Tumor-Targeted Therapy", Journal of Nanoparticle Research, 15, 1345-1355 (2013) (SCI; JCR 2021 IF = 2.253). cited: 26
• H. Hosseinkhani*, Y. Hiraoka, C.H. Li, Y.R. Chen, D.S. Yu, P.D. Hong, K.L. Ou, "Engineering Three-Dimensional Collagen-IKVAV Matrix to Mimic Neural Microenvironment", ACS Chemical Neuroscience, 4,1229-35 (2013) (SCI; JCR 2021 IF = 4.418). cited: 93
• H. Hosseinkhani*, W.J. He, C.H. Chiang, D.S. Yu, P.D. Hong, A.J. Domb, K.L. Ou "Biodegradable Nanoparticles for Gene Therapy Technology", Journal of Nanoparticle Research, 15, 1794-1809 (2013) (SCI; JCR 2021 IF = 2.253). cited: 40
• R. Amini, F. Azizi Jalilian, S. Abdullah, A. Veerakumarasivam, H. Hosseinkhani, A.S. Abdulamir, A .J. Domb, D. Ickowicz, R. Rosli, "Dynamics of PEGylated-Dextran-Spermine Nanoparticles for Gene Delivery to Leukemic Cells", Applied biochemistry and biotechnology, 170, 841-853, (2013) (SCI; JCR 2021 IF = 2.431). cited: 25
• W.-J. He, H. Hosseinkhani*, P.-D. Hong, C.-H. Chiang, D.-S., Yu, "Magnetic Nanoparticles for Imaging Technology ", International Journal of Nanotechnology, 10, 930-944 (2013) (SCI; JCR 2021 IF = 1.02). cited: 22
• C.-H. Chiang, H. Hosseinkhani, W.-S. Cheng, C.-W. Chen, C.-H. Wang, Y.-L. Lo, "Improving drug loading efficiency and delivery performance of micro- and nanoparticle preparations through optimizing formulation variables", International Journal of Nanotechnology, 10, 996-1006 (2013) (SCI; JCR 2021 IF = 1.02). cited: 12
• S.-F. Ou, C.-S. Chen, H. Hosseinkhani, C.-H. Yu, Y.-D. Shen, K.-L. Ou, "Surface properties of nano-structural silicon-doped carbon films for biomedical applications", International Journal of Nanotechnology, 10, 945-958 (2013) (SCI; JCR 2021 IF = 1.02). cited: 17
• H. Hosseinkhani*, K.H. Chen "Editorial: Nanotechnology Research in Taiwan", International Journal of Nanotechnology, 10, 837-839 (2013) (SCI; JCR 2021 IF = 1.02). cited: 1
• H. Hosseinkhani*, P.D. Hong, D.S. Yu, Y.R. Chen, I.V. Farber, A.J. Domb, "Development of 3D in vitro platform technology to engineer mesenchymal stem cells", International Journal of Nanomedicine, 7, 3035-3043 (2012) (SCI; JCR 2018 IF = 4.471). cited: 45
• W. Khan, H. Hosseinkhani, D. Ickowicz, P.D. Hong, D.S. Yu, A.J. Domb, "Polysaccharide Gene Transfection Agents", Acta Biomaterialia, 8, 4224-4232 (2012) (SCI; JCR 2020 IF = 8.974). cited: 106
• F. Abedini, H. Hosseinkhani, M. Ismail, A.J. Domb, A.R. Omar, C. Pei Pei, P.D. Hong, D.S. Yu, I.V. Farber, "Cationized Dextran Nanoparticles-Encapsulated CXCR4-siRNA Enhanced Correlation between CXCR4 Expression and Serum ALP in Colorectal Cancer", International Journal of Nanomedicine, 7, 4159-4168 (2012) (SCI; JCR 2018 IF = 4.471). cited: 59
• K. Subramani, S. Pathak, H. Hosseinkhani, "Recent trend in diabetes treatment using nanotechnology", Digest Journal of Nanomaterials and Biostructures, 7, 85-95 (2012) (SCI; JCR 2021 IF = 0.87). cited: 63
• H. Hosseinkhani*, "3D in vitro technology for drug discovery", Current Drug Safety, 7, 37-43 (2012). (SCI; JCR 2021 IF = 1.22). cited: 24
