I am a CNPq (National Council for Research and Development) research productivity fellow and a Scientist of Our State (CNE) from FAPERJ. From 2014 to 2016, I was deputy secretary of the Rio Regional Office of the Brazilian Chemical Society (SBQ-Rio). In 2007, I was the Undersecretary of Health for the city of Niterói, RJ. I have a degree from the School of Pharmacy of the Federal University of Rio de Janeiro (UFRJ), a master's degree in organic synthesis from the Center for Natural Products Research (NPPN) at UFRJ, a PhD in chemistry from the Institute of Chemistry (IQ) at UFRJ, and a "sandwich" internship at the University of York, England. I did a postdoctoral internship at the London School of Hygiene and Tropical Medicine in London, England. I am a master's and doctoral advisor for the permanent staff of the Postgraduate courses in Translational Research of Drugs and Medications at Fiocruz, in the Pharmacology and Medicinal Chemistry Program of the Institute of Biomedical Sciences - ICB-UFRJ. I have trained 37 master's and 18 doctoral students. I am a senior technologist at the Oswaldo Cruz Foundation (FIOCRUZ), and since 1986 I have held several positions, including Executive Director of Farmanguinhos. I am currently Vice-Director of Education, Research and Innovation at Farmanguinhos, coordinating several Fiocruz projects. I lead one of the most important RDI groups in drug synthesis in the state of Rio de Janeiro, aiming at the public production of drugs and medications. Numerous syntheses of important drugs for public health have been developed under my coordination, and the technologies have been transferred to the national pharmaceutical chemical industry. In the field of innovation, my main focus is RDI in pharmaceuticals, with experience in the area of ​​organofluorine and heterocycle chemistry, with an emphasis on Medicinal Pharmaceutical Chemistry. Several hundred novel molecules for neglected diseases, AIDS and cancer have been synthesized, generating potent antimalarials, antimycobacterials, antichagasics, antiretrovirals and antileukemics, which are described in 150 publications, with a high impact index, and 48 patents. I am a reviewer for several important international journals, such as: J. Medicinal Chemistry, European J. Med. Chemistry, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Bioorganic Medicinal Chemistry, ACS Omega and others. During my years as a scientist at Fiocruz, I have dedicated myself to the cause of improving access to medicines for users of the Unified Health System (SUS), with numerous successful contributions. I have accumulated several awards such as the Walter Morse Medal from SBQ-Rio, the Fiocruz Merit Plaque, Merit for technological work at GESTEC-Fiocruz, for Dedication at Farmanguinhos, the RVq-SBQ Medal, among others. In 2021, I won the Women of Fiocruz and the international Brazilian Women in Chemistry award, in the Leadership in Industry category.given by the American Chemical Society in partnership with the Brazilian Chemical Society.

• Medicinal Chemistry on Neglected Diseases
• Malaria
• Tuberculosis
• Chagas Diseases
• Leishmaniasis etc.

• OF JESUS ​​HILLER, NOEMI; PIMENTA SALLES, JULIANA; VILLAS BÔAS HOELZ, LUCAS ; COSTA ZORZANELLI, BRUNA; AMORIM FERNANDES, TÁCIO VINICIO; Boechat, Nubia ; BY LUNA MARTINS, DANIELA; XAVIER FARIA, ROBSON . α-Cyanocinnamylboronic acid derivatives are safe, selective anti-inflammatory molecules that inhibit P2X7 receptor function and signaling. BIOMEDICINE & PHARMACOTHERAPY , v. 185, p. 117945, 2025.
• Molluscicidal and Schistosomicidal Activities of 2- (1H-Pyrazol-1-yl) -1,3,4-thiadiazole Derivatives. PHARMACEUTICALS , v. 18, p. 429, 2025.
• FEITOSA, LIVIA M. ; FRANCA, RODOLFO RODRIGO F. ; Ferreira, Maria de Lourdes G. ; AGUIAR, ANNA CC ; DE SOUZA, GUILHERME E. ; MALUF, SARAH EL CHAMY ; DE SOUZA, JULIANA O. ; ZAPATA, LUANA ; DUARTE, DENISE ; MORAIS, INES; NOGUEIRA, FATIMA ; NONATO, M. CRISTINA ; Pinheiro, Luiz CS ; GUIDO, RAFAEL VC ; Boechat, Nubia . Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , v. 267, p. 116163, 2024.
• Spirooxadiazoline -oxindoles derived from imatinib show antimyeloproliferative potential in K562 cells. ARCHIV DER PHARMAZIE , v . 2024, p. 1-10, 2024.
• PITOMBEIRA, MARCELLY CSR ; JUNIOR, POLICARPO AS ; MURTA, SILVANE MARIA FONSECA ; ROMANHA, ALVARO ; LUCCAS, PEDRO H. ; NONATO, M. CRISTINA ; ROCHA, RAFAEL EO ; FERREIRA, RAFAELA S. ; DA SILVEIRA, FLÁVIA F. ; CASTELO'BRANCO, FREDERICO S. ; CARVALHO, ALCIONE S. ; Boechat, Nubia . New 2-nitroimidazole- -acylhydrazones, analogs of benznidazole, as anti- agents. ARCHIV DER PHARMAZIE , v. 2024, p. 1-12, 2024.
• INACIO LEITE, DEBORA ; FERREIRA PIMENTEL, LUIZ CLAUDIO ; CONCEIÇÃO AVELINO DIAS, MARIA DA ; MACEDO BASTOS, MONICA ; Boechat, Nubia . Alternative Reactions to Friedel-crafts Acylation on Highly Activated Substrates. CURRENT ORGANIC CHEMISTRY , v. 28, p. 1-10, 2024.
• RAMOS, LAÍS GOMES ; DE SOUZA, KÁTIA REGINA ; JÚNIOR, POLICARPO ADEMAR SALES ; CÂMARA, CAMILA CAPELINI ; CASTELO-BRANCO, FREDERICO S. ; Boechat, Nubia ; CARVALHO, SAMIR AQUINO . Tackling the Challenges of human Chagas Disease: a Comprehensive Review of Treatment Strategies in the Chronic Phase and Emerging Therapeutic Approaches. ACTA TROPICA , v. 2024, p. 107264, 2024. 
• RAMOS, LAÍS G. ; DE SOUZA, KÁTIA R. ; BARBOSA, JULIANA MC ; SALOMÃO, KELLY ; SALES JUNIOR, Policarpo A. ; PEREIRA, VALÉRIA RA ; MURTA, SILVANE MF ; FERREIRA, RAFAELA S. ; BERNARDES, TALITA CD ; WARDELL, SOLANGE MSV ; Wardell, James L. ; Boechat, Nubia ; CARVALHO, SAMIR A. . Synthesis and activity of benzimidazole N-Acylhydrazones against Trypanosoma cruzi, Leishmania amazonensis and Leishmania infantum. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , v. 110, p. 129876, 2024.
• Ponatinib: A Review of the History of Medicinal Chemistry behind Its Development. PHARMACEUTICALS , v . 17, p. 1361-1388, 2024.
• A Review of the Development of Multitarget Molecules against HIV-TB Coinfection Pathogens. MOLECULES , v . 28, p. 3342, 2023.
• In silico and in vitro assessment of anti-Trypanosoma cruzi efficacy, genotoxicity and pharmacokinetics of pentasubstituted pyrrolic atorvastatin-aminoquinoline hybrid compounds. ACTA TROPICA , v . 2023 , p. 106924-106962, 2023.
• Antiplasmodial, Trypanocidal, and Genotoxicity In Vitro Assessment of New Hybrid α,α-Difluorophenylacetamide-statin Derivatives. PHARMACEUTICALS , v. 15, n . 2 , p . 16, p. 782-804, 2023. 
• In vitro evaluation of 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole derivatives against replicative and infective stages of Trypanosoma cruzi. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES , v. 2023, p. 1-8, 2023.
• MENOZZI, CHEYENE ALMEIDA CELESTINO ; FRANCE, RODOLFO RODRIGO FLORIDO ; LUCCAS, PEDRO HENRIQUE ; BAPTISTA, MAYARA DOS SANTOS ; FERNANDES, TÁCIO VINÍCIO AMORIM ; HOELZ, LUCAS VILLAS BÔAS ; SALES JUNIOR, POLICARPO ADEMAR ; MURTA, SILVANE MARIA FONSECA ; ROMANHA, ALVARO ; GOLDSTEIN, ALANA DA CUNHA ; ARAUJO-LIMA, CARLOS FERNANDO ; FELZENSZWALB, ISRAEL ; NONATO, MARIA CRISTINA ; BOECHAT, Nubia . Anti-Trypanosoma cruzi Activity, Mutagenicity, Hepatocytotoxicity and Nitroreductase Enzyme Evaluation of 3-Nitrotriazole, 2-Nitroimidazole and Triazole Derivatives. MOLECULES , v. 28, p. 7461-7481, 2023.
