Henry Johannes Greten is Professor at IBA University of Cooperative Education and former Professor for Chinese Medicine as Applied Neurophysiology of the University of Porto, Portugal. He ranks No. 1 among the 100 best physicians in Germany in the category of naturopathy (Tina No. 39/2009).

He is an expert in general medicine, naturopathy, homoeopathy and acupuncture and leads the Institute of Integrative Diagnostics in Heidelberg comprising 60 employees.

He has been advocating the systematic integration of western scientific medicine and classical Chinese Medicine for years.

His scientific merits include the development of the first comprehensive medical model to explain Chinese Medicine, the introduction of double-blinding into acupuncture research, the initiation of the first master study programme of Chinese Medicine for doctors in Europe at the University of Porto and the development of a placebo for Qigong research.

He discovered three major new acupuncture systems including new acupoints for diseases like peripheral neuropathy, multiple sclerosis, orthopaedic pain and other indications, and could prove their efficacy in respective studies. He also developed new prescriptions of TCM of which several have already established themselves as new classical prescriptions.

About 130 medical publications, 26 textbooks including the standard textbook "Kursbuch Traditionelle Chinesische Medizin" (Textbook Traditional Chinese Medicine, Thieme 2017), the ”Checkliste Chinesische Phytotherapie“ (Checklist Chinese Phytotherapy, Hippokrates 2009), “Heilen mit der Intelligenz des Körpers” (Healing with the Intelligence of the Body, Ludwig 2022) and numerous book contributions.

• Chinese Medicine
• Herbs
• Cancer
• Acupuncture

• Neuroimmunomodulation – komplexes Spiel der Regelkreise (Neuroimmunomodulation – complex interactions of regulatory circuits) Greten HJ, Greten T, Spektrum Immunologie 3/89.
• Intracellular compartmentation of troponin T: release kinetics after global ischemia and calcium paradox in the isolated perfused rat heart. Remppis A, Scheffold T, Greten J, Haass M, Greten T, Kübler W, Katus HA., J Mol Cell Cardiol. 1995 Feb;27(2):793-803.
• Expression of receptors for advanced glycation end products in peripheral occlusive vascular disease. Ritthaler U, Deng Y, Zhang Y, Greten J, Abel M, Sido B, Allenberg J, Otto G, Roth H, Bierhaus A, et al, Am J Pathol. 1995 Mar;146(3):688-94.
• Expression of receptors for advanced glycosylated end-products in renal disease. Abel M, Ritthaler U, Zhang Y, Deng Y, Schmidt AM, Greten J, Sernau T, Wahl P, Andrassy K, Ritz E, et al., Nephrol Dial Transplant. 1995;10(9):1662-7.
• Prothrombin complex concentrate contains protein Z and prevents bleeding in a patient with protein Z deficiency. Greten HJ, Kemkes-Matthes B, Nawroth PP, Thromb Haemost. 1995 Sep;74(3):992-3.
• Mechanism of the tumor necrosis factor alpha-mediated induction of endothelial tissue factor. Bierhaus A, Zhang Y, Deng Y, Mackman N, Quehenberger P, Haase M, Luther T, Muller M, Bohrer H, Greten J, Martin E, Baeuerle PA, Waldherr R, Kisiel W, Ziegler R, Stern DM, Nawroth PP.,J Biol Chem. 1995 Nov 3;270(44):26419-32.
• After large studies by federal health insurance: what is the future of acupuncture? Hummelsberger J, Ernst E, Greten HJ, Bahr F. MMW Fortschr Med 2005; 147(25): 12-4.
• Receptors for advance glycation end-products (AGE)-expression by endothelial cells in non-diabetic uraemic patients. Greten J, Kreis I, Wiesel K, Stier E, Schmidt AM, Stern DM, Ritz E, Waldherr R, Nawroth PP, Nephrol Dial Transplant. 1996 May; 11(5):786-90.
• Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse meth-A sarcoma. Zhang Y, Deng Y, Wendt T, Liliensiek B, Bierhaus A, Greten J, He W, Chen B, Hach-Wunderle V, Waldherr R, Ziegler R, Männel D, Stern DM, Nawroth PP, J Clin Invest, 1996 May 15; 97(10):2213-24.
• Localisation of protein Z in vascular lesions of patients with atherosclerosis. Greten HJ, Kreis I, Liliensiek B, Allenberg J, Amiral J, Ziegler R, Nawroth PP, Vasa 1998 Aug; 27(3):144-8.
• Increased proinflammatory endothelia response to SI00A8/A9 after preactivation through advanced glycation end products. Ehlermann P, Eggers K, Bierhaus A, Most P, Weichenhan D, Greten HJ, Nawroth PP, Katus HA Remppis A, Cardiovasc Diabetol 2006, 5:6.
• In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform. Scholz EP, Alter M, Zitron E, Kiesecker C, Kathöfer S, Thomas D, Kreye VA, Kreuzer J, Becker R, Katus HA, Greten J, Karle CA. Toxicol Lett. 2006 Aug 20;165(2):156-66. Epub 2006 Mar 27.
• Differential Effect of Rhizoma Coptidis and its Main Alkaloid Compound Berberine on TNF- Induced NFkB Translocation in Human Keratinocytes. Enk R, Ehehalt R, Graham JE, Bierhaus A, Remppis A, Greten HJ, Journal of Ethnopharmacology 109 (2007) 170 – 175.
• Acupuncture Treatment Improves Nerve Conduction in Peripheral Neuropathy. Schröder S, Liepert J, Remppis A, Greten HJ, European Journal of Neurology 2007, 14: 276-281.
