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Talha Umar

Postdoctoral Researcher

Present

Wuhan

China

Huazhong Agriculture University Wuhan

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I completed my master's degree in clinical veterinary medicine at Huazhong Agricultural University, Wuhan P.R.China and I am currently pursuing my Ph.D. studies at the same institution. My research encompasses a comprehensive understanding of Endometritis, Acute Lung Injury caused by LPS, and innovative investigations into the molecular mechanisms of lncRNAs in treating ulcerative injuries of the endometrium induced by potassium permanganate. With a foundation in Clinical Veterinary Medicine from Huazhong Agricultural University, I am committed to advancing scientific knowledge and promoting scholarly excellence within the veterinary field.

  • Endometritis
  • LPS
  • KMnO4
  • miRNAs
  • LncRNAs
  • mRNAs
  • Acute Lung Injury
  • Oxidative Stress
  • Inflammation
  • Pregnancy
  • Uterine Infections
  • Traditional Chinese Medicine (TCM)
  • Bovines
  • Mice
  • Talha Umar, Liu Wenjing, Huili Feng, Wen Feng, Ma Bin, Zaima Umar, Muhammad Naeem, Abdul Sami Umar, Sana Asif, Muhammad Usman, & Deng Ganzhen (2024). A Review on the Applications of Potassium Permanganate in Veterinary Medicine: Toxicity, Efficacy and Future Considerations.(Pakistan Veterinary Journal, I.F= 2.3)
  • Talha Umar, Baoyi Yin, Saqib Umar, Xiaofei Ma, Zaima Umar, Ganzhen Deng (2022).MiR-424-5p mediates the negative regulation of NF-κB pathway in lipopolysaccharide induced endometritis by targeting IRAK2. (Reproduction Immunology, I.F= 3.4)
  • Talha Umar1, Baoyi Yin1, Lixin He,Wen Feng, Yongjie Yuan, Saqib Umer, Huili Feng, Zhi Huang, Zaima Umar, Wenjing Liu, & Deng Ganzhen (2022). 6‑Gingerol via overexpression of miR‑322‑5p impede lipopolysaccharide‑caused inflammatory response in RAW264.7 cells.(Naunyn-Schmiedeberg's Archives of Pharmacology, I.F=3.6)
  • Baoyi Yin1, Talha Umar1, Xiaofei Ma, Yu Chen, Zaima Umar, Saqib Umar, Ganzhen Deng (2022).Andrograpanin mitigates Lipopolysaccharides induced endometritis via TLR4/NF-κB pathway.(Reproductive Biology, I.F=2.1)
  • Talha Umar, Baoyi Yin, Saqib Umar, Xiaofei Ma, Zaima Umar, Ganzhen Deng (2021). MicroRNA: Could it play a role in Bovine Endometritis? (Inflammation, I. F= 5.1)
  • Baoyi Yin; Talha Umar; Xiaofei Ma; Yu Chen; Nuoer Chen; Ganzhen Deng (2021). MiR-193a-3p targets LGR4 to promote the inflammatory response in endometritis. (International Immunopharmacology, I.F 5.6)
  • Xiaofei Ma, Baoyi Yin, Shuai Guo, Talha Umar, Junfeng Liu, Zhimin Wu, Qingqing Zhou, Arshad Zahoor, Ganzhen Deng(2021). Enhanced Expression of miR-34a Enhances Escherichia coli Lipopolysaccharide-Mediated Endometritis by Targeting LGR4 to Activate the NF-κB Pathway.(Oxidative medicine and cellular longevity IF=6.5)
  • Akhtar, M., Shaukat, A., Zahoor, A., Chen, Y., Wang, Y., Yang, M., Umar, T., Guo, M., & Deng, G. (2019). Anti-inflammatory effects of Hederacoside-C on Staphylococcus aureus induced inflammation via TLRs and their downstream signal pathway in vivo and in vitro. Microbial pathogenesis, 137, 103-767. https://doi.org/10.1016/j.micpath.2019.103767
  • Shaukat, A., Guo, Y. F., Jiang, K., Zhao, G., Wu, H., Zhang, T., Yang, Y., Guo, S., Yang, C., Zahoor, A., Akhtar, M., Umar, T., Shaukat, I., Rajput, S. A., Hassan, M., & Deng, G. (2019). Ginsenoside Rb1 ameliorates Staphylococcus aureus-induced Acute Lung Injury through attenuating NF-κB and MAPK activation. Microbial pathogenesis, 132, 302–312. https://doi.org/10.1016/j.micpath.2019.05.003
  • Akhtar, M., Shaukat, A., Zahoor, A., Chen, Y., Wang, Y., Yang, M., Umar, T., Guo, M., & Deng, G. (2020). Hederacoside-C Inhibition of Staphylococcus Aureus-Induced Mastitis via TLR2 & TLR4 and Their Downstream Signaling NF-κB and MAPKs Pathways In Vivo and In Vitro. Inflammation, 43(2), 579–594. https://doi.org/10.1007/s10753-019-01139-2
  • Arshad Zahoor, Chao Yang, Yaping Yang, Muhammad Akhtar, Talha Umar, Murad Ali Khan, Shakoor Ahmad, Ganzhen Deng, Meng-yao Guo. (2020). MerTK negatively regulates Staphylococcus aureus induced inflammatory response via SOCS1/SOCS3 and Mal. Immunobiology. https://doi.org/10.1016/j.imbio.2020.151960
  • Shaukat, A., Yang, C., Yang, Y., Guo, Y. F., Jiang, K., Guo, S., Liu, J., Zhang, T., Zhao, G., Ma, X., Wu, Z., Zhou, Q., Akhtar, M., Zahoor, A., Umar, T., Shaukat, I., Hanif, S., Rajput, S. A., Hassan, M., Mehmood, K., … Deng, G. (2020). Ginsenoside Rb 1: A novel therapeutic agent in Staphylococcus aureus-induced Acute Lung Injury with special reference to Oxidative stress and Apoptosis. Microbial pathogenesis, 143, 104109. https://doi.org/10.1016/j.micpath.2020.104109
  • Akhtar, M., Guo, S., Guo, Y. F., Zahoor, A., Shaukat, A., Chen, Y., Umar, T., Deng, P. G., & Guo, M. (2020). Upregulated-gene expression of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6) via TLRs following NF-κB and MAPKs in bovine mastitis. Acta tropica, 207, 105458. https://doi.org/10.1016/j.actatropica.2020.105458
  • Zaima Umar, Anas Sarwar Qureshi, Muhammad Usman, Adeel Sarfraz, Talha Umar, Mumtaz Hussain and Saqib Umar. (2018). Response of dietary supplementation of black seed (Nigella sativa) oil on hematological parameters, serum biochemistry and reproductive hormones in male rabbits. Academia Journal of Medicinal Plants 6(9): 276-280. DOI: 10.15413/ajmp.2018.0149
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