• MAFRA, JOÃO CARLOS MARTINS ; Boechat, Nubia ; TEIXEIRA, GUILHERME PEGAS ; FARIA, ROBSON XAVIER . Synthetic molecules as P2X7 receptor antagonists: A medicinal chemistry update focusing the therapy of inflammatory diseases. EUROPEAN JOURNAL OF PHARMACOLOGY , v. 957, p. 175999, 2023. 
• LEITE, DEBORA I. ; CAMPANIÇO, ANDRE ; COSTA, PEDRO AG ; CORREA, ISADORA A. ; DA COSTA, LUCIANA J. ; Bastos, Monica M. ; MOREIRA, RUI ; LOPES, FRANCISCA ; JORDAAN, AUDREY ; WARNER, DIGBY F. ; Boechat, Nubia . New azaaurone derivatives as potential multitarget agents in HIV-TB coinfection. ARCHIV DER PHARMAZIE , v. 2023, p. 1-15, 2023
• MARTINS GOUVÊA, MARCOS ; CORRÊA DE CARVALHO, RENATA ; SILVA CASTELO-BRANCO, FREDERICO ; Boechat, Nubia ; DUARTE PEREIRA NETTO, ANNIBAL ; FERREIRA DE CARVALHO MARQUES, FLÁVIA . The cleavage kinetics of hydrazide derivatives of isoniazid by HPLC-UV/DAD and its impact on activity against Mycobacterium tuberculosis. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES , v. 1188, p. 123080, 2022. 
• OLIVEIRA, ANDRESSA ; MOURA, STEFANY ; PIMENTEL, LUIZ ; NETO, JOÃO ; DANTAS, RAFAEL ; SILVA-JR, FLORIANO ; BASTOS, MONICA ; Boechat, Nubia . New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells. MOLECULES , v. 27, p. 750, 2022. 
• Santos, CR ; PIMENTEL, L. ; CANZIAN, HENAYLE FERNANDES ; OLIVEIRA, AP ; S JUNIOR, FP ; DANTAS, RF ; Hoelz, LVB ; LEITE FIRMINO MARINHO, DEBORA INACIO ; CUNHA, AC ; BASTOS, MM ; Boechat, Nubia . Hybrids of ImatinibwithQuinoline: Synthesis,Antimyeloproliferative Activity Evaluation, and Molecular Docking. PHARMACEUTICALS , v. 15, p. 309-332, 2022. 
• FARIA, JESSICA V. ; PASSOS, FERNANDA PZ ; DA COSTA, PAULO HA ; DE OLIVEIRA, ANDRESSA P. ; DA CRUZ, YASMIN OD ; CASTELO-BRANCO, FREDERICO S. ; LOURENÇO, MARIA CS ; MURTA, SILVANE MF ; JUNIOR, POLICARPO AS ; BERNARDINO, ALICE MR ; Bastos, Monica M. ; Boechat, Nubia . Novel 2-Nitroimidazole and Imidazooxazole Derivatives and their Activity against Trypanosoma cruzi and Mycobacterium tuberculosis. Medicinal Chemistry , v. 18, p. 701-709, 2022. 
• REIS, CAROLINE RODRIGUES CHAVES DOS ; SOUZA, HELLEN VALÉRIO CHAVES MOURA DE ; LEME, RENNAN PAPALEO PAES ; CASTELO-BRANCO, FREDERICO SILVA ; FERNANDES, TÁCIO VINÍCIO AMORIM ; Boechat, Núbia ; DIAS, LUIZA ROSARIA SOUSA ; HOELZ, LUCAS VILLAS BÔAS . Study of the dynamic behavior of the cruzain enzyme in free and complexed forms with competitive and noncovalent benzimidazole inhibitors. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , v. 2022, p. 1-15, 2022
• GIACOLETTI, GIANNA ; PRICE, TATUM ; Hoelz, Lucas VB ; SHREMO MSDI, ABDULWHAB ; COSSIN, SAMANTHA ; VAZQUEZ-FALTO, KATERINA ; AMORIM FERNANDES, TÁCIO V. ; SANTOS DE PONTES, VINÍCIUS ; WANG, HONGBING ; Boechat, Nubia ; NORNOO, ADWOA ; BRUST, TARSIS F. . A Selective Adenylyl Cyclase 1 Inhibitor Relieves Pain Without Causing Tolerance. Frontiers in Pharmacology , v. 13, p. 1-12, 2022. 
• The Use of Zidovudine Pharmacophore in Multi-Target- Directed Ligands for AIDS Therapy. MOLECULES , v . 27, p. 8502, 2022. 
• SILVEIRA, FLÁVIA F. ; DE SOUZA, JULIANA O. ; HOELZ, LUCAS VB ; CAMPOS, VINÍCIUS R. ; JABOR, VALQUÍRIA AP ; AGUIAR, ANNA CC ; NONATO, M. CRISTINA ; Albuquerque, Magaly G. ; GUIDO, RAFAEL VC ; Boechat, Nubia ; Pinheiro, Luiz CS . Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , v. 209, p. 112941, 2021. 
• SOUZA, AAA ; TORRES, LR ; CAPOBIANCO, LRPL ; PAULA, VS ; CASCABULHO, CM ; SALOMAO, K. ; BONECINI-ALMEIDA, MG ; Ferreira, Maria de Lourdes G. ; BOECHAT, N. ; PINHEIRO, LUIZ CS ; SOUZA, EM . Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells. Viruses-Basel , v. 13, p. 36, 2021.
• SACRAMENTO, CAROLINA Q ; FINTELMAN-RODRIGUES, NATALIA ; TEMEROZO, JAIRO R ; SILVA, ALINE DE PAULA DIAS ; DIAS, SUELEN DA SILVA GOMES ; SILVA, CARINE DOS SANTOS ; FERREIRA, ANDRE C ; MATTOS, MAYARA ; BREAD, CAMILA RR ; FREITAS, CAROLINE S ; SOARES, VINICIUS CARDOSO ; HOELZ, LUCAS VILLAS BÔAS ; FERNANDES, TÁCIO VINÍCIO AMORIM ; BRANCO, FREDERICO SILVA CASTELO ; BASTOS, MONICA MACEDO ; BOECHAT, Núbia ; SARAIVA, FELIPE B ; FERREIRA, MARCELO ALVES ; JOCKUSCH, STEFFEN ; WANG, XUANTING; et.al. antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY , v. 76, p. 1874-1885, 2021.
• FERREIRA PIMENTEL, LUIZ CLAUDIO ; Hoelz, LVB ; CANZIAN, HENAYLE FERNANDES ; BRANCO, FSC ; OLIVEIRA, AP ; CAMPOS, VR ; S JUNIOR, FP ; DANTAS, RF ; RESENDE, JALC ; CUNHA, AC ; BOECHAT, N. ; BASTOS, MM . (Phenylamino)pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia. Beilstein Journal of Organic Chemistry , v. 17, p. 2260-2269, 2021. 
• BIANCO, MCAD; Milk, DI; Hoelz, L. B.; Bastos, Monica M. ; BOECHAT, N. . Pyrroles as Privileged Scaffolds in the Search for New Potential HIV Inhibitors. PHARMACEUTICALS , vol. 14, p. 893, 2021.
• FRANÇA, RODOLFO RODRIGO FLORIDO ; MENOZZI, CHEYENE ALMEIDA CELESTINO ; CASTELO-BRANCO, FREDERICO SILVA ; HOELZ, LUCAS VILLAS BÔAS ; Boechat, Nubia . The medicinal chemistry of 3-nitro-1,2,4-triazoles: focus on infectious diseases. CURRENT TOPICS IN MEDICINAL CHEMISTRY , v. 21, p. 2072-2100, 2021. 
• COUTINHO, JULIA PENNA ; DA SILVA ARAÚJO, MAISA ; CAMPOS AGUIAR, ANNA CAROLINE ; SÁ, PAULA MIRANDA ; RIOS, CARLOS TONG ; MEDEIROS, JANSEN FERNANDES ; PEREIRA, DHÉLIO BATISTA ; Boechat, Nubia ; Krettli, Antoniana Ursine . MEFAS, a hybrid of artesunate-mefloquine active against asexual stages of Plasmodium vivax in field isolates, inhibits malaria transmission. International Journal for Parasitology-Drugs and Drug Resistance , v. 17, p. 150-155, 2021. 
