Name: Prof.Dr. Eman Ali Abd El-Meguid Mabrouk.

Current Job: Professor of Pharmaceutical Chemistry.

Department: Chemistry of Natural and Microbial Products.

Division: Pharmaceutical & Drug Industries Research Division.

E-mail: emannrc@yahoo.com & ea.mabrouk@nrc.sci.eg

Address: Villa 224, one Street 1st district, 7th region, Fifth Settlement.

Birth date: 6/2/1982.

Academic Qualifications:

• Ph. D. in Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, [2012].
• M. Sc. in Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, [2008].
• B. Sc. in Pharmacy and Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, [2004] with general grade Excellent with honors.

Professional Experience:

1. Professor of Pharmaceutical Chemistry at Chemistry of Natural and Microbial Products Dept.,
   National Research Center, from [2022].
2. Associate professor of Pharmaceutical Chemistry at Chemistry of Natural and Microbial
   Products Dept., National Research Center, from [2017].
3. Researcher of Pharmaceutical Chemistry at Chemistry of Natural and Microbial Products
   Dept., National Research Center, from [2012].
4. Research Assistant of Pharmaceutical Chemistry at Chemistry of Natural and Microbial
   Products Dept., National Research Center, from [2009-2012].
5. Demonstrator of Pharmaceutical Chemistry Faculty of Pharmacy, 6th October University,
   [2004 - 2006].