• M. Mohammad-Taheri, E. Vasheghani-Farahani, H. Hosseinkhani, S.A. Shojaosadati, M. Soleimani, "Fabrication and characterization of a new MRI contrast agent based on a magnetic dextran-spermine nanoparticle system", Iranian Polymer Journal, 21, 239-251 (2012) (SCI; JCR 2020 IF = 1.899). cited: 25
• R. Amini, H. Hosseinkhani, A.S. Abduamir, R. Rosli, F.A. Jalilian, "Engineered Smart Biomaterials for Gene Delivery ", Gene Therapy and Molecular Biology, 14, 72-86 (2012) (SCI; JCR 2013 IF = 0.429). cited: 11
• M. Mahmoudi, H. Hosseinkhani, M. Hosseinkhani, S. Boutry, A. Simchi, W. S. Journeay, K. Subramani, S. Laurent, "Magnetic Resonance Imaging Tracking of Stem Cells in Vivo Using Iron Oxide Nanoparticles as a Tool for the Advancement of Clinical Regenerative Medicine", Chemical Reviews, 111, 253-280 (2011) (SCI; JCR 2021 IF = 72.087). cited: 421
• H. Hosseinkhani*, "Editorial: On Nanomedicine", International Journal of Nanotechnology, 8, 615-617 (2011) (SCI; JCR 2021 IF = 1.02). cited: 5
• H. Hosseinkhani*, M. Hosseinkhani, Y.R. Chen, K. Subramani, A.J. Domb, "Innovative technology of engineering magnetic DNA nanoparticles for gene therapy", International Journal of Nanotechnology, 8, 724-735 (2011) (SCI; JCR 2021 IF = 1.02). cited: 15
• M. Hosseinkhani, H. Hosseinkhani*, Y.R. Chen, K. Subramani, "In vitro physicochemical evaluation of DNA nanoparticles", International Journal of Nanotechnology, 8, 736-748 (2011) (SCI; JCR 2021 IF = 1.02). cited: 12
• F. Abedini, H. Hosseinkhani, M. Ismail, Y.R. Chen, A.R. Omar, C. Pei Pei, A.J. Domb, "In vitro intracellular trafficking of biodegradable nanoparticles of dextran-spermine in cancer cell lines", International Journal of Nanotechnology, 8, 712-723 (2011) (SCI; JCR 2021 IF = 1.02). cited: 24
• R.S. Sarabi, E. Sadeghi, H. Hosseinkhani, M. Mahmoudi, M. Kalantari, M. Adeli, "Polyrotaxane Capped Quantum Dots as New Candidates for Cancer Diagnosis and Therapy", Journal of Nanostructured Polymers and Nanocomposites, 7, 18-31 (2011) (SCI; JCR 2014 IF = 3.471). cited: 12
• K. Subramani, R. Mathew, H. Hosseinkhani, M. Hosseinkhani, "Bone regeneration around dental implants as a treatment for peri-implantitis: A review of the literature", Journal of Biomimetics, Biomaterials & Tissue Engineering, 11, 21-33 (2011). (SCI; JCR 2021 IF = 0.81). cited: 12
• H.R. Kalhor, F. Shahin V, M.H. Fouani, H. Hosseinkhani, "Self-Assembly of Tissue Transglutaminase into Amyloid-Like Fibrils Using Physiological Concentration of Ca2+", Langmuir, 27, 10766-10784 (2011) (SCI; JCR 2021 IF = 3.882), cited: 13
• F. Abedini, M. Ismail, H. Hosseinkhani, T.I. Azmi, A.R. Omar, C. Pei Pei, M.H. Bejo, A.J. Domb, "Effects of CXCR4 siRNAs/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver", Cancer Management and Research, 3, 301-309 (2011). (SCI; JCR 2019 IF = 2.886). cited: 45
• H. Hosseinkhani*, M. Hosseinkhani, S. Hattori, R. Matsuoka, N. Kawaguchi, "Micro and nanoscale in vitro 3D culture system for cardiac stem cells", Journal of Biomedical Materials Research Part A, 94, 1-8 (2010) (SCI; JCR 2021 IF = 4.396), cited: 126