• DO PRADO, VÂNIA MENDES ; QUEIROZ, THIAGO BRANQUINHO ; SÁ, PAULA M. ; SEICEIRA, RAFAEL CARDOSO ; BOECHAT, N. ; FERREIRA, FABIO FURLAN . Mechanochemistry for the production of a hybrid salt used in the treatment of malaria. GREEN CHEMISTRY , v. 22, p. 51-61, 2020. 
• ROGERIO, KAMILLA RODRIGUES ; GRAEBIN, CEDRIC STEPHAN ; PINTO DOMINGUES, LUIZA HELENA ; OLIVEIRA, LUANA SANTOS ; DE SOUZA FERNANDES DA SILVA, VITORIA ; DANIEL-RIBEIRO, CLAUDIO TADEU ; CARVALHO, LEONARDO JM ; Boechat, Nubia . Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum. CURRENT TOPICS IN MEDICINAL CHEMISTRY , v. 20, p. 99-110, 2020. 
• FERREIRA PIMENTEL, LUIZ CLAUDIO ; CUNHA, ANNA CLAUDIA ; BOAS HOELZ, LUCAS VILLAS ; CANZIAN, HENAYLE FERNANDES ; LEITE FIRMINO MARINHO, DEBORA INACIO ; Boechat, Nubia ; Bastos, Monica Macedo . Phenylamino-pyrimidine (PAP) privileged structure: Synthesis and medicinal applications. CURRENT TOPICS IN MEDICINAL CHEMISTRY , v. 20, p. 227-243, 2020. 
• P2X7 receptor inhibition by 2-amino-3-aryl- 1,4-naphthoquinones. BIOORGANIC CHEMISTRY , v. 104, p. 104278-104289, 2020. 
• Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , v . 186 , p . 111887-111902, 2020. 
• PINHEIRO, LCS ; Hoelz, LVB ; Ferreira, MLG ; Oliveira, LG ; PEREIRA, RFA ; VALLE, AM ; ANDRÉ, LSP ; SCAFFO, J. ; PINHEIRO, FR ; RIBEIRO, TAN ; SACHS, D. ; PASCOAL, ACRF ; BOECHAT, N. ; AGUIAR'ALVES, F. . Synthesis of benzoylthiourea derivatives and analysis of their antibacterial performance against planktonic Staphylococcus aureus and its biofilms. LETTERS IN APPLIED MICROBIOLOGY , v. 71, p. 645-651, 2020. 
• Boechat, Nubia ; CARVALHO, RITA CC ; Ferreira, Maria de Lourdes G. ; COUTINHO, JULIA PENNA ; Sa, Paula M. ; SEITO, LEONARDO N. ; ROSAS, ELAINE C. ; Krettli, Antoniana U. ; Bastos, Monica M. ; Pinheiro, Luiz CS . Antimalarial and anti-inflammatory activities of new chloroquine and primaquine hybrids: Targeting the blockade of malaria parasite transmission. BIOORGANIC & MEDICINAL CHEMISTRY, v. 28, p. 115832, 2020. 
• FREITAS, CAROLINE S. ; HIGA, LUIZA M. ; SACRAMENTO, CAROLINA Q. ; FERREIRA, ANDRÉ C. ; REIS, PATRICIA A. ; DELVECCHIO, RODRIGO ; MONTEIRO, FABIO L. ; BARBOSA-LIMA, GISELLE ; JAMES WESTGARTH, HARRISON ; VIEIRA, YASMINE RANGEL ; MATTOS, MAYARA ; ROCHA, NATASHA ; HOELZ, LUCAS VILLAS BÔAS ; LEME, RENNAN PAPALEO PAES ; BASTOS, MONICA M. ; L. RODRIGUES, GISELE OLINTO ; M. LOPES, CARLA ELIZABETH ; QUEIROZ-JUNIOR, CELSO MARTINS ; LIMA, CRISTIANO X. ; BOECHAT, N. ; et.al. Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo. PLoS Neglected Tropical Diseases , v. 13, p. e0007072, 2019. 
• DA SILVA, RENATA MRJ ; GANDI, MARILIA O. ; MENDONÇA, JORGE S. ; CARVALHO, ALCIONE S. ; COUTINHO, JULIA PENNA ; AGUIAR, ANNA CC ; Krettli, Antoniana U. ; Boechat, Nubia . New hybrid trifluoromethylquinolines as antiplasmodium agents. BIOORGANIC & MEDICINAL CHEMISTRY , v. 27, p. 1002-1008, 2019. 
• GONZAGA, DTG ; OLIVEIRA, FH ; SALLES, JP ; BELLO, ML ; RODRIGUES, CR ; CASTRO, HC ; SOUZA, H. ; REIS, C. ; LEME, R. ; MAFRA, JCM ; Pinheiro, LCS ; BOECHAT, N. ; FARIA, RX . Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors. Frontiers in Chemistry , v. 7, p. 1-15, 2019.
• FERREIRA, ANDRÉ C. ; REIS, PATRICIA A. ; FREITAS, CAROLINE S. ; SACRAMENTO, CAROLINA Q. ; VILLAS BÔAS HOELZ, LUCAS ; BASTOS, MONICA M. ; MATTOS, MAYARA ; ROCHA, NATASHA ; GOMES DE AZEVEDO QUINTANILHA, ISACLAUDIA ; PEDROSA, CAROLINA ; ROCHA QUINTINO SOUZA, LETICIA ; CORREIA LOIOLA, ERICK ; TRINDADE, PABLO ; RANGEL VIEIRA, YASMINE ; BARBOSA-LIMA, GISELLE ; BÜNING, KARIN ; BOZZA, FERNANDO A. ; et.al. Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (ONLINE) , v. 63, p. e01389-18, 2019. 
• VENÂNCIA, TIAGO; OLIVEIRA, LYEGE MAGALHAES ; PAWLAK, TOMASZ ; ELLENA, JAVIER ; Boechat, Nubia ; BROWN, STEVEN P. . The use of variable temperature 13 C solid-state MAS NMR and GIPAW DFT calculations to explore the dynamics of diethylcarbamazine citrate. MAGNETIC RESONANCE IN CHEMISTRY , v. 57, p. 200-208, 2019. 
• Safety assessment of MEFAS: an innovative hybrid salt of mefloquine and artesunate for malaria treatment. DRUG AND CHEMICAL TOXICOLOGY , v. 42, p. 1-6, 2019. 
• FEITOSA, LIVIA M. ; DA SILVA, EDSON R. ; HOELZ, LUCAS VB ; SOUZA, DANIELLE L. ; COME, JULIO AASS ; CARDOSO-SANTOS, CAMILA ; BATISTA, MARCOS M. ; SOEIRO, MARIA DE NAZARE C. ; Boechat, Nubia ; Pinheiro, Luiz CS . New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY , v. 27, p. 3061-3069, 2019. 
• SIMÕES-SILVA, MR ; DE ARAÚJO, JS ; PERES, RB ; DA SILVA, PB ; BATISTA, MM ; DE AZEVEDO, LD ; BASTOS, MM ; BAHIA, MT ; BOECHAT, N. ; SOEIRO, MNC . Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi. PARASITOLOGY , v. 146, p. 1-7, 2019. 
• VON TROMPOWSKY, ANA CLAUDIA MANOEL ; CONDE, TALINE RAMOS ; LEMOS, RENATA CALIL ; QUARESMA, BRUNA MARIA CS ; PITOMBEIRA, MARCELLY CRISTINA SR ; DE CARVALHO, ALCIONE SILVA ; Boechat, Núbia ; SALOMÃO, KELLY ; DE CASTRO, SOLANGE LISBOA ; ZAMITH, HELENA PEREIRA DA SILVA . In vitro genotoxicity of nitroimidazoles as a tool in the search for new trypanocidal agents. Memoirs of the Oswaldo Cruz Institute , v. 114, p. 1-10, 2019. 
• PINHEIRO, LUIZ CS ; de Lourdes G. Ferreira, Maria ; SILVEIRA, FLÁVIA F. ; FEITOSA, LÍVIA M. ; Boechat, Nubia . Synthetic compounds with sulfonamide moiety against Leishmaniasis: an overview. MEDICINAL CHEMISTRY RESEARCH , v. 28, p. 1807-1817, 2019. 
• CRIZANTO DE LIMA, EVANOEL ; CASTELO-BRANCO, FREDERICO S. ; MAQUIAVELI, CLAUDIA C. ; FARIAS, ANDRÉ B. ; RENNÓ, MAGDALENA N. ; Boechat, Nubia ; SILVA, EDSON R. . Phenylhydrazides as inhibitors of Leishmania amazonensis arginase and antileishmanial activity. BIOORGANIC & MEDICINAL CHEMISTRY , v. 27, p. 3853-3859, 2019. 
