Dr. Andrea de Castro PEREZ (PhD)

Full time professor Federal University of Minas Gerais (UFMG), Brazil since 2002.

Professor of Pharmacology for the Courses of Medicine, Dentistry, Veterinary, Biology, Pharmacy.

PhD: UNICAMP, Brazil and King´s College (England).

POS-DOC University of Montreal (Canada), University of Leon (Spain), University Jean Monnet (France), University of Murcia (Spain).

Fluent in English, Portuguese, Spanish and French.

• Pharmacology
• Nociception
• Analgesia
• Inflammation
• Medicinal Plants

• GONÇALVES de QUEIROS, B. F FONSECA, C. F BARRA, A PEREZ, A. C Romero, T R L; DUARTE, I. D. G. Interaction between the Dopaminergic and Endocannabinoid systems promotes peripheral antinociception. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 987, p. 177, 2025.
• AGUIAR, DANIELLE DINIZ; PETROCCHI, JÚLIA ALVARENGA; DA SILVA, GRAZIELLE CAROLINE; LEMOS, VIRGÍNIA SOARES; CASTOR, MARINA GOMES MIRANDA E; PEREZ, ANDREA DE CASTRO; DUARTE, IGOR DIMITRI GAMA; ROMERO, THIAGO ROBERTO LIMA. Participation of the cannabinoid system and the NO/cGMP/KATP pathway in serotonin-induced peripheral antinociception. NEUROSCIENCE LETTERS, v. 818,p.137536, 2024.
• BARRA, WALACE; QUEIROZ, BÁRBARA; PEREZ, ANDREA; ROMERO, THIAGO; FERREIRA, RENATA; DUARTE, IGOR. Study on peripheral antinociception induced by hydrogen peroxide (H2O2): characterization and mechanisms. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, v. 1, p. s00210, 2024.
• AGUIAR, DANIELLE DINIZ; DA COSTA OLIVEIRA, CRISTINA; PETROCCHI, JÚLIA ALVARENGA; CASTOR, MARINA GOMES MIRANDA E; PEREZ, ANDREA CASTRO; DUARTE, IGOR DIMITRI GAMA; ROMERO, THIAGO ROBERTO LIMA. Collaborative action between noradrenergic and serotoninergic systems in peripheral antinociception in mice. Journal of Biosciences, v. 49, p. 66, 2024.
• AGUIAR, DANIELLE DINIZ; DA COSTA OLIVEIRA, CRISTINA; FONSECA, FLÁVIA CRISTINA SOUSA; DE ALMEIDA, DOUGLAS LAMOUNIER; CAMPOS PEREIRA, WILLIAM VALADARES; GUIMARÃES, FRANCISCO SILVEIRA; PEREZ, ANDREA CASTRO; DUARTE, IGOR DIMITRI GAMA; ROMERO, THIAGO ROBERTO LIMA. Peripherally injected canabidiol reduces neuropathic pain in mice: Role of the 5-HT1A and TRPV1 receptors. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,v.660,p.58-64,2023.
• MACHADO, D. P. D FONSECA, FLÁVIA CRISTINA SOUSA; PEREZ, ANDREA; DUARTE, IGOR D. Antinociceptive effects pf Psychotria veridis Ruiz & Pav. on carrageenan-induced hyperalgesia in rats. CURRENT TOPICS IN PHARMACOLOGY, v.27,p.1,2023.
• AGUIAR, DANIELLE DINIZ; CRISTINA, DA COSTA OLIVEIRA; PETROCCHI, JÚLIA ALVARENGA; PEREZ, ANDREA C DUARTE, IGOR; Romero, TRL. Interaction between the serotoninergic and noradrenergic systems during peripheral antinociception. CURRENT TOPICS IN PHARMACOLOGY, v. 27, p. 2, 2023.
• AGUIAR, DANIELLE DINIZ; GONZAGA, AMANDA CRISTINA REIS; TEÓFILO, ANA LUIZA HIGINO; MIRANDA, FERNANDA ALMEIDA; PEREZ, ANDREA DE CASTRO; DUARTE, IGOR DIMITRI GAMA; ROMERO, THIAGO ROBERTO LIMA. Curcumin induces peripheral antinociception by opioidergic and cannabinoidergic mechanism: Pharmacological evidence. LIFE SCIENCES, v. 293, p. 120279, 2022.
