Dr. Yusuf Oloruntoyin Ayipo is an Assistant Professor at the Department of Chemistry and Industrial Chemistry, Kwara State University, Malete, Ilorin, Nigeria, with over nine years of experience in teaching and research at university levels. He has a PhD in Medicinal Chemistry, and an MSc and BSc in Chemistry with relevant skills. His expertise covers relevant disciplines including Drug Design, Bioorganic and Bioinorganic Chemistry, Biochemistry, Pharmacology and Pharmaceutical Sciences. His research interests include computer-aided drug design, synthesis and biological studies of bioactive molecules for neurological disorders, cancers and microbial diseases. He has made significant contributions to basic, pre-clinical and advanced studies on the mechanisms of human diseases and therapeutic designs with over fifty impact peer-reviewed publications. He has received prestigious awards including a PhD Scholarship by TETFUND Nigeria (2019), Graduate Assistant Fellowship, Universiti Sains Malaysia (2019-2022), Best Poster Presenter, CDR Colloquium, Universiti Sains Malaysia (2019), Sci-Mix Presenter, ACS SciMeeting, Atlanta (Fall 2021) and Sanggar Sanjung Award of Excellence in Publication, Universiti Sains Malaysia, 2021 and 2022. In addition, he has held several leadership positions, playing critical professional roles such as Editorial Board Member of reputable journals: BMC Molecular and Cell Biology, Discover Chemistry and Plos One, Guest Editor for Frontiers in Antibiotics and a Peer-Reviewer for over 20 journals. He is open to collaboration on exploration for solutions to human diseases through effective prevention and treatment.

• Molecular Modelling
• Molecular Docking
• Molecular Dynamics
• Pharmacology
• ADMET Studies
• Neuropharmacological Agents
• Anticancer
• Antimicrobials
• Therapeutic Targets
• Drug Design
• Disease Mechanisms
• Bioorganic Chemistry
• Natural Product Chemistry
• Biological Studies
• Antidiabetic Agents

• Ayipo Y. O., Chong C. F., Najib Y. S., Mordi M. N., (2024) Molecular interactions and toxicological evaluation of some synthesized piperazine-linked carbazole derivatives in vivo zebrafish (Danio rerio). (Draft)
• Ayipo Y. O., Chong C. F., Najib Y. S., Mordi M. N. (2024) Molecular modelling, synthesis and antidepressant behavioural study of some carbazole derivatives in adult zebrafish model. (Draft)
• Ayipo Y. O., Chong C. F., Abdulamed H. T., Mordi M. N.: Bioactive alkaloidal and phenolic phytochemicals as promising epidrugs for diabetes mellitus 2: A review of recent development. Fitoterapia, 175 (2024), 105922. https://doi.org/10.1016/j.fitote.2024.105922 [Q3, JCR IF: 2.5, Cite Score: 5..3 (2023)]; [Q2, SJR 0.57 (2023)]
• Ajiboye A. T., Asekun O. T., Ayipo Y. O., Mordi M. N., Familoni O. B., Ali Z., Khan I. A.: Phytochemicals and enzymes inhibitory potentials of leaves and rootbarks of Sarcocephallus latifolius (smith): In vitro and in silico investigations. Fitoterapia, 176 (2024) 106037. https://doi.org/10.1016/j.fitote.2024.106037 [Q3, JCR IF: 2.5, Cite Score: 5.3 (2023)]; [Q2, SJR 0.57 (2023)]
