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Dr. Sarah Rajabi, Ph.D.

Associate Professor

Mar 2022 - Present

Royan Institute for Stem Cell Biology and Technology

Tehran

Islamic Republic of Iran

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Dr. Sarah Rajabi received her M.Sc. and Ph.D. degrees in Cellular and Developmental Biology from Kharazmi University, Tehran, Iran, in 2008 and 2013, respectively. In 2009, she joined the prestigious Royan Institute, where she completed a postdoctoral research fellowship in heart bioengineering under the supervision of Prof. Hossein Baharvand in 2017.

Dr. Rajabi's research focuses on the design and fabrication of extracellular matrix (ECM)-derived biomaterials and the exploration of stem cell interactions with various scaffolds for applications in cardiovascular, skin, and muscle tissue engineering. Her innovative work bridges biomaterials science and regenerative medicine, addressing critical challenges in tissue engineering.

She has published over 45 scientific articles in high-impact journals and serves on the Editorial Boards of MedLiber of Regenerative Medicine and Bioengineering and Technology. Dr. Rajabi's dedication to advancing regenerative medicine is also reflected in her leadership as a full member of Sigma Xi, The Scientific Research Honor Society, and her active involvement in several national and international research collaborations.

Currently, Dr. Rajabi holds the position of Associate Professor in the Cell Engineering Department at the Royan Institute for Stem Cell Biology and Technology. In this role, she not only continues her pioneering research but also mentors the next generation of scientists.

Among her many accolades, Dr. Rajabi is recognized for her work in heart bioengineering, specifically for her achievement in producing a miniaturized artificial human heart in a bioreactor system, which earned her the title of Researcher of the Year at the Royan International Congress on Stem Cells in 2019.

Her contributions to the field extend beyond research to include organizing and leading specialized workshops in tissue engineering, mentoring over 30 graduate students, and authoring multiple book chapters. Dr. Rajabi's commitment to innovation, combined with her collaborative and multidisciplinary approach, positions her as a leading figure in the advancement of regenerative medicine and tissue engineering.