• CS PINHEIRO, LUIZ ; M. FEITOSA, LÍVIA ; O. GANDI, MARILIA ; F. SILVEIRA, FLÁVIA ; Boechat, Nubia . The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines. MOLECULES , v. 24, p. 4095, 2019. 
• BOECHAT, NÚBIA A ; Magalhães JL ; Zulmira Hartz ; Marlede Menezes ; MENDONÇA, JORGE S. . An overview of antibiotics in Brazil: a sovereign been lost of the amoxicillin. CHIMICA OGGI-CHEMISTRY TODAY, v. 37, p. 73, 2019.
• CASTELO-BRANCO, FREDERICO SILVA ; DE LIMA, EVANOEL CRIZANTO ; DE OLIVEIRA DOMINGOS, JORGE LUIZ ; Pinto, Angelo C. ; LOURENÇO, MARIA CRISTINA S. ; GOMES, KAREN MACHADO ; COSTA-LIMA, MARIANA MARQUES ; ARAUJO-LIMA, CARLOS FERNANDO ; AIUB, CLAUDIA ALESSANDRA FORTES ; FELZENSZWALB, ISRAEL ; COSTA, THADEU ESTEVAM MM ; PENIDO, CARMEN ; HENRIQUES, MARIA G. ; Boechat, Nubia . New hydrazide derivatives of isoniazid against Mycobacterium tuberculosis: Higher potency and lower hepatocytotoxicity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , v. 15, n. 2, p. 146, p. 529-540, 2018. 
• BOECHAT, N. ; Pinheiro, Luiz CS ; FEITOSA, LM ; SILVEIRA, FF . Current Antimalarial Therapies and Advances in the Development of Semi-Synthetic Artemisinin Derivatives. ANNALS OF THE BRAZILIAN ACADEMY OF SCIENCES (ONLINE), v. 90, p. 1251-1271, 2018. 
• SILVEIRA, FLÁVIA F. ; FEITOSA, LÍVIA M. ; MAFRA, JOÃO CM ; Ferreira, Maria de Lourdes G. ; ROGERIO, KAMILLA R. ; CARVALHO, LEONARDO JM ; Boechat, Nubia ; PINHEIRO, LUIZ CS . Synthesis and anti-Plasmodium falciparum evaluation of novel pyrazolopyrimidine derivatives. MEDICINAL CHEMISTRY RESEARCH , v. 27, p. 1876-1884, 2018. 
• HOELZ, LUCAS VB ; CALIL, FELIPE A ; NONATO, MARIA C ; PINHEIRO, LUIZ CS ; Boechat, Nubia . Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria. Future Medicinal Chemistry , v. 10, p. 1853-1874, 2018. 
• COSTA, CAROLINA CP ; Boechat, Nubia ; Bastos, Monica M. ; da Silva, Fernando de C. ; MARTTORELLI, ANDRESSA ; SOUZA, THIAGO ML ; BAPTISTA, MAYARA S. ; HOELZ, LUCAS VB ; CAFFFARENA, ERNESTO R. . New Efavirenz Derivatives and 1,2,3-Triazolyl-phosphonates as Inhibitors of Reverse Transcriptase of HIV-1. CURRENT TOPICS IN MEDICINAL CHEMISTRY , v. 18, p. 1494-1505, 2018. 
• New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations. Chemical Biology & Drug Design , v. 15, n. 2 , p . 92, p. 1670-1682, 2018. 
• Azeredo, LFSP ; PENNA-COUTINHO, J. ; JABOR, VAP ; FELICIANO, PR ; NONATO, MC ; kaiser, CR ; MENEZES, CMR ; HAMMES, ASO ; CAFFARENA, ER ; Hoelz, Lucas VB ; SOUZA, NB ; PEREIRA, GAN ; Ceravolo, IP ; Krettli, Antoniana U. ; BOECHAT, N. . Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors. European Journal of Medicinal Chemistry , v. 126, p. 72-83, 2017. 
• SACRAMENTO, CAROLINA Q. ; MELO, GABRIELLE R. ; FREITAS, CAROLINE S. ; ROCHA, NATASHA ; HOELZ, LUCAS VILLAS BÔAS ; MIRANDA, MILENE ; FINTELMAN-RODRIGUES, NATALIA ; MARTTORELLI, ANDRESSA ; FERREIRA, ANDRÉ C. ; BARBOSA-LIMA, GISELLE ; ABRANTES, JULIANA L. ; VIEIRA, YASMINE RANGEL ; BASTOS, MONICA M. ; NUNES, ESTEVÃO PORTELA ; TSCHOEKE, DIOGO A. ; LEOMIL, LUCIANA ; LOIOLA, ERICK CORREIA ; TRINDADE, PABLO ; BOECHAT, N. ; et.al . The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication. Scientific Reports , vol. 7, p. 40920, 2017. 
• BOECHAT, N. ; BRANCO, FSC ; FRANÇA, RODOLFO RODRIGO F. ; JL Domingos ; Menozzi, CAC . Optimization of Fluconazole Synthesis: An Important Azole Antifungal Drug. VIRTUAL JOURNAL OF CHEMISTRY, v. 9, p. 1216-1234, 2017. 
• Boechat, Nubia ; BASTOS, MÔNICA MACEDO ; DE AZEVEDO, LIVIANE DIAS ; DE OLIVEIRA, ANDRESSA PAULA . Synthesis and properties of BCR-ABL tyrosine kinase inhibitor drugs used in the treatment of Chronic Myeloid Leukemia. QUÍMICA NOVA (ONLINE), v. XY, p. 01-19, 2017. 
• DE AZEVEDO, LIVIANE DIAS ; BASTOS, MM ; VASCONCELOS, F. ; Hoelz, Lucas VB ; S JUNIOR, FP ; DANTAS, RF ; ALMEIDA, ACM ; OLIVEIRA, AP ; GOMES, LC ; MAIA, RC ; BOECHAT, N. . Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia. MEDICINAL CHEMISTRY RESEARCH , v. 26, p. 2929-2941, 2017. 
• FARIA, JÉSSICA VENÂNCIA ; VEGI, PERCILENE FAZOLIN ; MIGUITA, ANA GABRIELLA CARVALHO ; DOS SANTOS, MAURÍCIO SILVA ; Boechat, Nubia ; BERNARDINO, ALICE MARIA ROLIM . Recently Reported Biological Activities of Pyrazole Compounds. BIOORGANIC & MEDICINAL CHEMISTRY , v. 25, p. 5891-5903, 2017. 
• VENÂNCIO, TIAGO ; OLIVEIRA, LYEGE MAGALHAES ; ELLENA, JAVIER ; Boechat, Nubia ; BROWN, STEVEN P. . Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS 1 H solid-state NMR spectroscopy and GIPAW calculations. SOLID STATE NUCLEAR MAGNETIC RESONANCE , v. 87, p. 73-79, 2017. 
• SACRAMENTO, CAROLINA Q. ; MELO, GABRIELLE R. ; FREITAS, CAROLINE S. ; ROCHA, NATASHA ; HOELZ, LUCAS VILLAS BÔAS ; MIRANDA, MILENE ; FINTELMAN-RODRIGUES, NATALIA ; MARTTORELLI, ANDRESSA ; FERREIRA, ANDRÉ C. ; BARBOSA-LIMA, GISELLE ; ABRANTES, JULIANA L. ; VIEIRA, YASMINE RANGEL ; BASTOS, MONICA M. ; VOLOTÃO, EDUARDO DE MELLO ; NUNES, ESTEVÃO PORTELA ; TSCHOEKE, DIOGO A. ; LEOMIL, LUCIANA ; LOIOLA, ERICK CORREIA ; TRINDADE, PABLO ; BOECHAT, N. ; et.al . Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication. Scientific Reports , v. 7, p. 46772, 2017. 
• Boechat, Núbia ; BASTOS, MM ; COSTA, CCP ; BEZERRA, TC ; SILVA, FC . Efavirenz a nonnucleoside reverse transcriptase inhibitor of first-generation: Approaches based on its medicinal chemistry. European Journal of Medicinal Chemistry, v. 108, p. 455-465, 2016. 
• PENNA-COUTINHO, J.; ALMELA, M.; MIGUEL-BLANCO, C.; HERREROS, E. ; SA, PM ; BOECHAT, N .; Krettli, Antoniana Ursine. Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and Mefloquine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , v. 60, p. 3145-3147, 2016. 