• Ayipo Y. O., Ahmad I., Chong C. F., Zainurin N. A., Najib S. Y., Patel H., Mordi M. N.: Carbazole derivatives as promising competitive and allosteric inhibitors of human serotonin transporter: computational pharmacology, Journal of Biomolecular Structure and Dynamics, 2024, 42(2), 1-22. https://doi.org/10.1080/07391102.2023.2198016 [Q2, JCR IF: 2.7, Cite Score: 8.9 (2023)]; [Q2, SJR 0.5 (2023)]
• Ibrahim S. O., Lukman H. Y., Abdulkadir F. R., Bello M. Y., Ayipo Y. O., Babamale H. F., Zubair M. F., Atolani O.: Nanoparticles as Antioxidant Agents: A Comprehensive Review, Al-Bahir Journal of Engineering and Pure Sciences, 2024, 5:17-35. https://doi.org/10.55810/2313-0083.1066 [Non-Indexed]
• Ayipo Y. O., Chong C. F., Mordi M. N.: Small-molecule inhibitors of bacterial-producing metallo-β-lactamases: insights into their resistance mechanisms and biochemical analyses of their activities, RSC Medicinal Chemistry, 2023, 14, 1012-1048. https://doi.org/10.1039/D3MD00036B [Q2, JCR IF: 4.1, Cite Score: 5.8 (2023)]; [Q1, SJR 0.85 (2023)]
• Najib Y. S., Ayipo Y. O., Alananzeh W. A., Muhammed M., Mordi M. N., The Discovery of Putative Small Molecules via Ligand-based Pharmacophore Modelling Targeting Human Tau Protein for an Effective Treatment of Parkinson’s Disease, Malaysian Journal of Medicine and Health Sciences, 2023, 19(6), 83-94. https://doi.org/10.47836/mjmhs.19.6.12 [Q4, SJR 0.14 (2023)]
• Alananzeh W. A., Al-qattan M. N., Ayipo Y. O., Mordi M. N. N‑substituted tetrahydro‑beta‑carboline as mu‑opioid receptors ligands: in silico study; molecular docking, ADMET and molecular dynamics approach design, Molecular Diversity, 2023, 1-17 https://doi.org/10.1007/s11030-023-10655-1 [Q2, JCR IF: 3.9 (2023)]; [Q2, SJR 0.59 (2023)]
• Lawal B. A., Ayipo Y. O., Adekunle A. O., Amali M. O., Badeggi U. M., Alananzeh W. A., Mordi M. N.: Phytoconstituents of Datura metel extract improved motor coordination in haloperidol-induced cataleptic mice: Dual-target molecular docking and behavioural studies, Ethnopharmacology, 2023, 300(1), 115753. https://doi.org/10.1016/j.jep.2022.115753 [Q2, JCR IF: 4.8, Cite Score 10.3 (2023)]; [Q1, SJR 0.94 (2023)]
• Najib Y. S., Ayipo Y. O., Alananzeh W. A., Ajmal A., Shams S., Wadood A., Mordi M. N., Potent Small Molecules Inhibitors Discovery through Ligand-based Modelling for Effective Treatment of Parkinson’s Disease, Letters in Drug Design & Discovery, 2023, XX, 1-17. https://doi.org/10.2174/1570180820666230822094954 [Q4, JCR IF: 1.2, (2023)]; [Q3, SJR 0.22 (2023)]
• Ayipo Y. O., Ahmad I., Najib Y. S., Sheu S. K., Patel H., Mordi M. N., Molecular modelling and structure-activity relationship of a natural derivative of ohydroxybenzoate as a potent inhibitor of dual NSP3 and NSP12 of SARS-CoV-2: in silico study, Journal of Biomolecular Structure and Dynamics¸2023, 41(5), 1-19. https://doi.org/10.1080/07391102.2022.2026818 [Q2, JCR IF: 2..7, Cite Score: 8.9 (2023)]; [Q2, SJR 0.5 (2023)]
• Yao T. X., Ayipo Y. O. Mordi M. N. In silico pharmacological evaluation of tetrahydro-β-carboline derivatives as putative inhibitors of alpha-synuclein and dopa decarboxylase for Parkinson’s disease, Trends in Science, 2023, 20(11): 6008. https://doi.org/10.48048/tis.2023.6008 [Q3, SJR 0.19 (2023)]
• Ayipo Y. O., Ahmad I., Alananzeh W. A., Lawal A., Patel H., Mordi M. N.: Computational modelling of potential Zn-sensitive non-β-lactam inhibitors of imipenemase-1 (IMP-1), Journal of Biomolecular Structure and Dynamics, 2022, 41(19), 1-22. https://doi.org/10.1080/07391102.2022.2153168 [Q2, JCR IF: 2.7, Cite Score: 8.9 (2023)]; [Q2, SJR 0.5 (2023)]