  • Stem Cell Biology
  • Tissue Engineering
  • Biomaterials
  • Bioengineering
  • Regenerative Medicine
  • Stem Cell Therapy
  • Design and Production of Different Decellularized Tissues
  • ECM-Based Hydrogels
  • 3D Sponge Scaffolds Fabrication for Wound Dressing
  • Skeletal Muscle Regeneration
  • Cardiovascular Tissue Engineering
  • Biomedical Engineering Field
  • Functional Efficacy of Tissue-Engineered Small-Diameter Nanofibrous Polyurethane Vascular Grafts Surface-Modified by Methacrylated Sulfated Alginate in the Rat Abdominal Aorta. Amiri Heydari H, M, Mostafaei F, Alipour Choshali M, Shiravandi A, Rajabi S, Daemi.H. ACS Applied Materials & Interfaces. 2024. Q1, IF: 9.5, Citation: 0
  • Efficacy of 3D-printed chitosan cerium oxide dressings coated with vancomycin-loaded alginate for chronic wounds management. Shahroudi Sh, Parvinnasab A, Salahinejad E, Abdi Sh, Rajabi S,Tayebi L. Carbohydrate Polymers. 2024. Q1, IF: 10.7, Citation: 0
  • Surface Modification of Dentin Powder With Alginate and Evaluation of Its Effects on the Viability and Proliferation of Dental Pulp Stem Cells (In Vitro) and its Biocompatibility. Manzarpour M, Mousavi MR, Mahdavinaderi Y, Najimi M, Ghalambor A, Hasannia S, Rajabi S, Pezeshki-Modaress M, Kamali A, Bakhtiar H. Journal of Endodontics. 2024. Q1, IF: 5.4, Citation: 0
  • Folic acid-modified nanocrystalline cellulose for enhanced delivery and anti-cancer effects of crocin. Soltani M, Farhadi A, Rajabi S, Homayouni‐Tabrizi M, Sameer Hussein F & Mohammadian N. Scientific Report. 2024. Q1, IF: 3.8, Citation: 1
  • Promotion of Cardiac Microtissue Assembly within G-CSF-enriched Collagen I-Cardiogel Hybrid Hydrogel. Khodayari H, Khodayari S, Rezaee M, Siamak Rezaeiani, Alipour Choshali M, Erfanian S, Muhammadnejad A, Nili F, Pourmehran Y, Pirjani R, Rajabi S, Aghdami N, Nebigil-désaubry C, Wang K, Mahmoodzadeh H, Pahlavan S. (2024). Regenerative Biomaterials. 2024. Q2, IF: 5.7. Citation: 0
  • Electroconductive Nanofiber/Myocardium Gel Scaffolds Applicable for Myocardial Infarction Therapy. Fakhrali A, Tamimi M, Semnani D, Salehi H, Ghodsi A, Rajabi S, Pezeshki-Modaress M, Ebadi SV, Abdi SH, Ghane M. ACS Applied Polymer Materials. 2024. Q1, IF: 4.5, Citation: 1
  • Progression Course in the Birth Parturition of Waste Materials Toward Application in Tissue Engineering-Based Approaches. Tamimi M, Abdi SH, Erfanian S, Nekouifar E, Soltani M, Hosseinzade D, Rajabi S. MedLiber Regener. Med. 2024. IF: 0, Citation: 0
  • Cell Immortality: In Vitro Effective Techniques to Achieve and Investigate Its Applications and Challenges . Chalak M, Hesaraki M, Mirbahari SN, Yeganeh M, Abdi SH, Rajabi S, Hemmatzadeh F. life. 2024. Q2, IF: 3.2. Citation: 9. (International collaboration with the University of Adelaide).
  • Fabrication and characterization of a novel injectable human amniotic membrane hydrogel for dentin-pulp complex regeneration. Bakhtiar H, Mousavi MR, Rajabi S, Pezeshki-Modaress M, Ayati A, Ashoori A, Ellini MR, Baaji KH, Kamali A, Abediasl ZH, Azarpazhooh A, Kishen A. Dental Materials. 2023. Q1, IF: 4.6 Citation: 10
  • Decellularized lung extracellular matrix scaffold promotes human embryonic stem cell differentiation towards alveolar progenitors. Noori A, Mokhber Dezfouli MR, Rajabi S, Ganji F, Ghezelayagh Z, El Agha E, Baharvand H, Sadeghian Chaleshtori S, Tahamtani Y. Cell Journal (Yakhteh). 2023. Q3, IF: 2.5, Citation: 7
  • Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study. Ebadi M, Miresmaeili A, Shojaei S, Farhadi S, Rajabi S. Biological Procedures Online. 2023. Q1, IF: 7.2. Citation: 5
  • 5-Azacytidine incorporated skeletal muscle-derived hydrogel promotes rat skeletal muscle regeneration. Mirza Ahmadi B, Noori A, Kazemi Ashtiani M, Rajabi S, Talkhabi M. Cells & Development. 2023. Q2, IF:2.1, Citation: 7
  • Hybrid gelatin-sulfated alginate scaffolds as dermal substitutes can dramatically accelerate the healing full-thickness diabetic wounds. Sadeghi A, Zare-Gachi M, Najjar-Asl M, Rajabi S, Fatemi M, Farokh Forghani S, Daemi H, Pezeshki-Modaress M. Carbohydrate Polymers. 2023. Q1, IF: 10.5, Citation: 23
  • Three-dimensional biomimetic reinforced chitosan/gelatin composite scaffolds containing PLA nano/microfibers for soft tissue engineering application . Eftekhari-Pournigjeh F, Saeed M, Rajabi S, Tamimi M, Pezeshki-Modaress M. International Journal of Biological Macromolecules. 2023. Q1, IF: 7.7, Citation: 12
  • An aorta ECM extracted hydrogel as a biomaterial in vascular tissue engineering application. Baaji K, Pezeshki-Modaress M, Rajabi S. Progress in Biomaterials. 2022. Q1, IF: 4.87. Citation: 0
  • SDF-1α loaded bioengineered human amniotic membrane-derived scaffold transplantation in combination with hyperbaric oxygen improved diabetic wound healing. Nasiry D, Khalatbary A, Abdollahifar M, Bayat M, Amini A, Kazemi Ashtiani M, Rajabi S, Noori A, Piryaei A. Journal of Bioscience and Bioengineering. 2022. Q3, IF: 2.3, Citation: 36
  • Human amniotic membrane extracellular matrix scaffold for dental pulp regeneration in vitro and in vivo. Bakhtiar H, Ashoori A, Rajabi S, Pezeshki‐Modaress M, Ayati A, Mousavi MR, Ellini MR, Kamali A, Azarpazhooh A, Kishen A. International Endodontic Journal. 2022. Q1, IF: 5.4 Citation: 23 (International collaboration with the University of Toronto).
  • Shape memory injectable cryogel based on carboxymethyl chitosan/gelatin for minimally invasive tissue engineering: In vitro and in vivo assays. Bagheri‐Khoulenjani S, Olov N, Mirzadeh H, Moradi R, Rajabi S. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2022. Q2, IF: 3.2, Citation: 11
  • Fabrication and In Vitro Evaluation of A Chondroitin Sulphate-Polycaprolactone Composite Nanofibrous Scaffold for Potential Use in Dermal Tissue Engineering. Pezeshki-Modaress M, Akbarzadeh M, Ebrahimibagha D, Zandi M, Ghadimi T, Sadeghi A, Rajabi S. Cell Journal. 2022. Q3, IF: 3.12. Citation: 2
  • Heart Repair Induced by Cardiac Progenitor Cell Delivery within Polypyrrole-Loaded Cardiogel Post-ischemia. Parchehbaf-Kashani M, Ansari H, Mahmoudi E, Barekat M, Sepantafar M, Rajabi S, Pahlavan S. ACS Applied Bio Materials. 2021. Q1, IF: 4.7. Citation: 20
  • Oxygen-rich Environment Ameliorates Cell Therapy Outcomes of Cardiac Progenitor Cells for Myocardial Infarction.Montazeri L, Kowsari-Esfahan R, Pahlavan S, Sobat M, Rabbani S, Ansari H, Varzideh F, Barakat M, Rajabi S, Navaee F, Bonakdar S, Renaud P, Braun T, Baharvand H. Materials Science and Engineering: C. 2021. Q1, IF: 8.45. Citation: 1 (International collaboration with the Max Planck Institute for Heart and Lung Research and the University of Lausanne)
  • Highly tough and ultrafast self-healable dual, crosslinked sulfated alginate-based polyurethane elastomers for engineering vascular tissue. Mostafavi A, Daemi H, Rajabi S, Baharvand H. Carbohydrate Polymers. 2021. Q1, IF: 10.7. Citation: 35