• Carvalho, Rita de CC ; MARTINS, WA ; SILVA, TP ; kaiser, CR ; BASTOS, MM ; PINHEIRO, LUIZ CS ; KRETTLI, AU ; BOECHAT, NÚBIA A . New Pentasubstituted Pyrrole Hybrid Atorvastatin-Quinoline Derivatives with Antiplasmodial Activity. Bioorganic & Medicinal Chemistry Letters (Print) , p. 1881-1884, 2016. 
• AYALA, AP ; Honorato, SB ; Da Silva, C. C, Pinheiro ; MENDONCA, JS ; BOECHAT, NÚBIA A ; J. Ellena . On the Thermal Stability of the Diethylcarbamazine-Fortified Table Salt Used in the Control of Lymphatic Filariasis. Journal of Pharmaceutical Sciences , v. 105, p. 2437-2443, 2016. 
• Boechat, Nubia ; CARVALHO, ALCIONE S. ; QUARESMA, BRUNA MCS; Wardell, James L.; Wardell, Solange MSV . 4-Cyclopropyl-1-(1-methyl-4-nitro-1H-imidazol-5-yl)-1H-1,2,3-triazole and Ethyl 1-(1-methyl-4-nitro-1H-imidazol-5-yl)-1H-1,2,3-triazole-4-carboxylate. Journal of Chemical Crystallography, vol. 2016, p. 1-7, 2016. 
• SILVA, THAIS B. ; BERNARDINO, ALICE MR ; Ferreira, Maria de Lourdes G. ; ROGERIO, KAMILLA R. ; CARVALHO, LEONARDO JM ; Boechat, Nubia ; Pinheiro, Luiz CS . Design, synthesis and anti-P. falciparum activity of pyrazolopyridine-sulfonamide derivatives. Bioorganic & Medicinal Chemistry (Print) , v. 24, p. 4492-4498, 2016. 
• BOECHAT, N. ; BASTOS, MM ; Hoelz, LVB ; OLIVEIRA, AP . Antileishmanial Chemotherapy: A Literature Review. Virtual Journal of Chemistry, v. 8, p. 2072-2104, 2016. 
• Magalhães JL ; QUONIAM, L. ; BOECHAT, N. . La proprieté industrielle dans le cancer et le droit à la vie: cas de l'intelligence économique au Brésil associé à la tuberculosis. Revue Internationale d'Intelligence Économique, v. 7, p. 47-61, 2015.
• Costa, Carolina CP ; Boechat, Núbia ; da Silva, Fernando de Carvalho ; Rosario, Sandra L. ; BEZERRA, TC ; Bastos, Monica Macedo . The Efavirenz: Structure-Activity Relationship and Synthesis Methods. Virtual Journal of Chemistry , v. 7, p. 1347-1370, 2015. 
• CARVALHO, ALCIONE S. DE ; DUARTE, SILVIO LUIZ ; COSTA, JORGE CARLOS S. DA ; Boechat, Núbia . A New Process for Obtaining Meglumine Antimoniate Aiming at the Production of Generic Drug. Virtual Journal of Chemistry , v. 7, p. 684-696, 2015. 
• Anti - Plasmodium falciparum activity of quinoline - sulfonamide hybrids. Bioorganic & Medicinal Chemistry ( Print) , v. 23, p. 5979-5984, 2015. 
• Boechat, Núbia ; Bastos, Monica Macedo . SELECTIVE FLUORINATION METHODS OF ORGANIC MOLECULES. Química Nova (Print), v. 38, p. 1323-1338, 2015. 
• BRANCO, FSC ; SILVA, BV ; RIO, GF ; SANTANA, MJ ; QUEIROZ JUNIOR, LHK ; Pinto, Angelo C. ; LIAO, LM ; Boechat, Núbia . NUCLEAR MAGNETIC RESONANCE OF ORGANOFLUORINATED SUBSTANCES: A CHALLENGE IN SPECTROSCOPY TEACHING. Química Nova (Print), v. 38, p. 1237-1246, 2015. 
• Leite, DI ; AZEVEDO, LD ; FARIAS, JV ; FIGUEIREDO, YV ; MARTINS, WA ; BIANCO, MCAD ; BERNARDINO, AMR ; BASTOS, MÔNICA M. ; Boechat, Núbia . Tenofovir: Structure-Activity Relationship and Synthesis Methods. Virtual Journal of Chemistry, v. 7, p. 2347-2376, 2015. 
• DA SILVA, EDSON R. ; Boechat, Nubia ; PINHEIRO, LUIZ CS ; Bastos, Monica M. ; Costa, Carolina CP ; BARTHOLOMEU, JULIANA C. ; DA COSTA, TALITA H. . Novel Selective Inhibitor of Leishmania (Leishmania) amazonensis Arginase. Chemical Biology & Drug Design (Print), v. 86, p. n/an/a, 2015. 
• Boechat, Núbia ; CARVALHO, ALCIONE S ; SALOMÃO, KELLY ; CASTRO, SOLANGE L DE ; ARAUJO-LIMA, CARLOS F ; MELLO, FRANCISCO VC ; FELZENSZWALB, ISRAEL ; AIUB, CLAUDIA AF ; CONDE, TALINE RAMOS ; ZAMITH, HELENA PS ; SKUPIN, ROLF ; HAUFE, GÜNTER . Studies of genotoxicity and mutagenicity of nitroimidazoles: demystifying this critical relationship with the nitro group. Memórias do Instituto Oswaldo Cruz, v. 110, p. 492-499, 2015. 
• HONORATO, SB ; MENDONCA, JS ; Boechat, Núbia ; OLIVEIRA, AC ; Mendes Filho, J. ; J. Ellena ; AYALA, AP . Novel polymorphs of the anti-Trypanosoma cruzi drug benznidazole. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy (Print), v. 118, p. 389-394, 2014. 
• CARVALHO, ALCIONE SILVA DE ; SALOMÃO, KELLY ; CASTRO, SOLANGE LISBOA DE ; CONDE, TALINE RAMOS ; ZAMITH, HELENA PEREIRA DA SILVA ; CAFFARENA, ERNESTO RAÚL ; HALL, BELINDA SUZETTE ; WILKINSON, SHANE ROBERT ; Boechat, Núbia . Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme. Memórias do Instituto Oswaldo Cruz (Print), v. 1-9, p. 315-323, 2014. 
• FRANÇA, RODOLFO RODRIGO F. ; CARVALHO, ALCIONE S. DE ; BRANCO, FREDERICO SC ; Pinto, Angelo C. ; Boechat, Núbia . Potent Inhibitors of the Enzyme Sterol 14α-demethylase Against. Virtual Journal of Chemistry, v. 6, p. 1483-1516, 2014. 
• LOURDES G. FERREIRA, MARIA ; PINHEIRO, LCS ; SANTOS-FILHO, OSVALDO A. ; PEÇANHA, MARTA DS ; SACRAMENTO, CAROLINA Q. ; MACHADO, VIVIANE ; FERREIRA, VITOR F. ; SOUZA, THIAGO MORENO L. ; BOECHAT, N. . Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs. Medicinal Chemistry Research (Print), v. 23, p. 1501-1511, 2014. 
• Boechat, Núbia ; Ferreira, Maria de Lourdes G. ; PINHEIRO, LUIZ CS ; JESUS, ANTÔNIO ML ; LEITE, MILENE MM ; JUNIOR, CARLOS CS ; AGUIAR, ANNA CC ; DE ANDRADE, ISABEL M. ; Krettli, Antoniana U. . New Compounds Hybrids 1 H -1,2,3-Triazole-Quinoline Against Plasmodium falciparum. Chemical Biology & Drug Design, v. 84, p. 325-332, 2014. 
• Boechat, Nubia ; Pinheiro, Luiz CS ; Pinto, Angelo C .; SILVA, THIAGO S. ; Wardell, James L.; WARDELL, SOLANGE MSV . Crystal structures of two anhydrous and one hydrated 7-(arylamino)-5-methyl-2-(trifluoromethyl)-[1,2,4]-triazolo-[1,5-a]pyrimidine derivatives. ZEITSCHRIFT FOR KRISTALLOGRAPHIE - CRYSTALLINE MATERIALS, v. 229, p. 459-471, 2014. 
• FERRREIRA, VF ; ROCHA, D. ; SILVA, F. ; FERREIRA, P. ; BOECHAT, N. ; Magalhães JL . Novel 1 -1,2,3-, 2 -1,2,3-, 1 -1,2,4- and 4 -1,2,4-triazole derivatives: a patent review (2008 ¿ 2011). Expert Opinion on Therapeutic Patents , v. 23, p. 319-331, 2013. 