• Ayipo Y. O., Ajiboye A. T., Osunniran W. A., Jimoh A. A., Mordi M. N.: Epigenetic oncogenesis, biomarkers and emerging chemotherapeutics for breast cancer, BBA-Gene Regulatory Mechanisms, 2022, 1865(7), 194873. https://doi.org/10.1016/j.bbagrm.2022.194873 [Q1, JCR IF: 2.6, Cite Score: 9.2 (2023)]; [Q1, SJR 1.38 (2023)]
• Ayipo Y. O., Alananzeh W. A., Ahmad I., Patel H., Mordi M. N.: Structural modelling and in silico pharmacology of β-carboline alkaloids as potent 5-HT1A receptor antagonists and reuptake inhibitors. Journal of Biomolecular Structure and Dynamics, 2022, 41(13), 1-18. https://doi.org/10.1080/07391102.2022.2104376 [Q2, JCR IF: 2.7, Cite Score: 8.9 (2023)]; [Q2, SJR 0.5 (2023)]
• Najib S. Y., Ayipo Y. O., Alananzeh W. A., Mordi M. N.: Ligand-Based Pharmacophore Modelling Targeting α-Synuclein Misfolding for an Effective Treatment of Parkinson’s Disease, Applications of modelling and simulation, 2022, 6, 122-133. [Non-Indexed]
• Osunniran W. A., Ayipo Y. O., Abdullahi R. O., Adebayo T. B., Bamigboye M. O., Obaleye J. A.: Heteroleptic transition metal complexes of eflornithine hydrochloride monohydrate: synthesis, characterization, in silico and in vitro biological studies, Journal of the Turkish Chemical Society, 2022, 9(4), 1309-1322. https://doi.org/10.18596/jotcsa.1142442 [Q3, SJR 0.21 (2023)]
• Ayipo Y. O., Alananzeh W. A., Yahaya S. N., Mordi M. N., Molecular modelling and virtual screening to identify new piperazine conjugates as potent human 5-HT1A antagonists and reuptake inhibitors, Combinatorial Chemistry and High Throughput Screening, 2022, May, Online Ahead of Print. https://doi.org/10.2174/1386207325666220524094913 [Q3, JCR IF: 1.3, (2023)]; [Q3, SJR 0.3 (2023)]
• Ahmad I., Pawara R. H., Girase R. T., Pathan A. Y., Jagatap V. R., Desai N., Ayipo Y. O., Surana S. J., Patel H., Synthesis, Molecular Modeling, and Quantum-Chemical-Based Investigations of Isoindole-1,3-diones as Antimycobacterial Agents, ACS Omega, 2022, 7(25), 21820-21844. https://doi.org/10.1021/acsomega.2c01981 [Q2, JCR IF: 3.7, Cite Score 6.6 (2023)]; [Q2, SJR 0.71 (2023)]
• Jimoh A. A., Akpeji B. H., Azeez S. O., Ayipo Y. O., Abdulsalam Z. A., Adebayo Z. F., Ajao A. T., Zakariyah A. T., Elemike E. E., Biosynthesis of Ag and TiO2 nanoparticles and the evaluation of their antibacterial activities, Inorganic Chemistry Communications, 2022, 14(7), 109503. https://doi.org/10.1016/j.inoche.2022.109503 [Q1, JCR IF: 4.4, Cite Score 5.5 (2023)]; [Q1, SJR 0.64 (2023)]
• Ayipo Y. O., Osunniran W. A., Babamale H. F., Ayinde M. O. Mordi M. N., Metalloenzyme mimicry and modulation strategies to conquer antimicrobial resistance: Metal-ligand coordination perspectives, Coordination Chemistry Reviews, 2022, 453(2) 214317 https://doi.org/10.1016/j.ccr.2021.214317 [Q1, JCR IF: 20.3, Cite Score 34.3 (2023)]; [Q1, SJR 4.15 (2023)]
• Ayipo Y. O. Alananzeh W. A., Abdulsalam Z. A., Badeggi U. M., Jimoh A. A., Osunniran W. A., Mordi M. N. Structure-based design and molecular simulations identified some quercetin-based drugs as repurposable inhibitors of SARS-CoV-2 main protease, Trends in Science, 2022, 19(21), 2257. https://doi.org/10.48048/tis.2022.2557 [Q3, SJR 0.19 (2023)]