  • Bioinspired Device Improves the Cardiogenic Potential of Cardiac Progenitor Cells. Shams Z, Akbari B, Rajabi S, Aghdami N. Cell Journal. 2021. IF: 3.12, Citation: 1
  • A simple, green chemistry technology for the fabrication of tissue-engineered scaffolds based on mussel-inspired 3D centrifugal spun. Saeed M, Beigi-Boroujeni S, Rajabi S, Rafati Ashteiani G, Dolatfarahi M, Özcan M. Materials Science and Engineering: C. 2021. Q1, IF: 8.45, Citation: 14
  • Optimizing methods for bovine dental pulp decellularization. .Bakhtiar H, Rajabi S, Pezeshki-Modaress M, Ellini MR, Panahinia M, Alijani S, Mazidi A, Kamali A, Azarpazhooh A, Kishen A. Journal of Endodontics. 2021. Q1, IF: 5.16, Citation: 38 (International collaboration with the University of Toronto).
  • Cardiac ECM/chitosan/alginate ternary scaffolds for cardiac tissue engineering application. Tamimi M, Rajabi S, Pezeshki-Modarres M. International Journal of Biological Macromolecules. 2021. Q1, IF:8, Citation: 81
  • Decellularized muscle‐derived hydrogels support in vitro cardiac microtissue fabrication. Rajabi S, Aghdami N, Varzideh F, Parchehbaf‐Kashani M, Nobakht Lahrood F. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2020. Q2, IF: 3.4, Citation: 10
  • Design and characterization of an electroconductive scaffold for cardiomyocytes-based biomedical assays. Parchehbaf-Kashani M, Sepantafar M, Talkhabi M, Sayahpour F, Baharvand H, Pahlavan S, Rajabi S. Materials Science & Engineering C. 2020. Q1, IF: 8.45. Citation: 37
  • Pulp ECM-derived macroporous scaffolds for stimulation of the dental-pulp regeneration process. Bakhtiar H, Pezeshki-Modaress M, Kiaipour Z, Shafiee M, Ellini MR, Mazidi A, Rajabi S, Zamanlui Benisi S, Ostad S, Galler K, Pakshir P, Azarpazhooh A, Kishen A. Dental Materials. 2020. Q1, IF: 2.4, Citation: 51 (International collaboration with the University of Toronto).
  • Vascular endothelial growth factor sustained delivery augmented cell therapy outcomes of cardiac progenitor cells for myocardial infarction. Montazeri L, Sobat M, Kowsari-Esfahan R, Rabbani S, Ansari H, Barakat M, Firoozi S, Rajabi S, Vahdat S, Baharvand H, Pahlavan S. Journal of Tissue Engineering and Regenerative Medicine. 2020. Q2, IF: 4.32, Citation: 3
  • Assessment of the Efficacy of Tributylammonium Alginate Surface-Modified Polyurethane as an Antibacterial Elastomeric Wound Dressing for both Non-Infected and Infected Full-Thickness Wounds. Hosseini Salekdeh S, Daemi H, Zare-Gachi M, Rajabi S, Bazgir F, Aghdami N, Nourbakhsh M, and Baharvand H. ACS Applied Materials & Interfaces. 2019. Q1, IF:10.38. Citation: 44
  • Tough, hybrid chondroitin sulfate nanofibers as a promising scaffold for skin tissue engineering. Sadeghi A, Zandi M, Pezeshki-Modaress M, Rajabi S. International journal of biological macromolecules. 2019. Q1, IF:8.025, Citation: 58
  • Optimization of miRNA delivery by using a polymeric conjugate based on deoxycholic acid-modified polyethyleneimine. Radmanesh f, Sadeghi Abandansari h, Pahlavan S, Alikhani M, Karimi M, Rajabi S, Kazemi B, Baharvand H. International Journal of Pharmaceutics. 2019. Q1, IF: 6.5, Citation: 10
