Editor Profile
Hammed O. Faleke
Doctoral Researcher
Present
Texas Tech University
Lubbock
United States
Hammed O. Faleke
Department of Chemistry and Biochemistry, Texas Tech University, 3002, 4th Street Apt C075, Lubbock, TX 79415.
Phone: +1-806-241-3423
Email: hfaleke@ttu.edu
Education
- Texas Tech University, Lubbock, TX, January 2023 – Present, Ph.D. in Chemistry, Advisor: Dr. Dimitri Pappas, Research Focus: Functionalized carbon dots for disease diagnostics.
- University of Ibadan, Nigeria, March 2018 – February 2021, Master of Science in Biochemistry, GPA: 4.40/7.0, Thesis: Methanol fraction of Ficus mucoso prevents iron-induced oxidative damage in Drosophila melanogaster.
- Osun State University, Nigeria, September 2012 – December 2016, Bachelor of Science in Biochemistry (Honors) GPA: 4.37/5.0, Thesis: Peptides of Thaumatococcus daniellii seeds: Effects on cytochrome c oxidase and catalase activities.
Research Experience
Graduate Research Assistant, Texas Tech University, Lubbock, TX Jan 2023 – Present, Department of Chemistry and Biochemistry.
1. Developing functionalized carbon dots for detecting oxidative stress in neurodegenerative diseases.
2. Using Drosophila melanogaster as an in vivo nanoparticle localization and toxicity study model.
3. Exploring early detection strategies for Cancer and Neurodegenerative diseases.
Research Assistant, ADINA Research and Training Center, Ibadan, Nigeria May 2021 – Dec 2022
1. Developed and optimized different plant extraction techniques.
2. Utilized cutting-edge machinery and technology to extract and purify plants to their maximum potential.
3. Separated and refined bioactive substances from medicinal plants.
Research Assistant, University of Ibadan, Nigeria March 2018 – Dec 2022, Department of Biochemistry
1. Conducted research on metal toxicants and their mitigation using natural products in Drosophila melanogaster.
2. Extracted and purified bioactive compounds from medicinal plants.
3. Analyzed mitochondrial dysfunction and oxidative stress using spectrophotometry.
- Chemistry
- Biochemistry
- Biotechnology
- Nanomedicine
- Life Sciences
- Oxidative Stress
- Neurodegenerative Diseases
- Molecular Toxicology
- Pharmaceutical Microbiology
- Animal Models
- Biochemical Assays
- Molecular Techniques
- H Faleke, D Pappas. 2025 In vitro detection of iron overload in leukemia cells using ophenylenediamine-derived carbon dots. Next Materials.
- H Faleke, D Pappas. 2025 Histidine-Derived Carbon Dots as Luminescent Probes for Detecting Apoptosis Analytical and Bioanalytical Chemistry.
- FB Musa, TA Oyedeji, AO Olowofolahan, HO Faleke, OO Olorunsogo. 2025 Induction of mitochondrial-dependent apoptosis, activation of mitochondrial ATPase and cytochromec release by the methanol extract of Funtumia elastica stem bark. Journal of Complementary and Integrative Medicine
- H Faleke, V Sawant, G Christopher, D Pappas. 2024 Combatting Antibiotic-Resistant Pathogens: Disrupting Pseudomonas Aeruginosa Biofilm Viscoelasticity Using Carbon Dot Nanoparticles Electrochemical Society Meeting Abstracts 245.
- OT Oyebode, IJ Bello, H Faleke, J Danisa, OO Olorunsogo. 2023 Protective effect of vitamin E against plumbagin-induced liver injury. Comp Clin Pathol.
- Attah, A.F., Ayanniyi, R.O., Ojuade, F.I., Opara, F.C., Faleke, H., Adedoyin, K.J. and Adeyeye, S.O., 2023. Anti-inflammatory, Analgesic and GCMS Analysis of Ethanol Extract of a Polyherbal Phytomedicine Used in Nigerian Ethnomedicine. Tropical Journal of Natural Product Research, 7(10).
- Fasae, K.D., Adeyemi, O., Faleke, H.O. and Abolaji, A.O., 2023. Neurotoxicity of iron (Fe) in Drosophila and the protective roles of natural products. In Advances in Neurotoxicology (Vol. 9, pp. 321-342). Academic Press.
- Owumi, S.E., Irozuru, C.E., Arunsi, U.O., Faleke, H.O. and Oyelere, A.K., 2022. Caffeic acid mitigates aflatoxin B1-mediated toxicity in the male rat reproductive system by modulating inflammatory and apoptotic responses, testicular function, and the redox-regulatory systems. Journal of food biochemistry, 46(5), p.e14090.
- Oyebode OT, Abolaji AO, Faleke HO, Olorunsogo OO, Methanol fraction of Ficus mucoso (welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction in Drosophila melanogaster Drug Chem Toxicol. 2021.
- Faleke HO, Alimi-Adeniran OO, Oroye AR, Awope OR, Sowale OO, Molehin OR, Attah AF, Ajayi EIO. Hormetic modulation of wound healing, catalase and cytochrome oxidase activities by cationic peptides of some African plant seeds. (2017). In: Translating Research Findings into Policy in Developing Countries: Health, Infection and Treatment - Contributions from Humboldt Kolleg Osogbo-2017, Ed Olusola Ojurongbe. Germany: Lambert Academic Publishing; 2017. pp. 145-156.