• Orange flavonoid hesperetin modulates cardiac hERG potassium channel via binding to amino acid F656. Scholz EP, Zitron E, Kiesecker C, Thomas D, Kathöfer S, Kreuzer J, Bauer A, Katus HA, Remppis A, Karle CA, Greten HJ, Nutrition, Metabolism&Cardiovascular Diseases (2007) 17, 666-675.
• Green tea flavonoid epigallocatechin-3-gallate (EGCG) inhibits cardiac hERG potassium channels. Kelemen K, Kiesecker C, Zitron E, Bauer A, Scholz E, Bloehs R, Thomas D, Greten J, Remppis A, Schoels W, Katus HA, Karle CA.Biochem Biophys Res Commun. 2007 Dec 21;364(3):429-35. Epub 2007 Oct 9.
• Curcumin induces apoptosis in human neuroblastoma cells via inhibition of NFkB. Freudlsperger C, Greten J, Schumacher U, Anticancer Research 28: 209-214 (2008).
• Relevance of laser irradiance threshold in the induction of alkaline phosphate in human osteoblast cultures. Haxsen V, Schikora D, Sommer U, Remppis A, Greten HJ, Kasperk C, Lasers Med Sci 2008, 23:381-384.
• Chinesische Medizin bei unerfülltem Kinderwunsch und im Klimakterium (Chinese Medicine in Fertility and Climacteric Syndromes). Osburg J, Greten HJ, Sertel S, von Hagens C, Gynäkologische Endokrinologie 2/2008. doi: 10.1007/s10304-008-0261-x.
• What is the Role of Chinese Medical Theory in Modern Scientific Research. Greten HJ, J. Acupunct. Tuina Sci. (2008),6: 259-260. doi: 10.1007/s11726-008-0259-x.
• Symptoms of “Heat” as a Pattern of Physiology. Greten HJ, Greten T, Brazkiewicz F, Sertel S, Schröder S, Goncalves M, Wendt I, Karrer O,, Mafalda A, Remppis A, J. Acupunct. Tuina Sci. (2008),6: 6.
• Acupuncture Effects on Heart Failure: How to Create Objective Study Designs. Greten HJ, Kick A, Scholz E Fischer, J, Greten T, Brazkiewicz F, Schröder S, Sertel S, Wendt I, Goncalves M, Karrer O, Remppis A, J. Acupunct. Tuina Sci. (2008) 6(5): 307-308.
• Nasal Airway Resistance Measured by Rhinomanometry: a Novel Tool to Measure Acupuncture Effects. Sertel S, Gaugel D, Choudhry A, Giannakakis K, Baumann I, Remppis A, Goncalves M, Wendt I, Greten HJ, Plinkert P; J. Acupunct. Tuina Sci. (2008),6: 9.
• Quantification of Acupuncture Effects on Peripheral Neuropathy of Unknown and Diabetic Cause by Nerve Conduction Studies. Schröder S, Remppis A, Greten T, Brazkiewicz F, Morcos M, Greten HJ; J. Acupunct. Tuina Sci. (2008),6: 312-314. doi: 10.1007/s11726-008-0312-9.
• Additional use of acupuncture to NSAID effectively reduces post-tonsillectomy pain. Sertel S, Herrmann S, Greten HJ, Haxsen, V, El-Bitar S, Simon CH, Baumann I, Plinkert PK, Eur Arch Otorhinolaryngol, 2009 Jun;266(6):919-25.
• Acupuncture for Nasal Congestion: A Prospective, Randomized, Double Blind, Placebo-Controlled Clinical Study. Sertel S, Bergmann Z, Ratzlaff K, Baumann I; Greten HJ, Plinkert PK,. Am J Rhinol Allergy. 2009, 23(6).
• Evaluation of Quality of Life in Patients Treated with Traditional Chinese Medicine. Sertel S, Greten HJ, Kraemer HJ, Efferth T, Plinkert PK, Baumann I, Open Otorhinolaryngol J, 2010,4, 62-67.
• Rhizoma Coptidis Inhibits LPS-induced MCP-1/CCL2 Production in Murine Macrophages via an AP-1 and NFB-Dependent Pathway. Remppis A, Bea F, Greten HJ, Buttler, A, Wang H, Zhou Q, Preusch MR, Enk R, Ehehalt R, Katus HA, Blessing E, Mediators Inflamm. 2010:194896. Epub 2010 Jun 21 (IF 4,774).
• Stimulation of Acupoint St 34 Acutely Improves Gait Performance in Geriatric Patients During Rehabilitation: A Randomized Controlled Trial. Hauer K, Wendt I, Schwenk M, Rohr C, Oster P, Greten HJ, Arch Phys Med Rehabil 2011 Jan;92(1):7-14 (IF 2011: 2.282).
• Chinesische Medizin als vegetative Systembiologie. Teil I: Therapeutische Verfahren (Chinese Medicine as Vegetative System Biology I. Part I: Therapeutic Methods). Greten HJ, HNO_2011 · 59:1160–1164, DOI: 10.1007/s00106-011-2409-6 (IF 2011: 0,400).
• Chinesische Medizin als vegetative Systembiologie. Teil II: Die Struktur der TCM-Diagnose (Chinese Medicine as Vegetative System Biology. Part II: The structure of Chinese diagnosis). Greten HJ, HNO_2011 · 59:1165–1175, DOI: 10.1007/s00106-011-2413-x (IF 2011: 0,400).
• Molecular Determinants of the Response of Tumor Cells to Boswellic Acids. Eichhorn T, Greten HJ, Efferth T. Pharmaceuticals 2011, 4(8), 1171-1182.