  • Cardioprotective effects of omega‐3 fatty acids and ascorbic acid improve the regenerative capacity of embryonic stem cell‐derived cardiac lineage cells. Shabani P, Ghazizadeh Z, Gorgani‐Firuzjaee S, Molazem M, Rajabi S, Vahdat S, Azizi Y, Doosti M, Aghdami N, Baharvand H. BioFactors. 2019. Q1, IF: 6.43, Citation: 15
  • Exosomes Secreted by Normoxic and Hypoxic Cardiosphere-derived Cells Have Anti-Apoptotic Effect. Namazi H, Namazi I, Ghiasi P, Ansaric H, Rajabi S, HajizadehSaffar E, N, Aghdami N and Mohit E. Iranian Journal of Pharmaceutical Research. 2018. Q2, IF: 1.8, Citation: 26
  • Exosomes secreted by hypoxic cardiosphere‐derived cells enhance tube formation and increase pro‐angiogenic miRNA. Namazi H, Mohit E, Namazi I, Rajabi S, Samadian A, Hajizadeh‐Saffar E, Aghdami N, Baharvand H. Journal of cellular biochemistry. 2018. Q3, IF: 4.48, Citation: 95
  • Tailoring the gelatin/chitosan electrospun scaffold for application in skin tissue engineering: an in vitro study. Pezeshki-Modaress M, Zandi M, Rajabi S. Progress in biomaterials. 2018. Q1, IF: 4.87, Citation: 102
  • In situ formation of interpenetrating polymer network using sequential thermal and click crosslinking for enhanced retention of transplanted cells. Sadeghi Abandansari H, Ghanian M, Varzideh F, Mahmoudi E, Rajabi S, Taheri P, Nabid MR, Baharvand H. Biomaterials. 2018. Q1, IF: 12.8, Citation: 72
  • Human embryonic stem cell-derived cardiovascular progenitor cells efficiently colonize in the bFGF-tethered natural matrix to construct contracting humanized rat hearts. Rajabi S, Pahlavan S, Ansari H, Abbasalizadeh S, Kazemi Ashtiani M, Sayyahpour F, Varzideh F, Ossia S, Kostin S, Braun T, Aghdami N, Baharvand H. Biomaterials. 2018. Q1, IF: 12.8, Citation: 48 (International collaboration with the Max Planck Institute for Heart and Lung Research, Germany).
  • Effect of chemical immobilization of SDF-1α into muscle-derived scaffolds on angiogenesis and muscle progenitors recruitment. Rajabi S, Jalili-Firoozinezhad S, Kazemi Ashtiani M, Tajbakhsh S, Baharvand H. J Tissue Eng Regen Med. 2017. Q2, IF: 4.323, Citation: 28 (International collaboration with Institute Pasteur, France).
  • Fabrication and characterization of heparin/collagen sponge for in vitro differentiation of Wharton’s jelly-derived mesenchymal stem cells into hepatocytes. Aleahmad F, Talaei-Khozani T, Rajabi-Zeleti S, Sani M, Jalili-Firoozinezhad S, Bonakdar S, Heshmat-Azad S, Azaria M, Jaberipour M. (2017). Hepat. Mont.Journa. IF:1.214, Citation: 6
  • Mechanical reinforcement of urinary bladder matrix by electrospun polycaprolactone nanofibers. Ghafaria,AM, Rajabi-Zeleti S, Naji M, Ghanian M and Baharvand H. Sceintica Iranica Journal. 2017. Q3, IF: 1.4Citation: 6
  • Gelatin/chondroitin sulfate nanofibrous scaffolds for stimulation of wound healing: In-vitro and in-vivo study. Pezeshki-Modaress M, Mirzadeh H, Zandi M, Rajabi-Zeleti S, Sodeifi N, Aghdami N, K. Mofrad MR. Journal of Biomedical Materials Research. 2017. Q4, IF: 3.9, Citation: 63 (International collaboration with University of California, USA)
  • Electrically conductive gold nanoparticle-chitosan thermosensitive hydrogels for cardiac tissue engineering. Baei P, Jalili-Firoozinezhad S, Rajabi-Zeleti S, Tafazzoli-Shadpour M, Baharvand H, Aghdami N. Materials Science and Engineering: C. 2016. Q1, IF: 8.45, Citation: 346
  • Influence of decellularized pericardium matrix on the behavior of cardiac progenitors. Jalili‐Firoozinezhad S, Rajabi‐Zeleti S, Marsano A, Aghdami N, Baharvand H. Journal of Applied Polymer Science. 2016. Q2, IF: 3.05. Citation: 11