• BOECHAT, N. ; BASTOS, MM ; DUARTE, SL ; COSTA, J. ; MAFRA, JCM ; DANIEL, LCC . Imatinib Mesylate: An Optimization in its Synthesis. VIRTUAL JOURNAL OF CHEMISTRY, v. 5, p. 222-234, 2013. 
• BASTOS, MM ; GOMES, ATPC ; NEVES, MGPMS; SILVA, AMS ; Santos-Filho, OA ; BOECHAT, N .; Knight, JAS. Synthesis of β-Substituted Porphyrin Derivatives Containing Heterocyclic Moieties as Potential Photosensitizers Against Cutaneous Leishmaniasis. European Journal of Organic Chemistry (Print), vol. 2013, p. 1485-1493, 2013. 
• Boechat, Núbia ; Bastos, Monica Macedo . Fluorinated Compounds Against Mycobacterium tuberculosis. Current Topics in Medicinal Chemistry (Print), v. 13, p. 2885-2904, 2013. 
• BRANCO, FSC ; Pinto, Angelo C. ; Boechat, Núbia . An Update on the Chemistry and Medicinal Chemistry of Novel Antimycobacterial Compounds. Current Topics in Medicinal Chemistry (Print), v. 13, p. 2808-2849, 2013. 
• Magalhães JL ; QUONIAM, L. ; Boechat, Nubia ; KENAP, AA. Neglected illness in social networks? A blueprint of Dengue in twitter as a contribution of information science for public health. International Journal of Management, IT and Engineering, v. 3, p. 194-204, 2013.
• BOECHAT, N. ; Magalhães JL ; QUONIAM, L. . Web 2.0 Tools for Network Management and Patent Analysis for Public Health. Electronic Journal Management & Health, v. 02, p. 26-41, 2013. 
• BOECHAT, N .; Magalhães JL ; QUONIAM, L.; FERREIRA, VF ; FERREIRA, P. . Research on pharmaceuticals patents in times of Big data: a contribution of the Web 2.0 for medicinal chemistry.. Intellectual Properties Rights: Open Access, v. 13, p. 01-09, 2013.
• BOECHAT, N .; LAGES, AS ; BASTOS, MM ; GENESTRA, MS ; Santos-Filho, OA ; Kover, WB. Synthesis of Simple Molecules Prepared as Arginase Inhibitors and Evaluated Against Leishmania amazonensis.. Journal of Microbiology and Antimicrobials, v. 05, p. 72-86, 2013.
• MELLO, FRANCISCO VC ; CARVALHO, ALCIONE S. ; BASTOS, MÔNICA M. ; Boechat, Nubia ; Aiub, Claudia AF ; FELZENSZWALB, ISRAEL . Evaluation of Genotoxic Effects of New Molecules with Possible Trypanocidal Activity for Chagas Disease Treatment. THE SCIENTIFIC WORLD JOURNAL, v. 2013, p. 1-8, 2013. 
• BOECHAT, N. ; Magalhães JL ; ANTUNES, A. . Internalization of pharmaceutical chemicals and medicines for neglected tropical diseases: proposal for interaction between Government - University - Business. Química Nova (Print), v. 35, p. 654-660, 2012
• Magalhães JL ; BOECHAT, N. ; ANTUNES, A. . Identification of Brazilian expertise in the fight against some neglected tropical diseases. Journal of the Brazilian Society of Tropical Medicine (Print), v. 45, p. 415-417, 2012. 
• BASTOS, MM ; BOECHAT, N. ; Gomes, ATPC ; Neves, MGPM ; Cavaleiro, JAS . The Use of Porphyrins in Photodynamic Therapy of Cutaneous Leishmaniasis. VIRTUAL JOURNAL OF CHEMISTRY, v. 4, p. 257-267, 2012. 
• Santos-Filho, Osvaldo A. ; Forge, Delphine ; Hoelz, Lucas VB ; Freitas, Guilherme BL ; Marinho, Thiago O. ; Araújo, Jocley Q. ; Albuquerque, Magaly G. ; Alencastro, Ricardo B. ; BOECHAT, N. . CoMFA/CoMSIA 3D-QSAR of pyrimidine inhibitors of Pneumocystis carinii dihydrofolate reductase. Journal of Molecular Modeling, v. 2012, p. on line-on line, 2012. 
• Boechat, Nubia ; by Lourdes G. Ferreira, Maria; Bastos, Monica M .; da Silva, Gerson P.; Wardell, Solange MSV; Wardell, James . Structures of 1-(substituted-phenyl)-4-hydroxymethyl- and -4-fluoromethyl-1,2,3-triazoles. Zeitschrift fur Kristallographie, vol. 227, p. 369-378, 2012. 
• BOECHAT, N. ; BRANCO, FSC ; PINTO, AC . The Medicinal Chemistry of Novel Molecules in Clinical Trials for Tuberculosis Treatment. VIRTUAL JOURNAL OF CHEMISTRY, v. 4, p. 287-328, 2012. 
• BOECHAT, N. ; Pinheiro, LCS . Leprosy and its Chemotherapy. VIRTUAL JOURNAL OF CHEMISTRY, v. 4, p. 247-256, 2012.
• BOECHAT, N. ; Pinheiro, LCS ; SILVA, TS ; Aguiar, AC ; CARVALHO, AS ; BASTOS, MM ; COSTA, CCP ; Pinheiro,S. ; PINTO, AC ; MENDONCA, JS ; KDB Dutra ; VALVERDE, AL ; Santos-Filho, OA ; KRETTLI, AU . New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodium falciparum Agents. Molecules (Basel. Online), v. 17, p. 8285-8302, 2012. 
• WOLLINGER, W. ; LESSA, BM ; NOBREGA, AB ; RIENTE, RR ; SABATINI, R. ; LOPES, CC ; BOECHAT, N. ; SLANA, GBCA . Simultaneous Determination of Assay and Related Substances in Nevirapine Suspension by HPLC. Chromatographia (Wiesbaden) , v. 75, p. 893-901, 2012. 
• BOECHAT, N .; Wardell, J.L .; Wardell, Solange MSV; BASTOS, MM . Structures of two N-{2-([(5-amino-1,3,4-thiadiazol-2-yl)difluoromethyl]-4-halophenyl}acetamides. Journal of Chemical Crystallography, v. 41, p. 874-879, 2011. 
• Magalhães JL ; ANTUNES, A. ; BOECHAT, N. . Official pharmaceutical laboratories and their relevance for public health in Brazil. RECIIS. Electronic journal of communication, information & innovation in health (Portuguese edition. Online), v. 5, p. 367, 2011. 
• BOECHAT, N. ; Ferreira, Vitor F. ; Ferreira, Sabrina B. ; Ferreira, Maria de Lourdes G. ; da Silva, Fernando de C. ; Bastos, Monica M. ; Costa, Marilia dos S. ; Lourenc¿o, Maria Cristina S. ; Pinto, Angelo C. ; Krettli, Antoniana U. ; Aguiar, Anna Caroline ; Teixeira, Brunno M. ; da Silva, Nathalia V. ; Martins, Priscila RC ; Bezerra, Flavio Augusto FM ; Camilo, Ane Louise S. ; da Silva, Gerson P. ; Costa, Carolina CP . Novel 1,2,3-Triazole Derivatives for Use against Mycobacterium tuberculosis H37Rv (ATCC 27294) Strain. Journal of Medicinal Chemistry, v. 54, p. 5988-5999, 2011. 
• Boechat, Nubia ; Pinheiro, Luiz CS ; Santos-Filho, Osvaldo A. ; Silva, Isabor C. ; BOECHAT, N. . Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes. Molecules (Basel. Online), v. 16, p. 8083-8097, 2011. 
• BOECHAT, N .; Ferreira, Maria de Lourdes G .; BASTOS, MM ; Wardell, J.L .; Wardell, Solange MSV; Tiekink, E.R.T. [1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol hemihydrate. Acta Crystallographica. Section E, vol. E-67, p. 2934-2935, 2011. 
• BOECHAT, N .; LAGES, AS ; KOVER, WB ; Tiekink, E.R.T.; Wardell, J.L .; WARDELL, S. . N -(4-Chlorophenyl)-1,1,1-trifluoro- N -(trifluoromethylsulfonyl)methanesulfonamide. Acta Crystallographica. Section E, vol. 66, p. o506-o507, 2010. 