• SOARES, GUTEMBERG LOPES; HILGENBERG, LÍVIA CHRISTINE RIBEIRO; BATISTA, GIOVANA REIS; SOUZA, MATHEUS KLEBER DE JESUS; FERREIRA, RENATA CRISTINA MENDES; SILVA, IRISMARA SOUSA; MACHADO, TALLITA MARQUES; PINHEIRO, CARLOS CLEOMIR DE SOUZA; GUILHON-SIMPLICIO, FERNANDA; KLEIN, ANDRE; PEREZ, ANDREA DE CASTRO; LIMA, EMERSON SILVA; MOURA, CLARICE DE CARVALHO VELOSO. Caryocar villosum attenuates inflammation by inhibiting CXCL1 activation and peripheral hyperalgesia through opioid pathway modulation. ACTA AMAZONICA, v. 52, p. 245-253, 2022.
• CHARLIE-SILVA, IVES; FEITOSA, NATÁLIA M PONTES, LETICIA G FERNANDES, BIANCA H NÓBREGA, RAFAEL H GOMES, JULIANA M. M PRATA, MARIANA N. L FERRARIS, FAUSTO K MELO, DANIELA C CONDE, GABRIEL; RODRIGUES, LETÍCIA F ARACATI, MAYUMI F CORRÊA-JUNIOR, JOSÉ D MANRIQUE, WILSON G SUPERIO, JOSHUA; GARCEZ, AGUINALDO S CONCEIÇÃO, KATIA; YOSHIMURA, TANIA M NÚÑEZ, SILVIA C PEREZ, A. C et.al. Plasma proteome responses in zebrafish following λ-carrageenan-Induced inflammation are mediated by PMN leukocytes and correlate highly with their human counterparts. Frontiers in Immunology, v. 13, p. 01, 2022.
• MATOS, NATÁLIA ALVES DE; REIS, DIEGO CARLOS DOS; ROCHA, LUCAS KRAEMER; MATTOS, MATHEUS SILVÉRIO DE; CASSALI, GEOVANNI DANTAS; RUSSO, REMO CASTRO; PEREZ, ANDREA DE CASTRO; KLEIN, ANDRÉ. Pharmacological blockade of protease-Activated Receptor 2 improves airway remodeling and lung inflammation in experimental allergic asthma. BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES v. 58, p. 1, 2022.
• QUEIROZ, B.F.G FONSECA, F.C.S FERREIRA, R.C.M ROMERO, T.R.L PEREZ, A.C DUARTE, I.D.G. Analgesia and pain: Dual effect of dopamine on the peripheral nociceptive system is dependent on D2-or D1-like receptor activation. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 922, p. 174872, 2022.
• TEIXEIRA, L. R. M ANDREA, DE CASTRO PEREZ; ROMERO, THIAGO; DUARTE, I. D. G. Magnesium sulphate activates the L-arginine/NO/cGMP pathway to induce peripheral antinociception in mice. MAGNESIUM RESEARCH, v. 35, p. 1-10, 2022.
• SOARES-SANTOS, R. R MACHADO, D. P. D ROMERO, T. R. L PEREZ, A.C DUARTE, IGOR DIMITRI GAMA. Evaluation of local chromotherapy on carrageenanaininduced acute inflammatory pain in rats. current research in complementary and alternative medicine, v. 5, p. 1-7, 2021.
• GUZZO, LUCIANA; OLIVEIRA, C.C FERREIRA, R. C. M MACHADO, D. P. D; CASTOR, MARINA G.M PEREZ, A. C PISCITELLI, F DI MARZO, VINCENZO; ROMERO, T. R. L DUARTE, I. D. Kahweol, a natural diterpene from coffee, induces peripheral antinociception by endocannabinoid system activation. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, v. 54, p. e11071, 2021.
• GONÇALVES, WILLIAM A FERREIRA, RENATA C.M REZENDE, BARBARA M MAHECHA, GERMAN A.B GUALDRON, MELISSA; DE MACEDO, FLÁVIO H.P DUARTE, IGOR D.G PEREZ, ANDREA C MACHADO, FABIANA S CRUZ, JADER S ROMERO, THIAGO R.L. Endogenous opioid and cannabinoid systems modulate the muscle pain: A pharmacological study into the peripheral site. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 901, p. 174089, 2021.
• BELO, MARCO A.A OLIVEIRA, MELQUE F OLIVEIRA, SUSANA L ARACATI, MAYUMI F RODRIGUES, LETÍCIA F COSTA, CAMILA C CONDE, GABRIEL; GOMES, JULIANA M.M PRATA, MARIANA N.L BARRA, AYSLAN; VALVERDE, THALITA M DE MELO, DANIELA C ETO, SILAS F FERNANDES, DAYANNE C ROMERO, MARINA G.M.C CORRÊA JÚNIOR, JOSÉ D SILVA, JULIANA O BARROS, ANDRE L.B PEREZ, ANDREA C CHARLIE-SILVA, IVES; et.al. Zebrafish as a model to study inflammation: A tool for drug discovery. BIOMEDICINE & PHARMACOTHERAPY, v. 144, p. 112310, 2021.