• Pharmaceutical Chemistry
• Organic Chemistry

• Eman A. Abd El-Meguid, Eman M. Mohi El-Deen, Gaber O. Moustafa, Hanem M. Awad, Eman S. Nossier. Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1. Bioorg. Chem. Under Press online 19 November (2021). https://doi.org/10.1016/j.bioorg.2021.105504
• Eman A. Abd El-Meguid, Gaber O. Moustafa, Hanem M. Awad, Eman R. Zaki, Eman S. Nossier. Novel benzothiazole hybrids targeting EGFR: Design, synthesis, biological evaluation and molecular docking studies. J. Mol. Struc., 1240, 130595, (2021) https://doi.org/10.1016/j.molstruc.2021.130595
• Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Eman A. Karam, Eman S. Nossier and Marwa F. Ahmed. Synthesis and biological evaluation of new pyridothienopyrimidine derivatives as antibacterial agents and Escherichia coli Topoisomerase II inhibitors. Antibiotics 9, 695; (2020) doi:10.3390/antibiotics9100695
• Eman A. Abd El-Meguid, Eman M. Mohi El-Deen, Manal A. Nael, Manal M. Anwar. Novel benzimidazole derivatives as anti-cervical cancer agents of potential multi-targeting kinase inhibitory activity. Arab. J. Chem. 13, 9179–9195, (2020) https://doi.org/10.1016/j.arabjc.2020.10.041
• H. T. Abdel‐Mohsen, Eman A. Abd El‐Meguid, Ahmed M. El Kerdawy, Abeer E. E. Mahmoud, Mamdouh M. Ali. Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer. Arch. Pharm. e1900340 (2020).https://doi.org/10.1002/ardp.201900340.
• Iman A.Y. Ghannam, Eman A. Abd El-Meguid, Islam H. Ali, Donia H. Sheir, Ahmed M. El Kerdawy. Novel 2-arylbenzothiazole DNA gyrase inhibitors: Synthesis, antimicrobial evaluation, QSAR and molecular docking studies. Bioorg. Chem. 93 103373 (2019). https://doi.org/10.1016/j.bioorg.2019.103373
• Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Sherifa Hasabelnaby, Eman A. Karam and Eman S. Nossier. Synthesis, docking studies, and in vitro evaluation of some novel thienopyridines and fused thienopyridine–quinolines as antibacterial agents and DNA gyrase inhibitors. Molecules, 24, 3650; (2019) doi:10.3390/molecules24203650.
• Eman A. Abd El-Meguid, H.M. Awad, M.M. Anwar. Synthesis of New 1,3,4-Oxadiazolebenzimidazole Derivatives as Potential Antioxidants and Breast Cancer Inhibitors with Apoptosis Inducing Activity. Russ. J. Gen. Chem, 89; 348–356 (2019).
• Salwa F. Mohamed, Eman R. Kotb, Eman A. Abd El-Meguid, and Hanem M. Awad. Synthesis and anticancer activity of novel 2-substituted pyranopyridine derivatives. Res.Chem. Intermed., 43(1), pp437-456, (2017).
• Eman A. Abd El-Meguid and Mamdouh M Ali. Synthesis of some novel 4-benzothiazol-2-yl-benzoyl-1H-pyrazoles, and evaluation as antiangiogenic agents. Res. Chem. Intermed., 42(2), pp1521-1536, (2016).
• Kamilia M. Amin, Eman A. Abd El-Meguid, Samy A. El-Assaly and Wageeh S. El-Hamouly. Synthesis, antibreast cancer activity and docking study of some novel 4-(benzo[d]thiazol-2-yl)phenyl moiety as CDK2 inhibitors. Int. J. Pharm. Technol., 8(1), pp10853-10871, (2016).
• Eman A. Abd El-Meguid and Mamdouh M Ali. Anticancer Evaluation of Some Newly Synthesized Oxadiazol-2-yl-Pyrazole Derivatives Attached To 4-Benzothiazol-2-yl Moiety. Res. J. Pharm. Biol. Chem. Sci. 6(2), pp524-532, (2015).
• Eman A. Abd El-Meguid, Eman R. Kotb and Salwa F. Mohamed. Synthesis and antibreast cancer evaluation of some novel schiff's bases and their c-nucleoside derivatives incorporating a 4-benzothiazol-2-yl moiety. Int. J. Pharm. Technol., 7(1), pp8363-8382, (2015).
• Eman A. Abd El-Meguid. Synthesis and antimicrobial evaluation of some novel sulfamoyl and triazole derivatives incorporating a 4-benzoimidazol-2-moiety. Int. J. Pharm. Technol., 7(3), pp10014-10028, (2015).
• Eman A. Abd El-Meguid. Discovery of some novel benzothiazole derivatives as VEGFR-2 inhibitors. Int. J. Pharm. Technol., 7(3), pp10040-10055, (2015).
• Eman A. Abd El-Meguid. Synthesis and antimicrobial activity of some amino acids and sulfamoyl and pyrrole derivatives attached to 4-benzoimidazol-2-yl moiety. Egypt. Pharmaceut. J. 13(2), pp113-120, (2014).
• Eman A. Abd El-Meguid, Nayera A.M. Abdelwahed. Synthesis and antimicrobial evaluation of some novel benzoimidazole Schiff’s bases and their C-nucleoside derivatives. Egypt. Pharmaceut. J., 13(2), pp130-136, (2014).
• Eman A. Abd El-Meguid and Mamdouh M Ali. Synthesis and Biological Evaluation of Some New Substituted-Pyrazole Attached to 4-(Benzothiazol-2-yl) Moiety as Antiangiogenic Agents. Res. J. Pharm. Biol. Chem. Sci., 5(6), pp888-897, (2014).
• Wageeh S. El-Hamouly, Kamilia M. Amin, Samy A. El-Assaly and Eman A. Abd El-Meguid. Synthesis and antitumor activity of some new N-substituted-sulfonyl, 1,2,4-triazole, N-substituted-benzylidene and pyrrole derivatives attached to 4-(benzo[d]thiazol-2-yl)benzohydrazide. Der Pharma Chemica, 3(6), pp293-306, (2011).
• Wageeh S. El-Hamouly, Kamilia M. Amin, Samy A. El-Assaly and Eman A. Abd El- Meguid. Synthesis and antitumor activity of some new 1,3,4-oxadiazole, pyrazole and pyrazolo[3,4-d]pyrimidine derivatives attached to 4-benzothiazol-2-yl phenyl moiety. Der Pharma Chemica, 3(6), pp282-292, (2011).
• Wageeh S. El-Hamouly, Kamilia M. Amin, Eman M. H. Abbas and Eman A. Abd El- Meguid. Synthesis and Antimicrobial Activity of Some 3-Substituted- 5,6-dimethoxy 2,3- dihydrobenzo[d]thiazol-2-one. Chin. J. Chem., 27, pp1629-1634, (2009).
• Wageeh S. El-Hamouly, Kamilia M. Amin, Eman M. H. Abbas and Eman A. Abd El-Meguid. Synthesis and Antimicrobial Activity of Some Substituted 1,3,4-Oxadiazole and Other Heterocycles Derived From 4,5-dimethoxy-2-Nitrophenyl-Thioacetic Hydrazide. Egypt. Pharmaceut. J., 1, pp127- 136, (2008).

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