• BOECHAT, N. ; LAGES, AS ; KOVER, WB ; Tiekink, ERT ; Wardell, JL ; WARDELL, S. . 2-Chloro-6,6-dimethyl-5,6-dihydroindazolo[2,3- c ]quinazoline. ACTA CRYSTALLOGRAPHICA. SECTION E, v. 66, p. o521-o522, 2010. 
• BOECHAT, N .; BASTOS, MM . Trifluoromethylation of Carbonyl Compounds. CURRENT ORGANIC SYNTHESIS, v. 7, p. 403-413, 2010. 
• BOECHAT, N. ; KOVER, WB ; FERREIRA, SB ; WARDELL, S. ; Wardell, JL ; Tiekink, ERT . N -(4-Chlorophenyl)ethanimidamide. ACTA CRYSTALLOGRAPHICA. SECTION E, v. 66, p. o958-o958, 2010. 
• Da Silva, C. C, Pinheiro; Martins, FT; Honorato, SB ; BOECHAT, N .; AYALA, AP ; J. Ellena . Triple Structural Transition below Room Temperature in the Antifilarial Drug Diethylcarbamazine Citrate. CRYSTAL GROWTH & DESIGN , v. 10, p. 3094-3101, 2010. 
• Boechat, Nubia ; LG Ferreira, Maria ; Bastos, Monica M .; Camilo, Ane LS ; Wardell, Solange MSV; Wardell, James L.; Tiekink, Edward RT ; BOECHAT, N. . Crystal and Molecular Structures of Two Triazole Derivatives: 4-Cyclopropyl-4,5-dihydro-1H-1,2,3-triazole and Methyl 1-benzyl-1H-1,2,3-triazole-4-carboxylate. Journal of Chemical Crystallography, vol. 40, p. 1137-1141, 2010. 
• BOECHAT, N .; KOVER, WB ; BASTOS, MM ; PINTO, AC ; MACIEL, LC ; MAYER, LMU ; SILVA, FQ ; SA, PM ; MENDONCA, JS ; WARDELL, S.; ARRUDA, MS . N-Acyl-3,3-difluoro-2-oxoindoles as versatile intermediates for the preparation of different 2,2-difluorophenylacetic derivatives. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, v. 19, p. 445-457, 2008. 
• BOECHAT, N. ; COSTA, J. ; Neves JS ; SOUZA, MVN ; SIQUEIRA, RA ; NC Romeiro ; E Silva PMR ; MARTINS, MA . Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v. 18, p. 1162-1166, 2008. 
• BOECHAT, N. ; Magalhães JL ; ANTUNES, A. . An overview of the Brazilian Pharmaceutical Production Status. Chimica Oggi (Printed Text), v. 26, p. 24-25, 2008. 
• BOECHAT, N .; BASTOS, MM ; KOVER, WB ; MAYER, LMU ; CS, FE; SOARES, MC . Synthesis of new 3-(trifluoromethyl)-1 H -indoles by reduction of trifluoromethyloxoindoles. JOURNAL OF HETEROCYCLIC CHEMISTRY, v. 45, p. 969-973, 2008. 
• Magalhães JL ; BOECHAT, N .; ANTUNES, A. . MAIN CHALLENGES OF THE PUBLIC PRODUCTION OF MEDICATIONS IN BRAZIL Y. Revista Cubana de Salud Pública (Print), v. 34, p. 1-10, 2008.
• TEIXEIRA, EM ; RABELLO, A. ; BOECHAT, N. ; CARVALHO, AS ; COSTA, J. ; DUARTE, SL ; MENDONCA, JS . In vitro and in vivo activity of meglumine antimoniate produced at Farmanguinhos-Fiocruz, Brazil, against Leishmania (Leishmania) amazonensis, L (L.) chagasi and L (Viannia) braziliensis. MEMORIAS DO INSTITUTO OSWALDO CRUZ , v. 103, p. 358-362, 2008. 
• VAROTTI, FP ; ANDRADE, AA ; Paula, Renata C. de ; FAGUNDES, Elaine MS ; VALVERDE, AL ; MAYER, LMU ; MENDONCA, JS ; SOUZA, MVN ; BOECHAT, N .; KRETTLI, AU . Synthesis, Antimalarial Activity, and Intracellular Targets of MEFAS, a New Hybrid Compound Derived from Mefloquine and Artesunate. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v. 52, p. 3868-3874, 2008. 
• BOECHAT, N. ; CARVALHO, AS ; CASTRO, SL ; NC Romeiro . Design, Synthesis and Activity Against Trypanosoma cruzi of Azaheterocyclic Analogs of Megazol. Medicinal Chemistry, v. 3, p. 460-465, 2007. 
• KRETTLI, AU ; BOECHAT, N. ; SOUZA, MVN ; VASCONCELOS, TRA ; ANDRADE, AA ; VAROTTI, FP ; FREITAS, IO . Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 558, p. 194-198, 2007. 
• COSTA, MS ; BOECHAT, N .; WARDELL, S.; FERREIRA, V .; Low, JN; Glidewell, C. Three ethyl 5-amino-1-aryl-1 H -imidazole-4-carboxylates: hydrogen-bonded supramolecular structures in one, two and three dimensions. Acta Crystallographica Section C-Structural Chemistry, v. 63, p. o33-o37, 2007. 
• BOECHAT, N .; KOVER, WB ; BONGERTZ, V. ; BASTOS, MM ; NC Romeiro ; ML Guida; WOLLINGER, W. . Design, Synthesis and Pharmacological Evaluation of HIV-1 Reverse Transcriptase Inhibition of New Indolin-2-Ones. Medicinal Chemistry, vol. 3, p. 533-542, 2007. 
• BOECHAT, N .; KOVER, WB ; BASTOS, MM ; NC Romeiro ; VALVERDE, AL ; ML Guida; WOLLINGER, W. . Design, synthesis and biological evaluation of new 3-hydroxy-2-oxo-3-trifluoromethylindole as potential HIV-1 reverse transcriptase inhibitors. Medicinal Chemistry Research (Print), vol. 15, p. 492-507, 2007. 
• CUNICO, W. ; GOMES, CRB ; FERREIRA, ML ; Capri LR; BOECHAT, N .; BASTOS, MM ; MACIEL, LC ; MAYER, LMU . One-Pot Synthesis of 1,3-Thiazolidin-4-Ones Derivatives from 2-Amino-1,3,4-Thiadiazole. LETTERS IN ORGANIC CHEMISTRY, v. 4, p. 505-508, 2007. 
• BOECHAT, N. ; FERREIRA, SB ; COSTA, MS ; BEZERRA, RJ ; GENESTRA, MS ; CANTO-CAVALHEIRO, MM ; KOVER, WB ; FERREIRA, V. . Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 42, p. 1388-1395, 2007. 
• Boechat, Nubia ; LAGES, AS ; Santos-Filho, Osvaldo A. ; GENESTRA, MS ; Bastos, Monica Macedo ; KOVER, WB . Vibrational spectra and quantum mechanical calculations of antiretroviral drugs: Nevirapine. Journal of Molecular Structure (Print), v. 828, p. 201-210, 2007. 
• BOECHAT, N .; Alcione Silva Carvalho ; PINTO, AC ; GIBALDI, D .; BOZZA, M. . Synthesis and Trypanocidal Evaluation of News 5-[N-(3-(5-Substituted)- 1,3,4-Thiadiazolyl)]Amino-1-Methyl-4-Nitroimidazoles. Letters in Drug Design & Discovery, vol. 3, p. 98-101, 2006. 
• BOECHAT, N. ; COSTA, MS ; FERREIRA, V. ; WARDELL, S. ; SKAKLE, JMS . 4-Difluoromethyl-1-(2,5-dimethoxyphenyl)-1 H -1,2,3-triazole. ACTA CRYSTALLOGRAPHICA. SECTION E, Great Britain, v. 62, p. o2048–o2050, 2006. 
• BOECHAT, N. ; SKAKLE, J. M. S. ; COSTA, M. S. ; WARDELL, S. ; FERREIRA, V. . 4-Difluoromethyl-1-(4-methylphenyl)-1 H -1,2,3-triazole. ACTA CRYSTALLOGRAPHICA. SECTION E, Great Britain, v. 62, p. o1925-o1927, 2006. 
• BOECHAT, N. ; LAGES, AS ; SKAKLE, JMS ; WARDELL, S. ; KOVER, WB . 1-(4-Nitrobenzoyl)thiosemicarbazide monohydrate: a three-dimensional hydrogen-bonded framework structure. ACTA CRYSTALLOGRAPHICA. SECTION E, Great Britain, v. 62, p. o2563-o2565, 2006. 