• Self-medication with nutritional supplements and herbal over-the-counter products. Eichhorn T, Greten HJ, Efferth T. Nat. Prod. Bioprospect 2011, 1, 62-70.
• Anti-Inflammatory and Anti-Cancer Activity of Boswellic Acids from Frankincense (Boswellia serrata Roxb. et Colebr, B. carterii Birdw.). Efferth T, Greten HJ. Forum on Immunopathological Diseases and Therapeutics. 2(4):303-313 (2011).
• Microarray-Based Determination of Response of Tumor Cells to Cycloshikonin. Efferth T, Greten HJ. Forum on Immunopathological Diseases and Therapeutics. 2(4):315-322 (2011).
• Effects of Scrophularia ningpoensis Hemsl. on inhibition of proliferation, apoptosis induction and NF-kB signaling of immortalized and cancer cell lines. Shen X, Eichhorn T, Greten HJ, Thomas Efferth T. Pharmaceuticals 2012, 5, 189-208.
• Can Heat and Cold be Parametrized? Clinical Data of a Preliminary Study. Doenitz C, Anjos, A, Efferth T, Greten T, Greten HJ. JCIM 2012; 10(5):532-7.
• Assessment of Qigong-Related effects by Infrared Thermography: A Case Study. Matos LC, Gonçalves M, Machado J, Greten HJ. JCIM 2012; 10(6):663-666.
• Medicinal and Aromatic Plant Research in the 21st Century. Efferth T, Greten HJ. Medicinal Aromatic Plants 2012. 1:2. doi 10.4172/2167-0412.1000e110.
• The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies? Efferth T, Greten HJ. JCIM 2012; 10(4):357-61; doi: 10.3736/jcim20120401.
• In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides. Efferth T, Greten HJ. Microarrays Basel, May 22;1(1):44-63. doi: 10.3390/microarrays1010044.
• Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren - A Feasibility Study – Sousa CM, Gonçalves M, Machado J, Efferth T, Greten T, Froeschen P, Greten HJ. JCIM 2012; 10(8):858-65.
• Qigong Therapy in Physiotherapists in Burnout – A Preliminary Study. Saganha JP, Doenitz CA, Greten T, Efferth T, Greten HJ, 2012, JCIM 2012; 10(11): 1233-9: PMID: 23158941.
• Quality Control for Medicinal Plants. Efferth T, Greten HJ, Med Aromat Plants 2012, 1:7. doi.org/10.4172/2167-0412.1000e131.
• Autophagy by Natural Products in Cancer Cells. Efferth T, Greten HJ, Biochem Anal Biochem 2012. 1:8. doi.org/10.4172/2161-1009.1000e128.
• Objectifying specific and non-specific effects of acupuncture: A double-blinded, randomised trial in osteoarthritis of the knee. Karner M, Brazkiewicz F, Remppis A, Fischer J, Gerlach O, Stremmel W, Subramanian SV, Greten HJ. Evid Based Complement Alternat Med, 2013, http://dx.doi.org/10.1155/2013/427265 (IF 4,774).
• Animal plant warfare and secondary metabolite evolution. Wöll S, Hee Kim SH, Greten HJ, Efferth T. Nat. Prod. Bioprospect. 2013,,DOI 10.1007/s13659-013-0004-0.
• Objectifying acupuncture effects by lung function and numeric rating scale in patients undergoing heart surgery. Maimer A, Remppis A, Sack FU, Greten T, Brazkiewicz F, Schröder S, Goncalves M, Efferth T, Greten HJ. Evid Based Complement Alternat Med, 2013, http://dx.doi.org/10.1155/2013/219817 (IF 4,774).
• Mechanisms of Herb-Induced Nephotoxicity. Allard T, Wenner T, Greten HJ, Efferth T. Curr Med Chem. 2013 Apr 12. PMID: 23597204.
• Are conduits superconductor-like and supported by by tetrahedra structure of hyaluronic matrix in living systems? New perspectives. R. Fromknecht R, Goncalves M, Greten HJ, Machado J. J Complement Integr Med. 2013; 10(1): 1-5.
• Cytotoxicity and pharmacogenomics of medicinal plants from traditional Korean medicine. Kuete V, Ean-Jeong Seo EJ, Krusche B, Oswald M, Wiench B, Schroeder S, Greten HJ, Lee IS, Efferth T Evid Based Complement Alternat Med, 2013 http://dx.doi.org/10.1155/2013/341724 (IF 1.722).
• Diagnosis and Objective Pain Assessment of Traditional Chinese Medicine May Be Useful to Demonstrate Specific Effects of Acupuncture in Low Back Pain- A Prospective, Randomized, Controlled and Single-Blinded Pre-Study. Seca S, Capelo P, Efferth T, Doenitz CA, Schroeder S, Anjos A, Machado J, Greten HJ. J Acupunct. Tuina Sci 2013, 11(3): 155-159, doi 10.1007/s11726-013-0679-0.
• Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy- Induced Peripheral Neuropathy (CIPN)? Schroeder S, Beckmann K, Franconi G, Meyer-Hamme G, Friedemann T, Greten HJ, Rostock M and Efferth T. Evid Based Complement Alternat Med, 2013. http://dx.doi.org/10.1155/2013/423713 (IF 1.772).
• Anti-angiogenic activity and pharmacogenomics of medicinal plants from traditional Korean medicine. Seo EJ, Kuete V, Kadioglu O, Krusche B, Schroeder S, Greten HJ, Arend J, Lee IS, Efferth T. Evid Based Complement Alternat Med 2013, http://dx.doi.org/10.1155/2013/131306 (IF 1,772).