• Najib S. Y., Ayipo Y. O., Damodaran T., Mordi M. N., Potential Alternative Inhibitors of Alpha-Synuclein and Effective Treatment of Parkinson’s Disease, Tropical Journal of Natural Product Research, 2022, 6(5), 694-704. https://www.doi.org/10.26538/tjnpr/v6i5.6 [Q3, SJR 0.18 (2023)]
• Ayipo Y. O., Bakare A. A., Badeggi U. M., Jimoh A. A., Lawal A., Mordi M. N., Recent developments on gold and silver nano biomaterials for human viral diseases, Current Research in Chemical Biology, 2022, 2, 100021. https://doi.org/10.1016/j.crchbi.2022.100021 [Non-Indexed]
• Yahaya S. N., Ayipo Y. O. Mordi M. N. Utilization of Physical and Chemical Microbial Load Reduction Agents for SARS-CoV-2: Implications on Toxicity and Development of Drug Resistance, Journal of Applied Pharmaceutical Science, 2022, 12(01), 001-028. https://doi.org/10.7324/JAPS.2021.120101 [Q2, SJR 0.26 (2023)]
• Ayipo Y. O., Yahaya S. N., Babamale H. F., Ahmad I., Patel H., Mordi M. N., β-carboline alkaloids induce structural plasticity and inhibition of SARS-CoV-2 nsp3 macrodomain more potently than remdesivir metabolite GS-441524: Computational approach, Turkish Journal of Biology, 2021, 45(SI-1) 503-517. https://doi.org/10.3906/biy-2106-64 [Q3, JCR IF: 1.1, (2023)]; [Q2, SJR 0.38 (2023)]
• Ayipo Y. O., Yahaya S. N., Alananzeh W. A., Babamale H. F., Mordi M. N., Pathomechanisms, therapeutic targets and potent inhibitors of some beta-coronaviruses from bench, Infection, Genetics and Evolution, 2021, 93(09) 104944. https://doi.org/10.1016/j.meegid.2021.104944 [Q3, JCR IF: 2.6, Cite Score 8.4 (2023)]; [Q1, SJR 0.72 (2023)]
• Ayipo Y. O., Osunniran W. A., Badeggi U. M., Saheed I. O., Jimoh A. A., Olaide E. O., Obaleye J. A., Synthesis, characterization and biological study of Co(II) and Cu(II) complexes of mixed ligands of piperaquine and diclofenac, Journal of the Turkish Chemical Society: Chemistry A, 2021, 8(2) 633-650. https://doi.org/10.18596/jotcsa.898523 [Q3, SJR 0.21 (2023)]
• Ayipo Y. O, Osunniran W. A., Mordi M. N., Metal complexes of β-carboline: Advances in anticancer therapeutics, Coordination Chemistry Reviews, 2021, 432C, 213746 https://doi.org/10.1016/j.ccr.2020.213746 [Q1, JCR IF: 20.3, Cite Score 34.3 (2023)]; [Q1, SJR 4.15 (2023)]
• Ayipo Y. O., Mordi M. N., Muzaimi M., Damodaran T., Neuropharmacological potentials of β-carboline for neuropsychiatric disorder, European Journal of Pharmacology, 2021, 893, 173837 https://doi.org/10.1016/j.ejphar.2020.173837 [Q1, JCR IF: 4.4, Cite Score 9.0 (2023)]; [Q1, SJR 1.06 (2023)]
• Ayipo Y. O., Alananzeh W. A., Yahaya S. N., Mordi M. N., Identification of multi-target directed inhibitors of SARS-CoV-2: Drug repurposing, Research Square (Preprint), 2021, 1-31. https://doi.org/10.21203/rs.3.rs-335733/v1 [Non-Indexed]
• NaAllah A., Ayipo Y. O., Komolafe D. I., Solihu S., Bamidele B., Alabi M. A., Balogun A., Abdulazeez A. T., Mordi M. N., Phytochemical screening and in silico pharmacological profiling of ethanolic extract of Aframomum melegueta for prostate carcinoma, Journal of Applied Pharmaceutical Science, 2021, 10(07): 132-145. https://doi.org/10.7324/JAPS.2021.110715 [Q2, SJR 0.26 (2023)]