• COSTA, MS ; BOECHAT, N .; RANGEL, EA ; SILVA, FC ; Souza, AMT (Alessandra MT Souza) ; RODRIGUES, CR ; CASTRO, HC ; NEVES JUNIOR, I .; LOURENCO, MCS ; WARDELL, S.; FERREIRA, V. . Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, v. 14, p. 8644-8653, 2006. 
• Doidge-Harrison ; BOECHAT, N .; FERREIRA, SB ; Glidewell, C.; Low, JN; SKAKLE, JMS; WARDELL, S. . 2-Amino-5-trifluoromethyl-1,3,4-thiadiazole and a redetermination of 2-amino-1,3,4-thiadiazole, both at 120-K: chains of edge-fused R 2 2 (8) and R 4 4 (10) rings, and sheets of R 2 2 (8) and R<. Acta Crystallographica Section C-Structural Chemistry, v. 62, p. o42-o44, 2006. 
• SOARES, RPP ; BOECHAT, N. ; KRETTLI, AU ; VASCONCELOS, TRA ; DE SOUZA, MVN . Evaluation of antimalarial and fluoroquinolone combinations against Plasmodium falciparum in vitro. International Journal of Antimicrobial Agents (Print), v. 28, p. 271-272, 2006. 
• BOECHAT, N .; MACIEL, LC ; PINTO, AC ; WARDELL, S.; SKAKLE, JMS; HOWIE, RA. 2-(2-Acetylamino-5-chlorophenyl)-2,2-difluoroethanoic acid and 2-(2-acetylamino-5-methylphenyl)-2,2-difluoroethanoic acid, and 2-(2-acetylaminophenyl)-2,2-difluoro- N -phenylacetamide and 2-(2-acetylaminophenyl)- N -(4-chlorophenyl)-2,2-difluoroacetamide: examples of variation in molecular packing and hydrogen-bonding motif induced by substituent change. Acta Crystallographica Section C-Structural Chemistry, v. 61, p. o270-o275, 2005. 
• BOECHAT, N. ; COSTA, J. ; MENDONCA, JS ; VINICIUS, M. ; VASCONCELOS, TRA ; OLIVEIRA, PSM . Simple Reduction of Heteroaromatic Esters to Alcohols Using a Sodium Borohydride-Methanol System. SYNTHETIC COMMUNICATIONS, v. 35, p. 3187-3190, 2005. 
• BOECHAT, N .; KDB Dutra; VALVERDE, AL ; WARDELL, S.; Low, JN; Glidewell, C. Hydrogen-bonded chains in 5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5- a ]pyrimidin-7(4 H )-one and hydrogen-bonded chains of rings in 5-amino-3-trifluoromethyl-1 H -1,2,4-triazole-5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5- a ]pyrimidin-7(4 H )-one (1/1), the co-crystal of a reaction produced. Acta Crystallographica Section C-Structural Chemistry, v. 60, p. o733-o736, 2004. 
• BOECHAT, N. ; COSTA, J. ; MENDONCA, JS ; OLIVEIRA, PSM ; SOUZA, MVN . A simple reduction of methyl aromatic esters to alcohols using sodium borohydride-methanol system. TETRAHEDRON LETTERS, v. 45, p. 6021-6022, 2004. 
• BOECHAT, N. ; COSTA, MS . Technological Development and Local Production of Antiretrovirals in Brazil. Proceedings of the 2003 II Forum on HIV/AIDS in Latin America and the Caribbean, Havana, 2003.
• BOECHAT, N. ; CARVALHO, AS ; FERREIRA, EF ; SOARES, ROA ; SOUZA, AS ; GIBALDI, D. ; BOZZA, M. ; PINTO, AC . Novel nitroimidazoles with trypanocidal and cell growth inhibition activities. Cytobios (Cessed in 2001), England, v. 105, p. 83-90, 2001. 
• BASTOS, MM ; JP Barbosa ; PINTO, AC ; KOVER, WB ; TAKEUCHI, Y.; BOECHAT, N. . Reductive debromination of 1-methyl-2,4,5-tribromoimidazole mediated by dry tetramethylammonium fluoride in aprotic solvents. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, v. 12, p. 417-421, 2001. 
• TORRES, JC ; GARDEN, S. ; PINTO, AC ; SILVA, FQ ; BOECHAT, N. . A synthesis of 3-fluoroindoles and 3,3-difluoroindolines by reduction of 3,3-difluoro-2-oxo-indoles using borane tetrahydrofuran complex. Tetrahedron (Oxford. Print), vol. 55, p. 1881-1892, 1999. 
• CLARK, JH ; WAILS, D.; JONES, C. W. ; SMITH, H.; BOECHAT, N .; MAYER, LMU ; MENDONCA, JS . Aromatic fluorodenitration using tetramethylammonium fluoride. J Chem Research, v. 1994, p. 2783-2794, 1994.
• BOECHAT, N .; CLARK, J.H. Fluorodenitration using tetramethylammonium fluoride. J. Chem. Soc. Chem. Commun., London, v. 1993, p. 921-922, 1993.
• BEAUMONT, A. ; CLARK, JH ; BOECHAT, N. . Selective fluorodenitration of chloronitroaromatics. J Fluorine Chem, oxford, v. 63, p. 25-30, 1993. 
• BOECHAT, N .; CLARK, J.H. A novel approach to the preparation of a pharmaceutical and agrochemical fluoroaromatic intermediate. Chem Ind, London, v. 1991, p. 436, 1991.

• BRANCO, FSC ; Boechat, Nubia . Medicinal Chemistry and Organic Synthesis of Drugs of Plant Origin. Knowledge, Sciences and Medicinal Plants: a multidisciplinary approach. 1st ed. Rio de Janeiro: Editora Fiocruz, 2024, v. 2024, p. 325-354.
• SOUZA JUNIOR, CAR; LEMES, EMB; Boechat, Nubia ; Magalhães JL . Big Data at the Service of the Public Health Systems: Success Cases in Brazilian Public Management. In: Magalhães, JL; Zulmira Hartz; George Leal Jamil; Henrique Silveira and Liliane C. Jamil,. (Org.). Handbook of Research on Essential Information Approaches to Aiding Global Health in the One Health Context. 1ed.Chicago: Hershey, PA: IGI Global, 2021, v. 2022, p. 204-218.
• Boechat, Nubia ; da Silva Pinheiro, Luiz Carlos ; da Silveira, Flavia Fernandes . Antiplasmodial Activity. In: Sülsen, Valeria Patricia; Martino, Virginia Susana. (Org.). Sesquiterpene Lactones. 1st ed. Berlin: Springer International Publishing, 2018, v. 2018, p. 197-221.
• Boechat, Nubia ; da Silva Pinheiro, Luiz . LEISHMANIASIS An Overview of New Synthetic Antileishmanial Candidates. In: Adilson Beatriz; Dennis Pires de Lima. (Org.). Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases. 1st ed.: BENTHAM SCIENCE PUBLISHERS, 2014, v. , p. 63-121.
• BOECHAT, N .; BASTOS, MM . An Update on Trifluoromethylation of Carbonyl Compounds. In: Atta-ur-Rahman. (Org.). Advances in Organic Synthesis. 5th edition.United States: Bentham Science Publishers, 2013, v. 5, p. 279-308.
• Boechat, Nubia ; Pinheiro, Luiz CS . Leprosy and its chemotherapy. In: Angelo C. Pinto; Vitor F. Ferreira. (Org.). Neglected Diseases. 1st ed. Rio de Janeiro: RVq, 2013, v. , p. 90-98.
• Bastos, Monica M. ; Boechat, Nubia ; Gomes, ATPC ; Neves, MGPM ; Cavaleiro, JAS . The use of porphyrins in photodynamic therapy in the treatment of Cutaneous Leishmaniasis. In: Angelo C. Pinto; Vitor F. Ferreira. (Org.). Neglected Diseases. 1st ed. Rio de Janeiro: RVq, 2013, v. , p. 108-119.
• Boechat, Nubia ; BRANCO, FSC ; Pinto, Angelo C. . MEDICINAL CHEMISTRY OF NEW MOLECULES FOR THE TREATMENT OF TUBERCULOSIS. In: Angelo C. Pinto; Vitor F. Ferreira. (Org.). Neglected Diseases. 1st ed. Rio de Janeiro: RVq, 2013, v. , p. 172-207.
• ANTUNES, A. ; Magalhães JL ; BOECHAT, N. . THE PHARMACEUTICAL INDUSTRY: Brazilian policies in the sector and the case of the public laboratory Farmanguinhos. Opportunities in Generic Medicines - The Brazilian pharmaceutical industry. Rio de Janeiro: INTERCIÊNCIA, 2008.

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