• SOUZA, MATHEUS; SOARES, GUTEMBERG; GUILHON-SIMPLICIO, FERNANDA; PEREZ, ANDREA; MOURA, CLARICE. PHARMACOLOGICAL EVALUATION OF THE ANTINOCICEPTIVE AND ANTIINFLAMMATORY ACTIVITY OF THE SPECIES ENDOPLEURA UCHI. ENCICLOPÉDIA BIOSFERA, v. 18, p. 9, 2021.
• MOTTA, PATRÍCIA G GONZAGA, AMANDA C. R PEREZ, ANDREA C GUZZO, LUCIANA S ROMERO, THIAGO R. L DUARTE, IGOR D. G. Peripheral antinociceptive effect of exogenous acetylcholine seems to be mediated by M1 and nicotinic receptors. CURRENT TOPICS IN PHARMACOLOGY, v. 25, p. 77, 2021.
• CHARLIE-SILVA, I PEREZ, A. C DE MELO, N. F. S GOMES, J. M. M PORTELA, D SILVA, B FRACETO, L. F REZENDE-TEIXEIRA, P CORRÊA-JUNIOR, J. D CONCEIÇÃO, K PIEREZAN, F BELO, M. A. A LUZ, R. K. PHARMACOLOGICAL SCREENING OF MUCUS PRODUCED BY THE PACAMÃ FISH, Lophiosilurus alexandri. ARS VETERINÁRIA Jaboticabal, v. 37, p. 166-172, 2021.
• SILVA, I. C MAIA, C. A. A RAYMUNDO, A. C PRATA, M. N. L ROMERO, T. R. L DUARTE, I. D. G MANRIQUE, W. G PEREZ, A. C BELO, M. A. A. META-ANALYSIS OF THE THERAPEUTIC USE OF DIPYRONE IN DOGS: PHARMACOLOGICAL EFFECTS AND CLINICAL SAFETY. ARS VETERINÁRIA Jaboticabal, v. 37, p. 21, 2021.
• SUDERIO, L ANDREA, DE CASTRO PEREZ. Covid 19: yet a treatment to find. Annals of Clinical Pharm and Toxicol, v. 2, p. 1013, 2020.
• * PRATA, M.N.L CHARLIE-SILVA, I GOMES, J.M.M BARRA, A BERG, B.B PAIVA, I.R MELO, D.C KLEIN, A ROMERO, M.G.M. CASTOR; OLIVEIRA, C.C PIMENTA, L.P.S JÚNIOR, J.D.CORRÊA; PEREZ, A.C. Anti-inflammatory and immune properties of the peltatoside, isolated from the leaves of Annona crassiflora Mart., in a new experimental model zebrafish. FISH & SHELLFISH IMMUNOLOGY, v. 101, p. 234-243, 2020.
• OLIVEIRA, CRISTINA DA COSTA; CASTOR, MARINA GOMES MIRANDA E; CASTOR, CAMILA GOMES MIRANDA E; COSTA, ÁGHATA DE FRANÇA; FERREIRA, RENATA CRISTINA MENDES; SILVA, JOSIANE FERNANDES DA; PELAEZ, JULIANA MARIA NAVIA; CAPETTINI, LUCIANO DOS SANTOS AGGUM; LEMOS, VIRGINIA SOARES; DUARTE, IGOR DIMITRI GAMA; PEREZ, ANDREA DE CASTRO; SANTOS, SÉRGIO HENRIQUE SOUSA; ROMERO, THIAGO ROBERTO LIMA. Evidence for the involvement of opioid and cannabinoid systems in the peripheral antinociception mediated by resveratrol. TOXICOLOGY AND APPLIED PHARMACOLOGY, v. 369, p. 30-38, 2019.
• * DA COSTA OLIVEIRA, CRISTINA; DE MATOS, NATÁLIA ALVES; DE CARVALHO VELOSO, CLARICE; LAGE, GISELE AVELAR; PIMENTA, LÚCIA PINHEIRO SANTOS; DUARTE, IGOR DIMITRI GAMA; ROMERO, THIAGO ROBERTO LIMA; KLEIN, ANDRÉ; DE CASTRO PEREZ, ANDREA. Anti-inflammatory and antinociceptive properties of the hydroalcoholic fractions from the leaves of Annona crassiflora Mart. in mice. INFLAMMOPHARMACOLOGY, v. 001, p. on line, 2018.