• Osunniran W. A., Obaleye J. A., Tella A. C., Ayipo Y. O., Bale A. T., Rajee A. O., Toxicological assessment of synthesized and characterized transition metal (ii) complexes of eflornithine hydrochloride hydrate on albino rats, Bulletin of the Chemical Society of Ethiopia, 2021, 34 (3), 489-500 https://doi.org/10.4314/bcse.v34i3.6 [Q3, JCR IF: 1.3 (2023)]; [Q3, SJR 0.23 (2023)]
• Badeggi U. M., Lawal B. A., Akinfenwa A. O., Ayipo Y. O., Azeh Y., Dagaci M. Z., Physicochemical properties and in vitro stability studies of green synthesized gold nanoparticles using pelargonium sidoides. Nigerian Journal of Technology, 2020; 39(3): 785-791. https://doi.org/10.4314/njt.v39i3.18 [Non-Indexed]
• Badeggi, U.M., Muhammad, K.T., Lawal, B.A., Ayipo, Y.O., Okonkwo, T.P., Azeh, Y. Biosynthesis, characterization and antidiabetic activity of gold nanoparticles using the stem bark extract of leucosidea sericea (old wood), Lapai Journal of Science and Technology, 2020, 6(1) 20-31. [Non-Indexed]
• Osunniran W. A., Ayipo Y. O, Adeyemo M. A., Bale A. T., Obaleye J. A., Comparison of Solid and Solvent - Based Syntheses, Characterization and Antioxidant Property of Metal Complexes of Sodium Diclofenac, Fountain Journal of Natural and Applied Science, 2020; 9: 1. https://www.fountainjournals.com/index.php/FUJNAS/article/view/291 [Non-Indexed]
• Osunniran, W.A., Obaleye, J.A., Tella, A.C., Bamigboye, M.O., Ayipo Y. O., Rajee, A.O., Amolegbe S.A (2020) Synthesis, Spectral and Chemotherapeutic Potentials of some Metal(II) Difluoromethylorthine Complexes, Centrepoint Journal (Science Edition), 2020, 26(2): 78-102. [Non-Indexed]
• Ayipo Y. O., Osunniran W. A., Badeggi U. M., Ayinde O. M., Octahedral Platinum (IV) Complexes of Mixed Piperaquine, Sulfadoxine and Pyrimethamine: Synthesis, Spectroscopy, Antioxidant and Antibacterial Studies, Research Journal of Chemical Sciences., Volume 9, Issue (3), Pages 24-39, July,18 (2019). http://www.isca.in/rjcs/Archives/v9/i3/4.ISCA-RJCS-2019-012.php [Non-Indexed]
• Osunniran W. A., Ayipo Y. O., Obaleye J. A., Six Coordinate Transition Metal(II) Complexes of Eflornithine Hydrochloride Hydrate and 2,2-Bipyridine as Secondary Ligand: Synthesis, Characterization and Antibacterial Study. Jordan Journal of Chemistry, 2018, 13(3), 149-157. https://jjc.yu.edu.jo/Issues/Vol13No3PDF/2.pdf [Q4, JCR IF: 0.4 (2023)]; [Q4, SJR 0.12 (2023)]
• Saheed I. O., Azeez S. O., Ayipo Y. O., Gunu U. C., Assessment of Physicochemical Characteristics of Selected Borehole Waters in Oke-Oyi Community, Ilorin East Local Government Area, Kwara State. Journal of Applied Science and Environmental Management October 2017, Vol. 21 (6) 1127-1129 https://doi.org/10.4314/jasem.v21i6.22 [Non-Indexed]
• Ayipo Y. O., Obaleye J. A., Badeggi U. M., Novel metal complexes of mixed piperaquine-acetaminophen and piperaquine-acetylsalicylic acid: synthesis, characterization and biological activities. Journal of the Turkish Chemical Society A. 2017; 4(1): 313-326 http://doi.org/10.18596/jotcsa.287331 [Q3, SJR 0.21 (2023)]
• Ayipo Y. O., Najib Y. S., Alananzeh W. A., Adebayo Z. F., Mordi M. N., Screening of repurposable natural products database to identify potent small-molecule inhibitors of SARS-CoV-2 spike glycoprotein, Technoscience Journal for Community Development in Africa 2024. (In Press).