  • Stem Cells and Injectable Hydrogels: Synergistic Therapeutics in Myocardial Repair. Sepantafar M, Maheronnaghsh R, Mohammadi H, Rajabi-Zeleti S, Aghdami N, Baharvand H. Biotechnology Advances. 2016. Q1, IF: 12.1, Citation: 138
  • A robust super-tough biodegradable elastomer engineered by supramolecular ionic interactions. Daemi H, Rajabi-Zeleti S, Sardon H, Barikani M, khademhosseini A, Baharvand H. Biomaterials. 2016. Q1, IF: 12.5, Citation: 107
  • Preparation of biodegradable gelatin/PVA porous scaffolds for skin regeneration. Mahnama H, Dadbin S, Frounchi M, and Rajabi S. Artif Cells Nanomed Biotechnol. 2016. Q1, IF:4.5, Citation: 77
  • Facile Fabrication of Egg White Macroporous Sponges for Tissue Regeneration. Jalili-Firoozinezhad S, Rajabi-Zeleti S, Mohammadi P, Gaudiello E, Bonakdar S, Solati-Hashjin M, Marsano A, Aghdami N, Scherberich A, Martin I and Baharvand H. Advanced Healthcare Materials. 2015. Q1, IF: 10, Citation: 54 (International collaboration with Departments of Biomedicine and of Surgery, University Hospital Basel, University of Basel, Switzerland)
  • Chitosan-gelatin sheets as scaffolds for muscle tissue engineering. Hajiabbas M, Mashayekhan S, Nazaripouya A, Naji M, Hunkeler D, Rajabi Zeleti S, Sharifi Aghdas F. Artificial Cells, Nanomedicine, and Biotechnology. 2015. Q1, IF: 4.5, Citation: 36 (collaboration with AquaTECH, CH-1237 Avully, Geneva, Switzerland)
  • The behavior of cardiac progenitor cells on macroporous pericardium-derived scaffolds. Rajabi-Zeleti S, Jalili-Firoozinezhad S, Azaria M, Khayyatan F, Vahdat S, Nikeghbalian S, Khademhosseini A, Baharvand H, Aghdami N. Biomaterials. 2014. Q1, IF: 12.5, Citation: 131
  • Comparing Supportive Properties of Poly-Lactic-Co-Glycolic Acid (PLGA), PLGA/Collagen and Human Amniotic Membrane for Human Urothelial and Smooth Muscle Cells Engineering. Sharifiaghdas F, Naji M, Sarhangnejad R, Rajabi-Zeleti S, Mirzadeh H, Zandi M, Saeed M. Urology Journal. 2014. IF: 1.5, Citation: 19
  • Cell‐loaded gelatin/chitosan scaffolds fabricated by salt‐leaching/lyophilization for skin tissue engineering: In vitro and in vivo studyPezeshki‐Modaress M, Rajabi‐Zeleti S, Zandi M, Mirzadeh H, Sodeifi N, Nekookar A, Aghdami N. J Biomed Mater Res Part A. 2014. Q2, IF: 3.9, Citation: 79
  • Functionalization and surface modification of electrospun polylactic acid scaffold for tissue engineering. Hoveizi E, Nabiuni M, Parivar K, Rajabi‐Zeleti S, Tavakol S. Cell Biol Int. 2013. Q3, IF: 3.3, Citation: 101
  • Human Embryology and Developmental Biology. By: Bruce M. Carlson. Translated to Farsi. 2013
  • Natural and Synthetic Hydrogels, Editor: Ravin Narian (University of Alberta). (Three Chapters, Chapter 12. Extracellular Matrix (ECM) based Hydrogels, Chapter 25. Hydrogels for Wound Dressing and Chapter 20. Hydrogels in Cell and Tissue Engineering). Elsevier publication. 2024.
  • Cell Therapy and Regenerative Medicine 1 (from a stem cell and regenerative medicine book collection). Editors: Hossein Baharvand and Dr. Ensiyeh Hajizadeh Saffar. Chapter Two (Industrial production of cells). Royan Institute. 2020
  • Tissue Engineering (Stem Cells and Regenerative Medicine Book Series). Editors: Hossein Baharvand and Dr. Mohamamd Kazemi Ashtiani, Chapter 10 (Nanotechnology application in Tissue Engineering) Royan Institute. 2020.