• * VELOSO, C. C OLIVEIRA, M. C RODRIGUES, V. G OLIVEIRA, C. C DUARTE, L. P TEIXEIRA, M. M FERREIRA, A. V. M PEREZ, A. C. Evaluation of the effects of extracts of Maytenus imbricata (Celastraceae) on the treatment of inflammatory and metabolic dysfunction induced by high-refined carbohydrate diet. INFLAMMOPHARMACOLOGY, v. 001, p. on line, 2018.
• CICONINI, L CARRASCOZA, G. G PEREZ, A.C. Different effects of acetaminophen between male and female. United Journal of Phrmacology and Therapeutics, v. 1, p. 1, 2018.
• VELOSO, CLARICE C SOARES, GUTEMBERG L PEREZ, ANDREA C RODRIGUES, VANESSA G SILVA, FERNANDO C. Pharmacological potential of Maytenus species and isolated constituents, especially tingenone, for treatment of painful inflammatory diseases. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy, v. a, p. 1, 2017.
• PRATA, M. N. L CRISTINA, DA COSTA OLIVEIRA; CHARLIE-SILVA, Y Romero, T R L; PEREZ, ANDREA C. Anti-inflammatory effects of resveratrol. Journal of Medicinal Plants Studies, v. 5, p. 48, 2017.
• VELOSO, C. C FERREIRA, R. C. M RODRIGUES, V. G DUARTE, L. P KLEIN, A DUARTE, I. D ROMERO, T. R. L PEREZ, A. C. Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to cannabinoid receptors activation in mice. INFLAMMOPHARMACOLOGY, v. a, p. a, 2017.
• ALVES, JÚNIA C. O FERREIRA, GABRIELLA F SANTOS, JULLIANA R SILVA, LUÍS C. N RODRIGUES, JOÃO F. S NETO, WALLACE R. N FARAH, EMMANUELI I SANTOS, ÁQUILA R. C MENDES, BRENDA S SOUSA, LOURIMAR V. N. F MONTEIRO, ANDREA S DOS SANTOS, VERA L SANTOS, DANIEL A PEREZ, ANDREA C ROMERO, THIAGO R. L DENADAI, ÂNGELO M. L GUZZO, LUCIANA S. Eugenol Induces Phenotypic Alterations and Increases the Oxidative Burst in Cryptococcus. Frontiers in Microbiology, v. 8, p. 2419, 2017.
• ALMEIDA, R. T GALDINO, G. S PEREZ, A. C SILVA, G. C ROMERO, T. R. L DUARTE, I. D. G. ST36 ELECTROACUPUNCTURE ACTIVATES nNOS, iNOS AND ATP-SENSITIVE POTASSIUM CHANNELS TO PROMOTE OROFACIAL ANTINOCICEPTION IN RATS. JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, v. 68, p. 27-33, 2017.
• GUZZO, LUCIANA; CASTOR, MARINA; PEREZ, ANDREA; DUARTE, IGOR; ROMERO, THIAGO. Natural Diterpenes from Coffee, Cafestol, and Kahweol Induce Peripheral Antinoceception by Adrenergic System Interaction. Planta Medica, v. 82, p. 106-112, 2016.
• ALMEIDA, RENATO TEIXEIRA; ROMERO, THIAGO ROBERTO LIMA; ROMERO, MARINA GOMES MIRANDA E CASTOR; DE SOUZA, GIOVANE GALDINO; PEREZ, ANDREA DE CASTRO; DUARTE, IGOR DIMITRI GAMA. Endocannabinoid mechanism for orofacial antinociception induced by electroacupuncture in acupoint St36 in rats. Pharmacological Reports, v. 1, p. 1, 2016.
• * OLIVEIRA, CRISTINA; VELOSO, CLARICE; FERREIRA, RENATA; LAGE, GISELE; PIMENTA, LÚCIA; DUARTE, IGOR; ROMERO, THIAGO; PEREZ, ANDREA. Peltatoside Isolated from Annona crassiflora Induces Peripheral Antinociception by Activation of the Cannabinoid System. Planta Medica, v. 83, p. 261-267, 2016.
• * DE CARVALHO VELOSO, CLARICE; RODRIGUES, VANESSA GREGÓRIO; FERREIRA, RENATA CRISTINA MENDES; DUARTE, LUCIENIR PAINS; KLEIN, ANDRE; DUARTE, IGOR DIMITRI; ROMERO, THIAGO ROBERTO LIMA; DE CASTRO PEREZ, ANDREA. Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to NO/cGMP and ATP-sensitive K+ channels pathway activation in mice. European Journal of Pharmacology, v. 755, p. 1-5, 2015.
