Editor Profile
Dr. Francesca Costabile, Ph.D.
Postdoctoral Researcher
May 2022 - Present
University of Pennsylvania
Philadelphia
United States
Dr. Francesca Costabile is a Postdoctoral Researcher in the Radiation Oncology Department at the University of Pennsylvania School of Medicine. With a robust academic background, she holds a Master's degree in Biology and a Ph.D. in Clinical and Experimental Immunology. Her work in oncology research is dedicated to improving therapeutic strategies and advancing the understanding of cancer biology.
Originally from Torre del Greco, a coastal town in Italy, Francesca now resides in Philadelphia, where she contributes to cutting-edge research while also enjoying the city's vibrant culture. Her professional journey is guided by a strong commitment to scientific excellence and a deep desire to contribute to the betterment of humanity. One of their primary professional goals is to eventually become a journal editor, shaping the future of scientific publishing.
Francesca embodies the mission of "respect and professionalism" in all of her endeavors, always striving to maintain a high standard of integrity in their work and collaborations. She prides herself on being a fast learner and a dedicated worker, constantly challenging herself to grow both personally and professionally. Her critical thinking and exceptional writing skills are key strengths that contribute to the success of her research projects.
Outside of her professional life, Francesca has a passion for music, cooking, and exploring nature. These hobbies provide balance and inspire creativity, both in and outside the lab. However, Francesca remains focused on using their scientific expertise to make a meaningful impact on society.
- Immunology
- Cell Biology and Signaling
- Reducing the Use of Mice in Experimentation by Advancing 3D Model Systems
- Vaccines
- Cancer
- TCR Biology
- S1P kinases axis promotes IL-17 expression in human T lymphocytes. Scientific Reports. 2018.
- Targeting mitochondria in cancer: current concepts and immunotherapy approaches. Transl Res. 2018.
- Combination of vasculature targeting, hypofractionated radiotherapy and immune checkpoint inhibitor elicits potent antitumor immune response and blocks tumor progression. J Immunother Cancer. 2021.
- Development of Exhaustion and Acquisition of Regulatory Function by Infiltrating CD8+CD28- T Lymphocytes Dictate Clinical Outcome in Head and Neck Cancer. Cancers (Basel). 2021.
- Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy. Mol Ther. 2022.
- Parkin deficiency suppresses antigen presentation to promote tumor immune evasion and immunotherapy resistance. Cancer Res. 2023.
- Local radiation enhances systemic CAR T-cell efficacy by augmenting antigen crosspresentation and T-cell infiltration. Blood Avd. 2024.
- NECTIN-4-redirected T Cell Antigen Coupler (TAC) T Cells Bearing CD28 Show Superior Antitumor Responses Against Solid Tumors. Front Immunol. 2024.