• A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-induced Oral Mucositis. Meyer-Hamme G, Beckmann K, Efferth T, Radtke J, Greten HJ, Rostock M, Schroeder S. Evid Based Complement Alternat Med 2013, http://dx.doi.org/10.1155/2013/284959 (IF 1.772).
• Animals and Animal Toxins in Traditional and Modern Medicine. Kaufmann A, Greten HJ, Efferth T. British Journal of Applied Science & Technology 4(4): 578-593, 2014 (IF 4.5).
• Pharmacogenomics of cantharidin in tumor cells. Kadioglu O, Kermani NS, Kelter G, Schumacher U, Fiebig HH, Greten HJ, Efferth T. Biochem Pharmacol 87 (2014) 399-409 (IF 4.576).
• Effects of Acupuncture on Leucopenia, Neutropenia, NK and B Cells in Cancer Patients: A Randomised Pilot Study. Pais, I, Correia N, Pimentel I, Teles MJ, Neves E, Vasconcelos J, Guimarães J, Azevedo N, Moreira Pinto A, Machado J, Efferth T, Greten HJ (Evid Based Complement Alternat Med June 2014 (IF 1.722).
• Traditional Medicine with Plants – Present and Past. Efferth T, Greten HJ, Med Aromat Plants 2014, 3:3, http://dx.doi.org/10.4172/2167-0412.1000e151.
• The Prevalence of Playing-Related Musculoskeletal Disorders (PRMSD) Among Professional Orchestra Players. Sousa CM, Greten HJ, Machado J, Coimbra D, Revista Música Hodie,V.14, n.2. 2014.
• Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking. Saeed M, Kuete V, Kadioglu O, Börtzler J, Khalid H, Greten HJ, Efferth T, Phytomedicine. 2014 Oct 15;21(12): 1525-33. doi: 10.1016/j.phymed.2014.07.011. Epub 2014 Aug 28.
• Identification of Cellular and Molecular Factors Determining the Response of Cancer Cells to Six Ergot Alkaloids. Mrusek M, Seo EJ, Greten HJ, Simon M, Efferth T, Invest New Drugs (2015) 33:32-44, DOI 10.1007/s10637-014-0168-4.
• Targeting epidermal growth factor receptors and downstream signalling pathways in cancer by phytochemicals. Kadioglu O, Cao J, Saeed M, Greten HJ, Efferth T, Target Oncol (2015) 10:337-353, DOI 10.1007/s11523-014.0339-4.
• Dis-organizing centrosomal clusters: specific cancer therapy for a generic spread? Bhakta-Guha D, Saeed ME, Greten HJ, Efferth T, Curr Med Chem. 2015;22(6):685-94.
• Pharmacogenomic and molecular docking studies on the cytotoxicity of the natural steroid wortmannin against multidrug-resistant tumor cells. Kuete V, Saeed ME, Kadioglu O, Börtzler J, Khalid H, Greten HJ, Efferth T, Phytomedicine. 2015 Jan 15; 22(1): 120-7. doi: 10.1016/j.phymed.2014.11.011. Epub 2014 Nov 26.
• Aptamers as a novel tool for diagnostics and therapy. Kadioglu O, Malczyk AH, Greten HJ, Efferth T, Invest New Drugs, DOI 10.1007/s10637-015-0213-y, Epub 2015 Feb 1.
• Laurus nobilis L. Seed Extract Reveals Collateral Sensitivity in Multidrug-Resistant P-Glycoprotein-Expressing Tumor Cells. Saab AM, Guerrini A, Zeino M, Wiench B, Rossi D, Gambari R, Sacchetti G, Greten HJ, Efferth T, Nutr Cancer. 2015;67(4):664-75. doi: 10.1080/01635581.2015.1019632. Epub 2015 Apr 2.
• Cytotoxicity of medicinal plants of the West-Canadian Gwich’in Native Americans towards sensitive and multidrug-resistant cancer cells. Karadeniz A, Alexie G, Greten HJ, Andersch K, Efferth T, J Ethnopharmacol 168 (2015)191-200.
• Quantitative structure-activity relationship and molecular docking of artemisinin derivatives to vascular endothelial growth factor receptor 1. Saeed ME, Kadioglu O, Seo EJ, Greten HJ, Brenk R, Efferth T, Anticancer Res. 2015 Apr;35(4):1929-34.
• Qigong as a Traditional Vegetative Biofeedback Therapy: Long-Term Conditioning of Physiological Mind-Body Effects. Matos LC, Sousa CM, Goncalves M, Gabriel J, Machado J, Greten HJ, BioMed Research International, vol. 2015, Article ID 531789, 6 p. 2015. doi:10.1155/2015/531789.
• Immediate Effects of Tuina Techniques on Working-Related Musculoskeletal Disorder of Professional Orchestra Musicians. Sousa CM, Moreira L, Coimbra D, Machado J, Greten HJ, J Integr Med. 2015; 13(4): 257-261.
• Effects of self-administered exercises based on Tuina techniques on musculoskeletal disorders of professional orchestra musicians: a randomized controlled trial. Sousa CM, Coimbra D, Machado J, Greten HJ, J Integr Med. 2015; 13(5): 314-318.
• Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells. Ooko E, Saeed M, Kadioglu O, Sarvi S, Colak M, Elmasaoudi K, Janah R, Greten HJ, Efferth T, Phytomedicine 22 (2015) 1045-1054.
• Occupational Diseases of Professional Orchestra Musicians form Northern Portugal. A Descriptive Study. Sousa CM, Machado J, Greten HJ, Coimbra D. Med Probl Perform Art. 2016 Mar;31(1):8-12. doi: 10.21091/mppa.2016.1002.