• * DE OLIVEIRA AZEVEDO, ADOLFO; CAMPOS, JUSSARA JÚLIA; DE SOUZA, GIOVANE GALDINO; DE CARVALHO VELOSO, CLARICE; DUARTE, IGOR DIMITRI GAMA; BRAGA, FERNÃO CASTRO; DE CASTRO PEREZ, ANDREA. Antinociceptive and anti-inflammatory effects of myricetin 3-O-β-galactoside isolated from Davilla elliptica: involvement of the nitrergic system. Natural Medicines, v. 1, p. on line, 2015.
• * GALDINO, G.S DUARTE, I. D. G PEREZ, A. C. Central release of nitric oxide mediates antinociception induced by aerobic exercise. Brazilian journal of medical and biological research, v. 00, p. 000-000, 2015.
• GUZZO, LUCIANA S ROMERO, THIAGO R.L QUEIROZ-JUNIOR, CELSO M CALIARI, MARCELO V AZEVEDO, ADOLFO O PEREZ, ANDRÉA C DUARTE, IGOR D.G. Involvement of endogenous opioid peptides in the peripheral antinociceptive effect induced by the coffee specific diterpene kahweol. Pharmacological Reports, v. 67, p. 1010-1015, 2015.
• DINIZ, DANIELLE A PETROCCHI, JÚLIA ALVARENGA; NAVARRO, LARISSA CALDEIRA; SOUZA, TÂMARA CRISTINA; CASTOR, MARINA G.M PEREZ, ANDREA C DUARTE, IGOR D.G ROMERO, THIAGO R.L. Serotonin induces peripheral mechanical antihyperalgesic effects in mice. European Journal of Pharmacology, v. 767, p. 94-97, 2015.
• CLARICE, DE CARVALHO VELOSO; VANESSA, GREGRIO RODRIGUES; ADOLFO, DE OLIVEIRA AZEVEDO; CRISTINA, DA COSTA OLIVEIRA; LINDISLEY, FERREIRA GOMIDES; LUCIENIR, PAINS DUARTE; IGOR, DIMITRI DUARTE; ANDRE, KLEIN; ANDREA, DE CASTRO PEREZ. Antinociceptive effects of Maytenus imbricata Mart. ex. Reissek (Celastraceae) root extract and its tingenone constituent. Journal of Medicinal Plant Research, v. 8, p. 68-76, 2014.
• * VELOSO, CLARICE DE CARVALHO; DE OLIVEIRA, MARINA CHAVES; OLIVEIRA, CRISTINA DA COSTA; RODRIGUES, VANESSA GREGÓRIO; GIUSTI-PAIVA, ALEXANDRE; TEIXEIRA, MAURO MARTINS; DUARTE, IGOR DIMITRI; FERREIRA, ADALIENE VERSIANI MATOS; PEREZ, ANDREA DE CASTRO. Hydroethanolic extract of Pyrostegia venusta (Ker Gawl.) Miers flowers improves inflammatory and metabolic dysfunction induced by high-refined carbohydrate diet. Journal of Ethnopharmacology, v. 151, p. 722-728, 2014.
• * GALDINO, GIOVANE; ROMERO, THIAGO R.L SILVA, JOSÉ FELIPE P AGUIAR, DANIELE C DE PAULA, ANA MARIA; CRUZ, JADER S PARRELLA, COSIMO; PISCITELLI, FABIANA; DUARTE, IGOR D DI MARZO, VINCENZO; PEREZ, ANDREA C. The endocannabinoid system mediates aerobic exercise-induced antinociception in rats. Neuropharmacology, v. 77, p. 313-324, 2014.
• * Galdino G; Romero, T R L; ANDRADE, I DUARTE, I. D. G PEREZ, A. C. Opioid receptors are not involved in the increase of the nociceptive threshold induced by aerobic exercise. Neurosciences, v. 19, p. 33-37, 2014
• COSTA, ALINE C.O ROMERO, THIAGO R.L PACHECO, DANIELA F PEREZ, ANDREA C SAVERNINI, ATILA; SANTOS, ROBSON R.A DUARTE, IGOR D.G. Participation of AT1 and Mas receptors in the modulation of inflammatory pain. Peptides (New York, N.Y. 1980), v. 61, p. 17-22, 2014.
• * VELOSO, CLARICE DE CARVALHO; ANDRE, KLEIN; DUARTE, IGOR D Romero, T R L; PEREZ, A. C. Tingenone, a Pentacyclic Triterpene, Induces Peripheral Antinociception Due to Opioidergic Activation. Planta Medica, p. 1615-1621, 2014.
• ADOLFO, DE OLIVEIRA AZEVEDO; DUARTE, I. D. G CASTRO, S. A Klein, A; PEREZ, ANDREA C. Antinociceptive and anti-inflammatory effects of the hydroalcoholic extract and cinnamic acid obtained from Lychnophora pinaster. journal of arts science and technology, v. 7, p. 35, 2014.