• S. Mohageri, H. Hosseinkhani, N.G. Ebrahimi, M. Solimani, A.M. Kajbafzadeh, "Proliferation and differentiation of mesenchymal stem cell on collagen sponge reinforced with polypropylene/polyethylene terephathalate blend fibers", Tissue Engineering Part A, 16, 3821-3830 (2010) (SCI; JCR 2020 IF = 3.845), cited: 70
• S. Lindstrom, A. Iles, J. Persson, H. Hosseinkhani, M. Hosseinkhani, A. Khademhosseini, H. Lindstrom, H. Andersson, "Nanoporous Titania Coating of Microwell Chips for Stem Cell Culture and Analysis", Journal of Biomechanical Science and Engineering, 5, 272-279 (2010) (SCI; JCR 2021 IF = 0.80), cited: 25
• S. Abdullah, W.Y. Yeo, H. Hosseinkhani, M. Hosseinkhani, E. Masrawa, R. Ramasamy, R. Rosli, S.A. Rahman, A.J. Domb, "Gene Transfer into the Lung by Nanoparticle Dextran-Spermine/Plasmid DNA Complexes", Journal of Biomedicine and Biotechnology, 2010, 1-10 (2010) (SCI; JCR 2017 IF = 2.583), cited: 46
• F. Abedini, M. Ismail, H. Hosseinkhani, T. Azmi, A. Omarb, C. PeiPei, N. Ismail, I.Y. Farber, A.J. Domb, "Toxicity evaluation of dextran-spermine polycation as a tool for gene therapy in vitro", Journal of Cell and Animal Biology, 4, 170-176 (2010). (SCI; JCR 2019 IF = 0.907). cited: 22
• R Amini, R Rosli, S Abdullah, H Hosseinkhani, A Veerakumarasivam, "Delivery of Plasmid Expressing Green Fluorescent Protein by PEGylated Dextran-Spermine to Acute Myeloid Leukemic Cells", Med J Malaysia, 2010; 65: 118-120 (2010). cited: 1
• A. Balbarini, A. Magera, M.C. Barsotti, H. Hosseinkhani, F. Chiellini, R. Solaro, R. Di Stefano, "SELF ASSEMBLING PEPTIDE AMPHIPHILE NANOFIBERS AS A SCAFFOLD FOR ENDOTHELIAL PROGENITOR CELLS", Journal of the American College of Cardiology, 55, E1652, (2010). (SCI; JCR 2020 IF = 24.09). cited: 1
• K. Subramani, H. Hosseinkhani, A. Khraisat, M. Hosseinkhani, Y. Pathak, "Targeting nanoparticles as drug delivery systems for cancer treatment", Current Nanoscience, 5, 134-140 (2009) (SCI; JCR 2021 IF = 1.52), cited: 89
• H. Hosseinkhani*, M. Hosseinkhani, "Biodegradable polymer-metal complexes for gene and drug delivery", Current Drug Safety, 4, 79-83 (2009). (SCI; JCR 2021 IF = 1.22). cited: 62
• H. Hosseinkhani*, M. Hosseinkhani, E. Vasheghani, M. Nekoomanesh, "In vitro sustained release and degradation study of biodegradable poly (D,L-lactic acid) microspheres loading theophylline", Advanced Science Letters, 2, 70-77 (2009) (SCI; JCR 2021 IF = 0.1), cited: 14
• R Di Stefano, MC Barsotti, A Magera, H Hosseinkhani, F Chiellini, D Dinucci, M Alderighi, R Solaro, A Balbarini, "A biological self assembling amphiphilic peptide enhances Endothelial Progenitor Cells growth and paracrine release", EUROPEAN HEART JOURNAL, 30, 177-177 (2009). (SCI; JCR 2020 IF = 29.98). cited: 1
• F. Tian, H. Hosseinkhani, M. Hosseinkhani, A. Khademhosseini, Y. Yokoyama, G. Estrada, H. Kobayashi, "Quantitative analytical of cell adhesion on aligned micro- and nanofibers", Journal of Biomedical Materials Research Part A, 84, 291-299 (2008) (SCI; JCR 2021 IF = 4.396). cited:195