• Biopiracy of natural products and good bioprospecting practice. Efferth T, Banerjee M, Paul NW, Abdelfatah S, Arend J, Elhassan G, Hamdoun S, Hamm R, Hong C, Kadioglu O, Naß J, Ochwangi D, Ooko E, Ozenver N, Saeed ME, Schneider M, Seo EJ, Wu CF, Yan G, Zeino M, Zhao Q, Abu-Darwish MS, Andersch K, Alexie G, Bessarab D, Bhakta-Guha D, Bolzani V, Dapat E, Donenko FV, Efferth M, Greten HJ, Gunatilaka L, Hussein AA, Karadeniz A, Khalid HE, Kuete V, Lee IS, Liu L, Midiwo J, Mora R, Nakagawa H, Ngassapa O, Noysang C, Omosa LK, Roland FH, Shahat AA, Saab A, Saeed EM, Shan L, Titinchi SJ.Phytomedicine. 2016 Feb 15;23(2):166-73. doi: 10.1016/j.phymed.2015.12.006. Epub 2016 Jan 9. Review.
• Antischistosomal activity of artemisinin derivatives in vivo and in patients. Saeed ME, Krishna S, Greten HJ, Kremsner PG, Efferth T. Pharmacol Res. 2016 Feb 21. pii: S1043-6618(15)30158-4. doi: 10.1016/j.phrs.2016.02.017. [Epub ahead of print] IF 4,8.
• Pharmacogenomics of Scopoletin in Tumor Cells. Seo EJ, Saeed M, Law BYK, Wu AG, Kadioglu O, Greten HJ, Efferth T. Molecules 2016, 21(4), 496; doi: 10.3390/molecules21040496.
• Doctrine of Signatures – Mystic Heritage or Outdated Relict from Middle-Aged Phytotherapy? Efferth T, Greten HJ. Med Aromat Plants 2016. 5:4. http://dx.doi.org/10.4172/2167-0412.1000e177.
• Evaluation of the effect of acupuncture on hand pain, functional deficits and health-related quality of life in patients with rheumatoid arthritis – A study protocol for a multicenter, double-blind, randomized clinical trial. Seca S, Kirch S, Cabrita AS, Greten HJ. J Integr Med. 2016 May;14(3):219-27. doi: 10.1016/S2095-4964(16)60254-6.
• The effectiveness of acupuncture on hand pain, physical function and health-related quality of life in patients with rheumatoid arthritis: a systematic review protocol. Seca S, Miranda D, Cardoso D, Greten H, Cabrita A, Rodrigues MA. JBI Database System Rev Implement Rep. 2016 May; 14(5): 18-26. doi: 10.11124/JBISRIR-2016-002543.
• The acute effect of Tuina on hand grip muscle fatigue and strength – Preliminary study. Beshoy G, SantosMJ, Ramos B, Laranjeira M, Reis AM, Greten HJ, Jorge Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 171-174.
• Effect of Acupuncture on delayed onset muscle soreness: series of case studies. Cardoso R, Lumini-Oliveira J, Santos MJ, Bruno Ramos, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 85-92.
• The effect of QiGong on Attention: Deficit-Hyperactivity Disorder (ADHD): Clinical Case Report. Correia MC, Greten HJ, Machado J, Gonçalves M. Experimental Pathology and Health Sciences, 2016;8 (2) 29-34.
• The effect of QiGong in natural killer cells in colo-rectal cancer patients undergoing chemotherapy - A protocol study. Costa, S, Pais I, Araújo A, Gonçalves M, Santos MJ, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 47-54.
• Acupuncture treatment on gait problems in multiple sclerosis: a preliminary study. Criado MB, Santos MJ, Laranjeira M, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 171-174131-134.
• Effect of acupuncture on hand pain in patients with rheumatoid Arthritis - Clinical research protocol. Fernandes M, Seca S, Gabriel J, Correia R, Santos MJ, Cabrita A, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 125-130.
• Can acupuncture in S34 improve postural stability in healthy subjects? Fernandes T, Carvalho L, Santos MJ, Ramos B, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 105-110.
• Can acupoint S34 influence kick performance in kickboxers? A prospective study. Ferreira S, Machado L, Santos MJ, Moreira S, Ramos B, Cabrita A, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 159-166.
• Acute Effects of Puncture Technique on Temporomandibular Dysfunction: preliminary study. Gomes P, Santos MJ, Martins dos Santos J, Ramos B, Carvalho L, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 135-140.
• Immediate Effect of Acupuncture on Post-Operative Pain After Lumbar Surgery. Hamza F, Anjos A, Santos MJ, Ramos B, Reis AM, Greten HJ, Machado J, Manuel Laranjeira M. Experimental Pathology and Health Sciences, 2016;8 (2) 115-118.
• Acupuncture effect on gastric myoelectric activity: experimental protocol. Martins S, Santos MJ, Ramos B, Gabriel J, Correia R, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 167-170.
• Does acupuncture improve strength and nerve conduction in RA patients with hand affection? A protocol study. Miranda D, Seca S, Ramos B, Laranjeira M, Cabrita A, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 93-98.
• The immediate effects of acupuncture on the kickboxer postural balance: an exploratory randomised trial. Moreira S, Machado L, Santos MJ, Araújo S, Ramos B, Cabrita A, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 153-158.
• Efficacy of Qigong on depression: From a systematic literature review to the proposal of a study protocol. Pereira P, Santos MJ, Laranjeira M, Gonçalves M, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 35-40.