• * GALDINO, GIOVANE S XAVIER, CARLOS H ALMEIDA, RENATO; SILVA, GRAZIELLE; FONTES, MARCOS A MENEZES, GUSTAVO; DUARTE, IGOR D PEREZ., ANDREA C. The Nitric oxide/ C GMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats. INTERNATIONAL JOURNAL OF NEUROSCIENCE, v. 125, p. 765-773, 2014.
• CAMPOS, JUSSARA JÚLIA; DE OLIVEIRA AZEVEDO, ADOLFO; DE SOUZA FILHO, JOSÉ DIAS; CASTRO PEREZ, ANDREA; CASTRO BRAGA, FERNÃO. Bioguided isolation of myricetin-3-O-β-galactopyranoside with antinociceptive activity from the aerial part of Davilla elliptica St.-Hil. Journal of Ethnopharmacology, v. 150, p. 270-274, 2013.
• DA FONSECA PACHECO, DANIELA; DA FONSECA PACHECO, CINTHIA MARA; DE PAULA LIMA, MERCIA; BADER, MICHAEL; DE LIMA SOUZA, ALEXANDRO; LUIZ PESQUERO, JORGE; CASTRO PEREZ, ANDREA; DUARTE, IGOR DIMITRI GAMA. Antinociceptive response in transgenic mice expressing rat tonin. European Journal of Pharmacology, v. 713, p. 1-5, 2013.
• GALDINO, GIOVANE S DUARTE, IGOR D PEREZ, ANDREA C. Effect of dietary caloric restriction on the nociceptive threshold of rats that underwent aerobic and resistance exercise training. International Journal of Neuroscience, v. 124, p. 130822085204007, 2013.
• * DE SOUZA, GIOVANE GALDINO; DUARTE, IGOR DIMITRI; DE CASTRO PEREZ, ANDREA. Differential Involvement of Central and Peripheral α2 Adrenoreceptors in the Antinociception Induced by Aerobic and Resistance Exercise. ANESTHESIA AND ANALGESIA, v. 116, p. 703-711, 2013.
• Gomides, L.F DUARTE, I. D. G R.G. Ferreira; PEREZ, A. C Francischi J N; Klein, A. Proteinase-Activated Receptor-4 Plays a Major Role in the Recruitment of Neutrophils Induced by Trypsin or Carrageenan during Pleurisy in Mice. PHARMACOLOGY (ONLINE), v. 89, p. 275-282, 2012.
• PEREZ, A. C Romero, T R L; Guzzo LS Klein, A; DUARTE, I. D. G. Noradrenaline activates the NO/cGMP/ATP-sensitive K+ channels pathway to induce peripheral antinociception in rats. Nitric Oxide (Print), v. 26, p. 157-161, 2012.
• Guzzo LS PEREZ, A. C Romero, TRL; DUARTE, I. D. G. Cafestol a coffee specific diterpene induces peripheral antinociception mediated by endogenous opioid peptides. Clinical and Experimental Pharmacology & Physiology, v. 39, p. 412-416, 2012.
• PEREZ, A. C Romero, TRL; Galdino G; Resende LC; CORTES, S. F DUARTE, I. D. G. Involvement of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in peripheral antinociception induced by N-palmitoyl-ethanolamine in rats. Journal of Neuroscience Research, v. 90, p. 1474-1479, 2012.
• * DEFOUR, A DESSALLE, K PEREZ, A. C POYOT, T CASTELLS, J FREYSSENET, D. Sirtuin 1 Regulates SREBP-1c Expression in a LXR-Dependent Manner in Skeletal Muscle. PLoS One, v. 7, p. e43490, 2012.
• Reis, GML; Ramos, M.A PEREZ, A. C Klein, A; DUARTE, I. D. G. Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. LIFE SCIENCES, v. 88, p. 653-657, 2011.
• Romero, T R L; Galdino G; CORTES, S. F PEREZ, A. C DUARTE, I. D. G. Ketamine Activates the l-Arginine/Nitric Oxide/Cyclic Guanosine Monophosphate Pathway to Induce Peripheral Antinociception in Rats. ANESTHESIA AND ANALGESIA, v. 113, p. 1254-1259, 2011.
• MOTTA, P. G PEREZ, A. C ALVES, D. P DUARTE, I. D. G. Peripheral Control of Inflammatory but Not Neuropathic Pain by Endogenous Cholinergic System. PHARMACOLOGY (ONLINE), v. 88, p. 18-25, 2011.
