Ghada M. El-Sayed is a researcher specializing in microbial genetics, biological control, metagenomics, microbiome studies, and microbial bioinformatics. Her research focuses on understanding microbial diversity and functional dynamics in ecological and host-associated systems, with applications in sustainable agriculture and pest management. She is particularly interested in the use of beneficial microorganisms and entomopathogenic agents as environmentally friendly alternatives to chemical control strategies. Her work integrates molecular genetics, high-throughput sequencing approaches, and computational bioinformatics tools to analyze microbial communities and their functional roles. Through interdisciplinary approaches, she aims to contribute to advancing biological control strategies and microbiome-based solutions for improving ecosystem health and agricultural productivity.

• Microbial genetics and functional genomics
• Biological control of agricultural pests and pathogens
• Metagenomics and microbial community profiling
• Microbiome structure, function, and host–microbe interactions
• Microbial bioinformatics and computational data analysis
• Entomopathogenic microorganisms and their applications in pest management
• Sustainable and eco-friendly agricultural biotechnologies
• Molecular mechanisms of microbial–insect interactions
• High-throughput sequencing and multi-omics approaches in environmental microbiology

• Ghada M. El-sayed, Nivien A. Abosereih, S. A. Ibrahim, A. B. Abd ElRazik, M.A. Hammad and F. M. Hafez Identification of gene encoding organophosphorus hydrolase (OPH) enzyme in potent organophosphates-degrading bacterial isolates. Journal of Environmental Science and Technology, 2018, 11(4), pp. 175–189
• Wafaa M.A. El-Nagdi, Hassan Abd-El-Khair, Gaziea M. Soliman, Hoda H. Ameen and Ghada M. El-Sayed. Application of protoplast fusants of Bacillus licheniformis and Pseudomonas aeruginosa on Meloidogyne incognita in tomato and eggplant. Middle East Journal of Applied Science. Volume : 09 | 2019 Pages: 622- 629
• Ghada M. El-sayed, Nivien A. Abosereih1, S. A. Ibrahim, A. B. Abd El-Razik, M.A. Hammad and F. M. Hafez Enhancement of Diazinon Degradation, Isolation of Organophosphorus Hydrolase and Chemical Analysis of Metabolites (2019) Egypt. J. Chem. Vol. 62, No. 11, pp. 2131 - 2142
• Ghada M. El-sayed, Nivien A. Abosereih, S. A. Ibrahim, A. B. Abd El-Razik, M.A. Hammad and F. M. Hafez Cloning of the organophosphorus hydrolase (oph) gene and enhancement of chlorpyrifos degradation in the Achromobacter xylosoxidans strain GH9OP via mutation induction. Jordan Journal of Biological Sciences, 2019, 12(3), pp. 307–315
• El-Sayed, N.S., Awad, H., El-Sayed, G.M. Synthesis and characterization of biocompatible hydrogel based on hydroxyethyl cellulose-g-poly(hydroxyethyl methacrylate). Polym. Bull. 77, 6333–6347 (2020). https://doi.org/10.1007/s00289- 019-02962-1
• Ghada M. El-Sayed, Rasha G. Salim, Soher E-S. Aly and Nivien A. Abosereh Molecular Characterization and Expression Analysis of aflR, aflS, and aflD in Non-Aflatoxigenic and Aflatoxigenic Aspergillus flavus Treated with Gallic Acid. Jordan Journal of Biological Sciences. 2021, 4: 709 – 717.
• Shereen A.H. Mohamed, Ghada M. El-Sayed , Usama S. Elkelany, Mahmoud M.A. Youssef, Wafaa M.A. El-Nagdi, Gaziea M. Soliman. local Bacillus spp.: isolation, genetic improvement, nematode biocontrol, and nitrogen fixation. Egyptian Pharmaceutical Journal 2021, 20:352–363
• Osama Ibrahim, Pawel Glibowski, Rasha G. Salim, Ghada M. El-Sayed. Transglutaminase from UV Mutated Bacillus cereus NRC215: Production, Purification, and Characterization. 2022, 5: 5753 – 5771.
• Abosereh, NA; Salim, RG; El-Sayed, AF; Hammad, M; El-Sayed, Ghada M. In-vitro biodegradation of Glyphosate using genetically improved bacterial isolates from highly polluted wastewater. 2022. Egyptian Journal of Chemistry. 65. 669-681
• Rasha G. Salim, Mohamed Fadel, Yehya A. Youssef, Hanan A. A. Taie, Nivien A. Abosereh, Ghada M. El Sayed and Mohamed Marzouk. A local Talaromyces atroroseus TRP-NRC isolate: isolation, genetic improvement, and biotechnological approach combined with LC/HRESI-MS characterization, skin safety, and wool fabric dyeing ability of the produced red pigment mixture. Journal of Genetic Engineering and Biotechnology. 2022, 20, 62:1-22.