• Ayipo Y. O., Otun K. B., Jimoh A. A., Mordi M. N. (2025) New and emerging applications of hydrogen including industrial, medical and warfare applications, Accelerating the transition to Hydrogen Economy Vol 1 Production, ISBN: 9780443223990, Edited by Kurniawan and Prasad, To be Published by Elsevier Inc., Page 211-234. https://doi.org/10.1016/B978-0-443-14039-6.00012-9
• Ayipo Y. O., Chong C. F., Jimoh A. A., Abdulra’uf L. B., Osunniran W. A. (2024) The fate of pesticides in wastewater: A review, Pesticides in Wastewater: Removal Methods and Future Trends, Edited by Pranav Pathak, To be Published by Apple Academic Press, USA (In Press)
• Ayipo Y. O., Badeggi U. M., Ajiboye T. A., Mordi M. N., (2024) Extraction of Phenolic Compounds from some Ayurvedic Botanicals (Nigella sativa, Andrographis paniculata and Phyllanthus amarus) and Evaluation of their Antibacterial and Antiviral Properties using Bioinformatics Approaches, Chapter 4 in Computational Approaches in Biomaterials, Bioinformatics and Biomedical Engineering Applications, Edited by Pranav Pathak, Published by CRC Press, Taylor & Francis Group, Florida, USA. https://doi.org/10.1201/9781003354437-4
• Dauda K. A,. Olorede K. O., Banjoko A. W., Yahya W. B.. Ayipo Y. O., (2024) Genetic Diagnosis, Classification, and Risk Prediction in Cancer Using Next-Generation Sequencing in Oncology, Chapter 5 in Computational Approaches in Biomaterials, Bioinformatics and Biomedical Engineering Applications, Edited by Pranav Pathak, Published by CRC Press, Taylor & Francis Group, Florida, USA. https://doi.org/10.1201/9781032699882-5
• Azeez S. A., Saheed I. O., Jimoh A. A., Ayipo Y. O., (2024) Treatment of Pharmaceutical Wastewater by Adsorption Using Functionalized Carbon-Based Adsorbents, Recent Approaches for Water and Wastewater Treatment, Edited by Pranav Pathak, To be Published by Apple Academic Press/CRC Taylor & Francis Group, Florida, USA. https://www.appleacademicpress.com/advances-in-water-and-wastewater-treatment-theoretical-and-experimental-approaches/9781774917039)
• Ayipo Y. O., Badeggi U. M., Jimoh A. A., Mordi M. N., (2023) Silver nanoparticles for treatment of COVID-19 and other viral diseases, Chapter 17, pp 313-336, in Silver nanoparticles for drug delivery, Edited by Prashant Kesharwani, Published by Elsevier Inc. https://doi.org/10.1016/B978-0-443-15343-3.00013-9
• Ayipo Y. O., Chong C. F., Mordi M. N. (2023) Recent Advances in Small-molecule Broad-spectrum Inhibitors of Bacterial Metallo-β-lactamases, Pharma Focus Asia e-Book, Issue 53, 15-19. https://www.pharmafocusasia.com/e-book

• https://orcid.org/0000-0001-5951-9788
• https://www.scopus.com/authid/detail.uri?authorId=57221614418
• https://www.webofscience.com/wos/author/record/AAG-3480-2021