• PEREZ, A. C MOTTA, P. G ALVES, D. P DUARTE, I. D. G. Modulation of Peripheral Inflammatory Pain Thresholds by M1 and Nicotinic Receptor Antagonists. Pharmacology (Online), v. 88, p. 309-315, 2011.
• * Galdino G; DUARTE, I. D. G PEREZ, A. C. Evaluation of exercise and potassium chloride supplementation on blood pressure and nociceptive threshold in hypertensive rats. Applied Physiology Nutrition and Metabolism, v. 35, p. 184-187, 2010.
• Galdino G; CORTES, S. F DUARTE, I. D. G PEREZ, A. C. Involvement of the nitric oxide/CGMP/KATP pathway in antinociception induced by exercise in rats. LIFE SCIENCES, v. 86, p. 505-509, 2010.
• Galdino G; DUARTE, I. D. G PEREZ, A. C. Participation of endogenous opioids in the antinociception induced by resistance exercise in rats. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, v. 43, p. 906-909, 2010.
• Romero, TRL; PEREZ, A. C Francischi J N; DUARTE, I. D. G. Probable involvement of α2C-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 608, p. 23-27, 2009.
• Reis, GML; Pacheco D; PEREZ, A. C Klein, A; Ramos, M.A DUARTE, I. D. G. Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. LIFE SCIENCES, v. 85, p. 351-356, 2009.
• PACHECO, D. F KLEIN, A PEREZ, A. C PACHECO, C. M. F FRANCISCHI, J. N REIS, G.M.L DUARTE, I. D. G. Central antinociception induced by μ-opioid receptor agonist morphine, but not δ- or κ-, is mediated by cannabinoid CB1receptor. BRITISH JOURNAL OF PHARMACOLOGY, v. 158, p. 225-231, 2009.
• Pacheco D; PEREZ, A. C Francischi J N; DUARTE, I. D. G. The μ-opioid receptor agonist morphine, but not agonists at δ- or κ-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors. BRITISH JOURNAL OF PHARMACOLOGY, v. 154, p. 1143-1149, 2008.
• Almeida RT; PEREZ, A. C Francischi J N; CASTRO, S. A DUARTE, I. D. G. Opioidergic orofacial antinociception induced by electroacupuncture at acupoint St36. Brazilian Journal of Medical and Biological Research (on line), v. 41, p. 621-626, 2008.
• Reis, GML; Pacheco D; Francischi J N; CASTRO, S. A PEREZ, A. C DUARTE, I. D. G. Involvement of GABAA receptor-associated chloride channels in the peripheral antinociceptive effect induced by GABAA receptor agonist muscimol. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 564, p. 112-115, 2007.
• * Azevedo, A.O Braga, F.C DUARTE, I. D. G PEREZ, A. C. Antinociceptive effect from Davilla elliptica hydroalcoholic extract. JOURNAL OF ETHNOPHARMACOLOGY, v. 113, p. 354-356, 2007.
• * PEREZ, A. C. Effect of Solanum lycocarpum St. Hill on various haematological parameters in diabetic rats. JOURNAL OF ETHNOPHARMACOLOGY, v. 106, p. 442-444, 2006.
• Rodrigues, A R A; CASTRO, S. A Francischi J N; PEREZ, A. C DUARTE, I. D. G. Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, v. 38, p. 1, 2005.
• Cabral de Oliveira C PEREZ, A. C Prieto J G; DUARTE, I. D. G Alvarez A I. Protection of Panax ginseng in injured muscles after eccentric exercise. JOURNAL OF ETHNOPHARMACOLOGY, v. 97, p. 211-214, 2005.
• Pacheco D; Reis, GML; Francischi J N; CASTRO, S. A PEREZ, A. C DUARTE, I. D. G. δ-Opioid receptor agonist SNC80 elicits peripheral antinociception via δ1 and δ2 receptors and activation of the l-arginine/nitric oxide/cyclic GMP pathway. LIFE SCIENCES, v. 78, p. 54-60, 2005.
• D P Alves; A C Soares; Francischi J N; CASTRO, S. A PEREZ, A. C DUARTE, I. D. G. Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 489, n.1, p. 59-65, 2004.
• Alvarez A I; Cabral de Oliveira C PEREZ, A. C Vila L; Prieto J G. The Effect of Ginseng on Muscle Injury and Inflammation. Journal of Ginseng Research, v. 28, n.1, p. 18-26, 2004.
• Voces J; Cabral de Oliveira C Prieto J G; Vila L; PEREZ, A. C DUARTE, I. D. G Alvarez A I. Ginseng administration protects skeletal muscle from oxidative stress induced by acute exercise in rats. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, brasil, v. 37, p. 1863-1871, 2004.