• H. Hosseinkhani*, M. Hosseinkhani, A. Khademhosseini, N. P. Gabrielson, D.W. Pack, H. Kobayashi, "DNA nanoparticles encapsulated in 3-D tissue engineered scaffold enhance osteogenic differentiation of mesenchymal stem cells", Journal of Biomedical Materials Research Part A, 85, 47-60 (2008) (SCI; JCR 2021 IF = 4.396), cited:141
• H. Hosseinkhani*, M. Hosseinkhani, "Suppression effect of basic fibroblast growth factor on mesenchymal stem cell proliferation activity; Part I: Release characteristics ", Chemistry Today, 26, 30-32 (2008) (SCI; JCR 2015 IF = 0.538), cited:15
• H. Hosseinkhani*, M. Hosseinkhani, "Suppression effect of basic fibroblast growth factor on mesenchymal stem cell proliferation activity; Part II: Biological characteristics ", Chemistry Today, 26, 35-37 (2008) (SCI; JCR 2015 IF = 0.538), cited:19
• M. Hosseinkhani, H. Hosseinkhani*, A. Khademhosseini, F. Bolland, H. Kobayashi, S. Prat, "Bone morphogenetic protein-4 enhances cardiomyocytes differentiation of cynomolgus monkey ES cells in Knockout Serum Replacement medium", Stem Cells, 25, 571-580 (2007) (SCI; JCR 2021 IF = 6.277), cited:40
• T. Furong, H. Hosseinkhani, G. Estrada, H. Kobayashi, "Quantitative method for the analysis of cell attachment using the aligned scaffold structure", Journal of Physics, 61, 587-590 (2007) (SCI; JCR 2020 IF = 2.132). cited:6
• M. Hosseinkhani, H. Hosseinkhani*, A. Khademhosseini, " Post-translational modification of GATA-4 involved in the differentiation of monkey ES cell into cardiac myocytesBone morphogenetic protein-4 enhances cardiomyocytes differentiation of cynomolgus monkey ES cells in Knockout Serum Replacement medium", Circulation, 116(16), 202-203 (2007) (SCI; JCR 2021 IF = 29.69), cited:4
• H. Hosseinkhani, M. Yamamoto, Y. Inatsugu, Y. Hiraoka, S. Inoue, H. Shimokawa, Y. Tabata, "Enhanced ectopic bone formation using combination of impregnation of plasmid DNA into 3-D scaffold and bioreactor perfusion culture", Biomaterials, 27, 1387-1398 (2006) (SCI; JCR 2021 IF = 15.304), cited:126
• H. Hosseinkhani*, M. Hosseinkhani, F. Tian, H. Kobayashi, Y. Tabata, "Osteogenic differentiation of mesenchymal stem cells in self-assembled-peptide amphiphile nanofibers ", Biomaterials, 27, 4079-4086 (2006) (SCI; JCR 2021 IF = 15.304), cited:247
• H. Hosseinkhani, T. Azzam, H. Kobayashi, Y. Hiraoka, H. Shimokawa, A.J. Domb, Y. Tabata, "Combination of 3-D tissue engineered scaffold and non-viral gene carrier enhance in vitro DNA expression of mesenchymal stem cells", Biomaterials, 27, 4269-4278 (2006) (SCI; JCR 2021 IF = 15.304), cited:120
• H. Hosseinkhani*, M. Hosseinkhani, F. Tian, H. Kobayashi, Y. Tabata, "Ectopic bone formation in collagen sponge-self assembled peptide amphiphile nanofibers hybrid scaffold in a perfusion culture bioreactor", Biomaterials, 27, 5089-5098 (2006) (SCI; JCR 2021 IF = 15.304), cited:126
