WebLog Journal of Biotechnology and Biomedical Engineering

Background: Tuberculosis diagnosis remains a practical challenge in high-burden settings, where available tests have well-known limitations around sensitivity, cost, and turnaround time. Whole blood gene expression profiling offers a non-sputum-based alternative approach, but most published machine learning models in this space rely on complex pipelines or proprietary datasets. This study asked a simpler question: using publicly available microarray data and standard…

Background: Perforated Peptic Ulcer (PPU) complicated with diffuse peritonitis despite all advances of diagnosis and surgical care. The timely and precise identification of prognosis is one of the most key issues to optimize peri-operative management. In this study, the Modified Boey's Score (MBS) and the Mannheim Peritonitis Index (MPI) were compared and assessed for their predictive capabilities in patients with PPU after surgery.

Methods: A…

The properties of water and the emergence of life are interconnected phenomena. According to the hydrozoic theory of conscious perception, primordial forms of memory and awareness emerged during the early stages of biophysical evolution. The theory is based on the idea that membranes composed of phospholipid bilayer membranes and adhesive water molecules exhibit liquid crystalline properties, combining directional dependence with the mobility of the fluid mosaic model. These magnetic fields…

Hydrogels represent a class of highly versatile, three-dimensional polymer networks renowned for their exceptional water absorption capacity, biocompatibility, and tunable physicochemical properties. This review comprehensively examines the diverse landscape of hydrogels, delineating the fundamental characteristics and applications of synthetic, natural, and advanced hybrid systems. It highlights the superior mechanical strength of synthetic hydrogels and the enhanced biocompatibility of…