• * PEREZ, ANDREA C; CABRAL DE OLIVEIRA, ANTONIO C; ESTEVEZ, EMMA; MOLINA, ANTONIO J; PRIETO, JULIO G; ALVAREZ, ANA I. Mitochondrial, sarcoplasmic membrane integrity and protein degradation in heart and skeletal muscle in exercised rats. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, v. 134, p. 199-206, 2003.
• Cabral de Oliveira C PEREZ, A. C. dolor muscular tardio:un analisis de los procesos autogenico, fagocitico y regenerativo de la lesion. Archivos de Medicina Del Deporte, espanha, v. 19, n.87, p. 55-62, 2002.
• * PEREZ, A. C Cabral de Oliveira C Prieto J G; Ferrando A; Vila L; Alvarez A I. Quantitative assessment of nitric oxide in rat skeletal muscle and plasma after exercise. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, alemanha, v. 88, p. 189-191, 2002.
• PEREZ, A. C Cabral de Oliveira C. efectos del oxido nitrico en la fisiologia muscular. Efdeportes, argentina, v. 39, 2001.
• Cabral de Oliveira C PEREZ, A. C. Dolor muscular tardio: un analisis del proceso inicial de la lesion. Archivos de Medicina Del Deporte, Espanha, v. 18, n.84, p. 297-303, 2001.
• CABRAL DE OLIVEIRA, ANTONIO C; PEREZ, ANDREA C; MERINO, GRACIA; PRIETO, JULIO G; ALVAREZ, ANA I. Protective effects of Panax ginseng on muscle injury and inflammation after eccentric exercise. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, v. 130, p. 369-377, 2001.
• PEREZ, A. C. Efeito anti-inflamatório da folha de Ipomoea batatas. Revista de Odontologia da UNESP, Brasil, 1999.
• PEREZ, A. C. radicais livres em periodontia. Journal of Biomolecular Medicine & Free Radicals, Brasil, v. 5, n.2, p. 38-40, 1999.
• PEREZ, A. C. Anti-ulcer activity from the leaves of Bryophyllum sp. Archives of Veterinary Science, Brasil, v. 4, n.1, p. 111-112, 1999.
• PEREZ, A. C. Efeito do oxido nítrico na reparação óssea. Revista Biociencias, Brasil, v. 4, n.1-2, 1998.
• PEREZ, A. C. The effect of L-arginine on guinea-pig and rabbit airway smooth muscle function in vitro. Brazilian Journal of Medical and Biological Research, brasil, v. 31, p. 811-818, 1998.
• PEREZ, A. C. Efeito da inibição crônica do oxido nítrico no rim de ratos diabeticos. Revista de Odontologia da UNESP, Brasil, v. 26, n.2, p. 297-305, 1997.
• PEREZ, A. C. Oxido nítrico e odontologia. Journal of Biomolecular Medicine & Free Radicals, Brasil, v. 3, n.4, p. 119-121, 1997.
• PEREZ, A. C. Oxido nítrico, um radical livre na pesquisa. Journal of Biomolecular Medicine & Free Radicals, Brasil, v. 3, n.3, p. 103-104, 1997.
• * PEREZ, A. C. Persistence of effects of nitric oxide synthase inhibitors: Comparisons on blood flow and plasma exudation in guinea pig skin. EUROPEAN JOURNAL OF PHARMACOLOGY, Inglaterra, v. 330, p. 241-246, 1997.
• PEREZ, A. C. Plasma protein exudation and blood flow changes in cutaneous inglammation: some discrepant observations. Inflammation Research, inglaterra, v. 44, p. s223, 1995.
• PEREZ, A. C. Inhibition of serum-induced proliferation of bovine tracheal smooth muscle cells in culture by heparin and related glycosaminoglycans. BRITISH JOURNAL OF PHARMACOLOGY, Inglaterra, v. 114, p. 1442-1446, 1995.
• PEREZ, A. C. Crotoxin induces aggregation of human washed platelets. TOXICON, inglaterra, v. 32, n.2, p. 217-226, 1994.
• PEREZ, A. C. Cutaneous permeability responses to bradykinin and histamine in the guinea-pig: possible differences in their mechanism of action. BRITISH JOURNAL OF PHARMACOLOGY, Inglaterra, v. 111, p. 159-164, 1994.
• PEREZ, A. C. inhibition of airway smooth muscle proliferation by heparin, low molecular weight heparin and heparan sulphate. Eur. Respir. J., Inglaterra, v. 6, n.17, p. S273, 1993.
• PEREZ, A. C. The inhibition of thrombin-induced human platelet aggregation by proteins present in serum from the opossum didelphis albiventris. Thromb Haemorrh Disorders, USA, v. 6, p. 41-46, 1992.

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