• Osman, H.A., Ameen, H.H., Hammam, MMA; , Dawood MG; ; El-Sayed, GM; Elkelany, US; Abd Elgawad, MMM. Antagonistic potential of an Egyptian entomopathogenic nematode, compost, and two native endophytic bacteria isolates against the root-knot nematode (Meloidogyne incognita) infecting potato under field conditions. 2022. Egypt J Biol Pest Control. 32:137. https://doi.org/10.1186/s41938-022-00635-2
• Shaimaa A. Nour, Ghada M. El Sayed, Hanan A. A. Taie, Maha T. H. Emam, Ahmed F. El Sayed and Rasha G. Salim. Safe production of Aspergillus terreus xylanase from Ricinus communis: gene identification, molecular docking, characterization, production of xylooligosaccharides, and its biological activities. Journal of Genetic Engineering and Biotechnology. 2022, 20,121:1-26
• Ghada M. El-Sayed, Maha T. H. Emam, Maher A. Hammad, and Shaymaa H. Mahmoud. Gene Cloning, Heterologous Expression, and In Silico Analysis of Chitinase B from Serratia marcescens for Biocontrol of Spodoptera frugiperda Larvae Infesting Maize Crops. Molecules. 2024, 29, 1466:1-25
• Ahmed F. Roumia, Walaa Hussein, Ghada M. El-Sayed, Amr M.A. Elmasry and Sameh F. Fahim. In-Silco and In-Vitro Characterization of a Symbiotic Association Bacteria Isolated from Entomopathogenic Nematodes and Producers for Biological Control Non-Ribosomal Peptides. Egyptian Academic Journal of Biological Sciences F. Toxicology & Pest Contro. 2022, 14:117-131.
• Soliman, GM; El-Sawy, SM; Salim, RG; El-Sayed GM; Ramadan WA. Bioefficacy of Bacillus cereus and its Three Mutants by UV Irradiation Against Meloidogyne Incognita and Gene Expression in Infected Tomato Plants 2023. Jordan Journal of Biological Sciences. 16, 233-242.
• G.M. EL-SAYED, G.M. SOLIMAN, U.S. ELKELANY, H.H. AMEEN , S.A. NOUR, and W. HUSSEIN. Overproduction of neutral protease in Bacillus subtilis 168 through site-directed mutation for biocontrol of meloidogyne incognita. SABRAO Journal of Breeding and Genetics. Accepted on 28-3-2024
• Kreema A. El lebody , Rasha G. Salim, Ghada M. El-Sayed and Shaymaa H. Mahmoud. Identification and Genetic Diversity of Spodoptera frugiperda J. E. Smith (Lepidoptera: Noctuidae) in Egypt. Agronomy 2024, 14, 809. https://doi.org/10.3390/agronomy14040809
• Shaimaa A. Nour, Maha T.H. Emam, Ghada M. El-Sayed, Ebtehag A.E. Sakr. Utilizing Chitooligosaccharides from Shrimp Waste Biodegradation via Recombinant Chitinase A: A Promising Approach for Emulsifying Hydrocarbon and Bioremediation. Microb. Cell Fact. 2024 May 2;23(1):126. doi: 10.1186/s12934-024-02388-z.
• Ghada M. El-Sayed, Mona M. Agwa, Maha T.H. Emam, Heba Kandil, Ahmed E. Abdelhamid, Shaimaa A. Nour, Utilizing immobilized recombinant serine alkaline protease from Bacillus safensis lab418 in wound healing: Gene cloning, heterologous expression, optimization, and characterization, International Journal of Biological Macromolecules, 270, 2024, https://doi.org/10.1016/j.ijbiomac.2024.132286.
• El-Khamisi, E.F., Soliman, E.A.M., El-Sayed, G.M. et al. Optimization, gene cloning, expression, and molecular docking insights for enhanced cellulase enzyme production by Bacillus amyloliquefaciens strain elh1. Microb Cell Fact 23, 191 (2024). https://doi.org/10.1186/s12934-024-02454-6
• El-Sayed, G. M., Serih, A., Asar, A. M. R. I. I., Hammad, M. A. H. A., Mahmoud, S. H., & Sharaf, O. A. (2025). Recombinant Hydrolase Mediated Biodegradation of Fenamiphos by Cronobacter muytjensii GH10: Gene Cloning, Expression, and Docking Analysis. Egyptian Journal of Chemistry, 68(12), 627-640.
• Galal, F., Alshammari, F. M., Aldaghmi, A. S., Hafez, E. E., El-sayed, G., Aeban, R. H., & Alharb, S. A. A Comparison of Honeybee and Scorpion Venoms as Anticancer Agents Against three different cancer cell lines: Lung, Colon, and Breast Cancer. Frontiers in Toxicology, 8, 1756933.
• Sakr, E.A., Hassan, M.S., El Sedik, M., Rekaby, M.M. and El-Sayed, G.M., 2026. Residual-hybrid dynamic response-surface/machine-learning framework for predicting malachite green removal and biodegradation by a bacterial consortium. Journal of Biological Engineering.
• El-Ansary RE, El-Lebody KA, Aburawash RA, Mahmoud SH, El-Sayed GM, Hussein MI. Biochemical and molecular responses of Spodoptera frugiperda to insecticide exposure: detoxification enzymes, gene expression, and genotoxic effects. Sci Rep. 2026;16:12887.

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• https://orcid.org/0000-0002-0274-2927
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