• Potential effects of medical QiGong in major depressive disorder: study protocol based on clinical cases. Ponte S, Santos MJ, Paiva C, Laranjeira M, Gonçalves M, Ramos B, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 41-46.
• A Traditional Chinese Medicine Master Program in a public university: education and research. Santos MJ, Nuno Correia N, Diana Miranda D, Petra Froeschen, P, A. Mafalda Reis AM, Manuel Laranjeira M, Henry Johannes Greten HJ, Jorge Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 21-24.
• Prospective study on a new acupuncture strategy in obstructive sleep apnoea. Santos MJ, CorreiaN, Sá M, Winck JC, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 143-146.
• Treating musculoskeletal pain with Traditional Chinese Medicine techniques – A short review. Sousa C, Gonçalves M, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 25-28.
• Vegetative Functions Induced by Music: A preliminary study. Sousa S, Santos MJ, Machado J, Greten HJ. Experimental Pathology and Health Sciences, 2016;8 (2) 175-178.
• Lowering anxiety of university students prior to the exams by ear acupuncture – Preliminary study. Vieira A, Silva K, Hinzmann M, Stürmer J, Santos MJ, Correia N, Greten HJ, Machado J. Experimental Pathology and Health Sciences, 2016;8 (2) 147-152.
• Neuroprotection and antioxidative effects of Sijunzi TangDecoction in the nematode Caenorhabditis elegans. Schlotterer A, Greten HJ, Remppis BA, Kukudov G, Efferth T, Machado J, Humpert P, Hammes HP, Morcos M. EuJIM 10.1016/j.eujim.2016.03.009.
• Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin - Two Msin Metabolites of Curcuma longa in Cancer Cells. Ooko E, Kadioglu O, Greten HJ, Efferth T. Front Pharmacol 2017. doi: 10.3389/fphar.2017.00038.
• Effects of Acupuncture on Gait of Patients with Multiple Sclerosis. Criado MB, Santos MJ, Machado J, Gonçalves AM, Greten HJ. J Altern Complement Med 2017; doi 10.1089/acm.2016.0355.
• Playing-related Musculoskeletal Disorders of Professional Orchestra Musicians from the North of Portugal: Comparing String and Wind Musicians. Sousa CM, Machado J, Greten HJ, Coimbra D. Acta Med Port 2017; 30(4):302-306. doi.org/10.20344/amp.7568.
• Instrumental Measurements of Water and the Surrounding Space During a Randomized Blinded Controlled Trial of Focused Intention. Matos LC, Santos SC, Anderson JG, Machado J, Greten HJ, Monteiro FJ. J Evid Based Complementary Altern Med 2017. doi:10.1177/2156587217707117.
• The immediate effects of acupuncture on the mechanosensitivity of the median nerve: an exploratory randomised trial. Morais NV, Greten HJ, Santos M, Machado J. Acupunct Med. 2018 Jun;36(3):132-138. doi: 10.1136/acupmed-2016-011357. Epub 2018 May 2.
• New Pressure Algometry Device for the Quantification of Acupuncture Induced Pain. Seca S, Miranda D, Patricio M, Correia R, Kirch S, Cabrita AS, Greten HJ, J. Altern Complement Integr Med 2017. doi: 10.24966/ACIM-7562/100019.
• ACUDIN – ACUpuncture and laser acupuncture for treatment of DIabetic peripheral Neuropathy: a randomized, placebo-controlled, partially double-blinded trial. Meyer-Hamme G, Friedemann T, Greten HJ, Plaetke R, Gerloff C, Schroeder S. BMC Neurol. 2018 Apr 13;18(1):40. doi: 10.1186/s12883-018-1037-0.
• Oridonin Targets Multiple Drug-Resistant Tumor Cells as Determined by in Sicico and in Vitro Analyses. Kadioglu O, Saeed M, Kuete V, Henry J. Greten HJ, Efferth T. Front Pharmacol 2018, doi: 10.3389/fphar.2018.00355 (IF 4.4).
• Chinese Medicine functional diagnosis: an integrative insight to understand Rheumatoid Arthritis of the hand. Seca S, Patrício M, Kirch S, Franconi G, Cabrita AS, Greten HJ. Eur J Integr Med 2018. doi:10.1016/j.eujim.2018.07.005.
• Effectiveness of acupuncture on pain, functional disability and quality of life on rheumatoid arthritis of the hand – results of a double-blind randomized clinical trial. Seca S, Patrício M, Kirch S, Franconi G, Cabrita AS, Greten HJ J Altern Complement Med - Published Online: 16 Oct 2018 https://doi.org/10.1089/acm.2018.0297.
• Repurposing of bromocriptine for cancer therapy. Seo EJ, Sugimoto Y, Greten HJ, Efferth T. Front. Pharmacol.08 October 2018, doi: 10.3389/fphar.2018.01030.
• Biopiracy versus One-World Medicine–From colonial relicts to global collaborative concepts. Efferth T, Banerjee M, Abu-Darwish MS, Abdelfatah S, Böckers M, Bhakta-Guha D, Bolzani V, Daak S, Demirezer ÖL, Dawood M, Efferth M, El-Seedi HR, Fischer N, Greten HJ, Hamdoun S, Hong C, Horneber M, Kadioglu O, Khalid HE, Khalid SA, Kuete V, Mahmoud N, Marin J, Mbaveng A, Midiwo J, Nakagawa H, Naß J, Ngassapa O, Ochwang'i D, Omosa LK, Ooko EA, Özenver N, Poornima P, Rodriguez Romero M, Saeed MEM, Salgueiro L, Seo EJ, Yan G, Yasin Z, Saeed EM, Paul NW. Available online 11 June 2018¸ https://doi.org/10.1016/j.phymed.2018.06.007.
• Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation. Mahmoud N, Saeed MEM, Sugimoto Y, Klauck SM, Greten HJ, Efferth T. Oncotarget, 2018. Vol. 9 (No. 87). pp. 35762-35779.
• Effectiveness of Acupuncture on Pain, Physical Function and Health-Related Quality of Life in Patients with Rheumatoid Arthritis: A Systematic Review of Quantitative Evidence. Seca, S, Miranda D, Cardoso D, Nogueira B, Greten HJ, Cabrita A, Rodrigues MA. Chin J Integr Med. 2018 Dec 19. doi: 10.1007/s11655-018-2914-x. [Epub ahead of print].
• MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate. Abdelfatah S, Berg, A, Huang Q, Yang LJ, Hamdoun S, Klinger A, Greten HJ, Fleischer E, Berg T, Wong VKW, Efferth T. Acta Pharmaceutica Sinica B (2019), https://doi.org/10.1016/j.apsb.2019.02.001.
• Changes of Skin Electrical Potential in Acupoints from Ren Mai and Du Mai Conduits During Qigong Practice: Documentation of a Clinical Phenomenon. Matos, CM, Machado J, Greten HJ, Monteiro FJ. J Bodyw Mov Ther, 23 (4), 713-720, Oct 2019, DOI: 10.1016/j.jbmt.2019.02.021.
• Can Qigong improve attention in adolescents? A prospective randomised controlled trial. Duarte L, Gonçalves M, Mendes P, Matos LC, Greten HJ, Machado J. JP. J Bodyw Mov Ther, May 2019 DOI: https://doi.org/10.1016/j.jbmt.2019.05.005.
• Electrophysiologically verified effects of acupuncture on diabetic peripheral neuropathy in type 2 diabetes: The randomized, partially double‐blinded, controlled ACUDIN trial. Meyer-Hamme G, Friedemann T, Greten HJ, Gerloff C, Schröder S. Journal of Diabetes 2020. In press. DOI: 10.1111/1753-0407.13130.
• Identification of Novel Rare ABCC1 Transporter Mutations in Tumor Biopsies of Cancer Patients. Kadioglu O, Saeed M, Munder M, Spuller A, Greten HJ, Efferth T. Cells 2020, 9, 299; doi:10.3390/cells9020299.
• Can measurements be physically conditioned by thought? Further observations following a focused intention experiment. Matos LC, Santos SC, Anderson JG, Machado J, Greten HJ, Monteiro FJ. J Complement Integrat Med, online 31.03.2020; DOI: 10.1515/jcim-2017-0056.
• Can the electrical potential of acupoints be used to assess the functional state of meridians and the effects of therapeutics? An exploratory data analysis. Matos LC, Lopes L, Freire V, Machado J, Monteiro FJ, Greten HJ. J. Bodyw. Mov. Ther. 2020; doi 10.1016/j.jbmt.2020.12.038.
• Identification of novel compounds against three targets of SARS CoV2 coronavirus by combined virtual screening and supervised machine learning. Kadioglu O, Saeed M, Greten HJ, Efferth T. Bull World Health Organ. E-pub 21 March 2020. Doi: http://dx.doi.org/10.2471/BLT.20.255943. Comput Biol Med 2021 Jun;133:104359. doi: 10.1016/j.compbiomed.2021.104359. Epub 2021 Mar 30.
• G1-5 Syndromes, a Novel Model of Diagnosis of Upper Abdominal Syndromes and their Treatment. Santos MJ, Moura A, Machado J, Morcos M, Greten HJ, Froeschen P. Biomedical Journal of Scientific & Technical Research May 2020, doi 10.26717/BJSTR.2020.26.004362.
• Problems of Scientific Methodology Related to Placebo Control in Qigong Studies: A Systematic Review. Goncavles M, Matos LC, Duarte L, Machado J, Greten HJ, Franconi G. J Bodyw Mov Ther, 2020. https://doi.org/10.1016/j.jbmt.2020.06.035.
• Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells. Kadioglu O, Saeed M, Greten HJ, Mayr K, Schrama D, Roos WP, Efferth T. July 2020, Journal of the American Academy of Dermatology, DOI: 10.1016/j.jaad.2020.07.069 – proof – online ahead of print
• Effect of ABC transporter expression and mutational status on survival rates of cancer patients. Kadioglu O, Saeed MEM, Munder M, Spuller A, Greten HJ, Efferth T. Sep 2020, Biomedicine & pharmacotherapy = Biomedicine & Pharmacotherapy https://doi.org/10.1016/j.biopha.2020.110718.
• Genomic landscape analyses in cervical carcinoma and consequences for treatment. Diefenbach D, Greten HJ, Efferth T. COPHAR 2020, 54:142-157. https://doi.org/10.1016/j.coph.2020.09.013.
• Acupuncture can be beneficial for exercise-induced muscle soreness: A randomised controlled trial. Cardoso R, Lumini-Oliveira JA, Santos MJ, Ramos B, Matos LC, Machado J, Greten HJ, Franconi G. J Bodyw Mov Ther 2020 Jan;24(1):8-14. doi: 10.1016/j.jbmt.2019.03.015. Epub 2019 Apr 4.
• Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma. Saeed MEM, Kadioglu O, Greten HJ, Yildirim A, Mayr K, Wenz F, Giordano FA, Efferth T. Invest New Drugs. 2020 Dec 12. doi: 10.1007/s10637-020-01037-7. Online ahead of print.