• H. Hosseinkhani*, M. Hosseinkhani, A. Khademhosseini, H. Kobayashi, Y. Tabata, "Enhanced angiogenesis through controlled release of basic fibroblast growth factor from peptide amphiphile for tissue regeneration", Biomaterials, 27, 5836-5844 (2006) (SCI; JCR 2021 IF = 15.304), cited:207
• H. Hosseinkhani*, M. Hosseinkhani, H. Kobayashi, "Proliferation and differentiation of mesenchymal stem cells by using self-assembly of peptide-amphiphile nanofibers ", Biomedical Materials, 1, 8-15 (2006) (SCI; JCR 2020 IF = 3.715), cited:93
• H. Hosseinkhani*, M. Hosseinkhani, H. Kobayashi, "Design of tissue-engineered nanoscaffold through self-assembly of peptide amphiphile", Journal of bioactive and compatible polymers, 21, 277-296 (2006) (SCI; JCR 2020 IF = 1.756), cited:112
• H. Hosseinkhani*, Y. Tabata, "Self-assembly of DNA nanoparticles with polycations for the delivery of genetic materials into cells", Journal of Nanoscience and Nanotechnology, 6, 2320-2328 (2006) (SCI; JCR 2021 IF = 1.02), cited:63
• H. Hosseinkhani*, "DNA nanoparticles for gene delivery to cells and tissue", International Journal of Nanotechnology, 3, 416-461 (2006) (SCI; JCR 2014 IF = 1.144), cited:52
• H. Hosseinkhani*, M. Hosseinkhani, A. Khademhosseini, "Emerging Applications of Hydrogels and Microscale Technologies in Drug Discovery", Drug Discovery, 1, 32-34 (2006), cited:21
• H. Hosseinkhani*, M. Hosseinkhani, A. Khademhosseini, "Tissue regeneration through self-assembled peptide amphiphile nanofibers", Cell Journal (Yakhteh), 8, 204-209 (2006) cited:26
• H. Hosseinkhani*, H. Kobayashi, Y. Tabata, "Design of tissue-engineered nano-scaffold using peptide-amphiphile for regenerative medicine", Peptide Science, 2005, 341-344 (2006). (SCI; JCR 2020 IF = 1.905). cited:14
• H. Hosseinkhani*, H. Kobayashi, Y. Tabata, "Selective differentiation cardiomyocyte cells by using peptide-amphiphile nanofibers", Peptide Science, 2005, 63-66 (2006). (SCI; JCR 2020 IF = 1.905). cited:8
• M. Konishi, Y. Tabata, M. Kariya, H. Hosseinkhani, A. Suzuki, K. Fukuhara, M. Mandai, K. Takakura, S. Fujii, "In vivo anti-tumor effect of dual release of cisplatin and adriamycin from biodegradable gelatin hydrogel", Journal of Controlled Release, 103, 7-19 (2005) (SCI; JCR 2021 IF = 11.467), cited:159
• H. Hosseinkhani, Y. Inatsugu, Y. Hiraoka, S. Inoue, H. Shimokawa, Y. Tabata, "Impregnation of plasmid DNA into 3-D scaffold and medium perfusion enhance in vitro DNA expression of mesenchymal stem cells", Tissue Engineering, 11, 1459-1475 (2005) (SCI; JCR 2020 IF = 3.616), cited:74
• H. Hosseinkhani, Y. Inatsugu, Y. Hiraoka, S. Inoue, Y. Tabata, "Perfusion culture enhances osteogenic differentiation of rat mesenchymal stem cells in collagen sponge reinforced with poly (glycolic acid) fiber", Tissue Engineering, 11, 1476-1488 (2005) (SCI; JCR 2020 IF = 3.616), cited:103
• H. Hosseinkhani, T. Azzam, Y. Tabata, A.J. Domb, "Dextran-spermine polycation: an efficient non-viral vector for in vitro and in vivo gene transfection", Gene Therapy, 11, 194-203 (2004), (SCI; JCR 2021 IF = 5.25), cited:172.
• H. Hosseinkhani, T. Aoyama, O. Ogawa, Y. Tabata, "Ultrasound enhances the transfection of plasmid DNA by non-viral vector", Current Pharmaceutical Biotechnology, 4, 109-122 (2003), (SCI; JCR 2021 IF = 2.837), cited:59
• H. Hosseinkhani, T. Aoyama, O. Ogawa, Y. Tabata, "Liver targeting of plasmid DNA by pullulan conjugation based on metal coordination", Journal of Controlled Release, 83, 287-302 (2002) (SCI; JCR 2021 IF = 11.467), cited:103

• H. Hosseinkhani*, "Biomedical Engineering: Materials, Technology, and Applications", Wiley-VCH, ISBN: 9783527347469 (2022). cited: 27
• H. Hosseinkhani*, "Nanomaterials in Advanced Medicine", Wiley-VCH, ISBN: 9783527345496 (2019). cited: 35
• H. Hosseinkhani*, K.L. Ou, "The Nanoscience in Translational Medicine", Wu-Nan Book Inc., ISBN: 978-957-11-7839-4 (2018).
• H. Hosseinkhani*, K.L. Ou "Advanced Biomaterials for Biomedical Engineering", Wu-Nan Book Inc., ISBN: 978-957-11-7169-2 (2018).
• A. Jain, A.J. Domb, H. Hosseinkhani, W. Khan, "Cationic Polymers for the Delivery of Therapeutic Nucleotides", page 1969-1990, In: In: Ramawat, K., Mérillon, JM. (eds) “Polysaccharides, Bioactivity and Biotechnology”, Springer Publication, (2015).
• H. Hosseinkhani*, "Innovation Technology to Engineer 3D Living Organs as Intelligent Diagnostic Tools", In “Characterization and Development of Biosystems and Biomaterials”, Springer Publication, (2013).
• H. Hosseinkhani*, "Controlled release systems for bone regeneration", In “Polymeric Biomaterials, Third Edition, Volume II: Medicinal and Pharmaceutical Applications of Polymers and Technology”, CRC Press/Taylor and Francis, USA (2013).
• H. Hosseinkhani*, M. Hosseinkhani, K. Subramani, "Bone Regeneration using self-assembled nanoparticles-based scaffolds", In “Emerging Nanotechnologies in Dentistry”, Elsevier, UK (2012).
• H. Hosseinkhani*, M. Hosseinkhani, "Tissue Engineered Scaffolds for Stem Cells and Regenerative Medicine", In “Trend in Stem Cells Biology and Technology”, HUMANANA Press Inc., USA (2009).
• H. Hosseinkhani*, M. Hosseinkhani, S. Zhang, K. Subramani "Self-assembly of nanomaterials for engineering cell microenvironment", In “Micro and Nanoenginernig of the cell microenvironment: Applications and Technologies” Artech House Publishers, USA (2008).
• H. Hosseinkhani*, M. Hosseinkhani, A. Khademhosseini, "Emerging Technology of Hydrogels in Drug Discovery", In “Topics in Multifunctional Biomaterials and Devices” London, UK (2007).
• H. Hosseinkhani, T. Aoyama, O. Ogawa, Y. Tabata, "Tumor targeting of plasmid DNA by dextran conjugation based on metal coordination", In Key Engineering Materials, Vols. 288-289, pp 109-112, Trans Tech Publications, Switzerland (2005).
• M. Yamamoto, H. Hosseinkhani, "Liver targeting of plasmid DNA by polymer-metal conjugation" pp 119-132, Yodosha Tech Publications, Japanese version, Med Tech Publications, JAPAN (2004).

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