• Can Traditional Chinese Medicine Diagnosis Be Parameterized and Standardized? A Narrative Review. Matos LC, Machado J, Monteiro FJ, Greten HJ. Healthcare 2021, doi.org/10.3390/healthcare9020177.
• Understanding Traditional Chinese Medicine Therapeutics: An Overview of the Basics and Clinical Applications. Matos LC, Machado J, Monteiro FJ, Greten HJ. Healthcare 2021. 9, 257. Doi.org/10.3390/healthcare9030257.
• Perspectives, Measurability and Effects of Non-Contact Biofield-Based Practices: A Narrative Review of Quantitative Research. Matos LC, Machado J, Monteiro FJ, Greten HJ. Int. J. Environ. Res. Public Health 2021, 18, 6397doi.org/10.3390/ijerph18126397.
• Acupuncture improves chemotherapy-induced neuropathy explored by neurophysiological and clinical outcomes - the randomized, controlled, cross-over ACUCIN trial. Friedemann T, Kark E, Cao N, Klaßen M, Meyer-Hamme G, Greten HJ, Rostock M, Buhlmann E, Zhao A, Schröder S. Phytomedicine 2022, https://doi.org/10.1016/j.phymed.2022.154294.
• Qigong for the Emotional Exhaustion in Nurses: Implications of a Prospective Randomized Controlled Trial in the COVID-19 Pandemic. Seiça A, Gonçalves M, Magalhães J, Jorge Machado J, Rodrigues J, Greten HJ. Altern Ther Health Med. 2022 online ahead of print. PMID 35951067.
• Effectiveness of Acupuncture in Parkinson’s Disease Symptoms – A Systematic Review. Pereira C, Machado J, Rodriques J, Oliveira NM, Criado MB, Greten HJ, healthcare 2022, doi.org/10.3390/healthcare10112334.
• Qigong in Perceptual Auditory Attention: Tool to Improve Sound Integration in Autism Spectrum Disorders. Lopes L, Matos LC, Gonçalves M, Ramos B, Santos MJ, Machado J, Greten, HJ. Adv Mind Body Med 2022;36(3):4-11. PIMD:36308504.
• Checkpoint acupuncture as a novel complementary tool to address postoperative pain within the ERAS®-pathway for abdominal surgery. Ghanad E, Yang C, Weiß C, Machado J, Gonçalves M, Otto M, Reißfelder J, Greten HJ, Herrle F, Clinical Nutrition ESPEN 2022. doi: 10.1016/j.clnesp.2022.06.052.
• The effect of manual acupuncture on postoperative pain and recovery from abdominal surgery: A systematic review. Staff S, Yang C, Ghanad E, Greten HJ, Reißfelder J, Herrle F, Clinical Nutrition ESPEN 2022. doi: 10.1016/j.clnesp.2022.06.083.
• Pain therapy within the ERAS concept – Creating objectivity in studies on personalized checkpoint acupuncture. Ghanad E, Machado J, Santos MJ, Gonçalves M, Reißfelder, Herrle F, J, Greten HJ, Clinical Nutrition ESPEN 2022. doi: 10.1016/j.clnesp.2022.06.104.
• A drug repurposing approach for individualized cancer therapy based on transcriptome sequencing and virtual drug screening. Kadioglu O, Bahramimehr F, Dawood M, Mahmoud N, Elbadawi M, Lu X, Bülbül Y, Schulz JA, Krämer L, Urschel MK, Künzli Z, Abdulrahman L, Aboumaachar F, Kadalo L, Nguyen LV, Shaidaei S, Thaher N, Walter K, Besler KC, Spuller A, Munder M, Greten HJ, Efferth T, Comp. Bio. Med. 2023, doi.org/10.1016/j.compbiomed.2023.106781.
• Reduction of Pain After Laparoscopic Bariatric Surgery by Personalized Checkpoint Acupuncture-Data of a STRICTA Conform Pilot Study. Ghanad E, Staff S, Weiß C, Goncalves M, Santos MJ, Correia N, Vassilev G, Herrle F, Reissfelder C, Greten HJ, Otto M, Yang C. Obes Surg 2023 May 29. doi: 10.1007/s11695-023-06654-8. Online ahead of print.
• Can Qigong Be a Tool to Assist Students in Handling COVID-19’s Resulting Academic Stress? Goncalves M, Duarte L, Rodrigues J, Greten HJ, Machado J. Healthcare 2023, doi.org/10.3390/healthcare11030307.
• Qigong for the Mental Health of Teachers – A Prospective Randomized Controlled Trial. Goncalves M, Oliveira R, Rodrigues J, Ventura C, Machado J, Greten HJ, Brain Behav Immun 2023, doi.org/10.1016/j.bbii.2023.100018.
• Personalized checkpoint acupuncture can reduce postoperative pain after abdominal surgery—a STRICTA‑conform pilot study. Ghanad E, Yang C, Weiß C, Goncalves M, Santos MJ, Correia N,·Reissfelder C, Greten HJ, Herrle F. Langenbecks Arch Surg. 2023 Oct 10;408(1):391. doi: 10.1007/s00423-023-03051-8.
• A systematic review of the effectiveness of acupuncture in Parkinson's disease symptoms. Pereira C, Machado J, Oliveira N, Rodrigues J, Criado M, Greten HJ. J. Neurol. Sci. 2023 https://doi.org/ 10.1016/j.jns.2023.121792.
• Can acupuncture increase microcirculation in peripheral artery disease and diabetic foot syndrome? – a pilot study. Valentini J, Sigl M, Dunckel C, Krisam J, Amendt K and Greten HJ (2024) Front. Med. 11:1371056. doi: 10.3389/fmed.2024.1371056.

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