Jianfei Fu

Chief Physician, Associate Professor, Hematology

Tongji Hospital affiliated to Tongji University

389 Xincun Road

Shanghai, China

fjf2017@tongji.edu.cn

Education

July 2007 - MD, Ph.D. in Internal Medicine(hematology), Shanghai Jiao Tong University, Shanghai, China

July 1997 - M.S. in Internal Medicine(hematology), Southeast University, Nanjing, China

July 1994 - B.S.  in Clinical Medicine, Southeast University, Nanjing, China

Experience

2022-Present - Chief Physician, Associate Professor, Tongji Hospital Affiliated to Tongji University, Shanghai, China

2009-2021 - Deputy Chief Physician, Associate Professor, Tongji Hospital Affiliated to Tongji University, Shanghai, China

2007-2008 - Attending Physician, Lecturer, Tongji Hospital Affiliated to Tongji University, Shanghai, China

2000-2004 - Attending Physician, Lecturer, Tongji Hospital Affiliated to Tongji University, Shanghai, China

1997-2000 - Resident Physician, Assistant, Tongji Hospital Affiliated to Tongji University, Shanghai, China

• Hematology
• Immune cells
• Acute Myeloid Leukemia
• DNA
• RNA and mRNA
• Genetics
• Stem Cells

• Zhou J, Wu H, Zhu Shunli, Liang AB, Fu JF. CD69 predicts prognosis through immune cell infiltration and Decitabine treatment response in Acute Myeloid Leukemia. Translational Cancer Research (2025 accepted).
• Zhou J, Wu H, Liang AB, Fu JF. Single nucleotide polymorphism and promoter methylation analysis of protein tyrosine phosphatase 1B in patients with myeloproliferative neoplasms. Translational Cancer Research (Published online Jan 23, 2025).
• Liu Y, Xiao G, Liu Y, Tu S, Xue B, Zhong Y, Zhang C, Zhou L, Ye S, Lu Y, Xiu B, Zhang W, Ding Y, Fu J, Li P, Huang L, Luo X, Liang A. CAR T-cell therapy combined with autologous hematopoietic cell transplantation in patients with refractory/relapsed Burkitt Lymphoma. Curr Res Transl Med. 2024 Oct 23;73(1):103477.
• Zhu J, Zhu X, Xie F, Ding Y, Lu H, Dong Y, Li P, Fu J, Liang A, Zeng Y, Xiu B. Case report: Circulating tumor DNA technology displays temporal and spatial heterogeneity in Waldenström macroglobulinemia during treatment with BTK inhibitors. Pathol Oncol Res. 2023 Apr 19;29:1611070.
• Araki D, Fu JF, Huntsman H, Cordes S, Seifuddin F, Alvarado LJ, Cheruku PS, Cash A, Traba J, Li Y, Pirooznia M, Smith RH, Larochelle A. NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia. Stem Cell Reports. 2021;16(9):2336-2350.
• Zhou J, Wu H, Guo C, Li B, Zhou LL, Liang AB, Fu JF. A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms. Bioengineered. 2021;12(2):10564-10586.
• Zhou J, Guo C, Wu H, Li B, Zhou LL, Liang AB, Fu JF. Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells. BMC Cancer. 2021;21(1):1213.
• Yang BQ, Zhang ZK, Wu H, Chen YH, Liang AB, Fu JF. [Relationship between clinical features and mutations of MDS-related genes in patients with myelodysplastic syndrome]. Journal of Tongji University (Medical Science). 2021;42(3):361-366, 374. Chinese
• Ding Y, Dong Y, Lu H, Luo X, Fu J, Xiu B, Liang A, Zhang W. Circular RNA profile of acute myeloid leukaemia indicates circular RNA annexin A2 as a potential biomarker and therapeutic target for acute myeloid leukaemia. Am J Transl Res. 2020 May 15;12(5):1683-1699.
• Lu J, Wu Y, Li B, Luo X, Zhang W, Zeng Y, Fu J, Liang A, Xiu B. Predictive value of serological factors, maximal standardized uptake value and ratio of Ki67 in patients diagnosed with non-Hodgkin's lymphoma. Oncol Lett. 2020 Oct;20(4):47.
• XY Zheng, AB Liang, XZ Yang, JF Fu, M Hou, AN Sun, H Lu, J Jin, JD Hu. [Pharmacokinetic study of domestic caspofungin compared with original caspofungin for empirical therapy in patients with persistent fever and agranulocytosis]. Zhonghua Xue Ye Xue Za Zhi. 2020 Dec 14;41(12):1031-1034. Chinese.
• Zhou J, Wu H, Li B, Liang AB, Fu JF. [Detection of Genetic Mutations in Primary Hypereosinophilia Patients]. Chinese Journal of Experimental Hematology. 2019;27(2):504-508. Chinese
• Huntsman HD, Bat T, Cheng H, Cash A, Cheruku PS, Fu JF, Keyvanfar K, Childs RW, Dunbar CE, Larochelle A. Human hematopoietic stem cells from mobilized peripheral blood can be purified based on CD49f integrin expression. Blood. 2015 Sep 24; 126(13): 1631-3.
• Ding Y, Li P, Zhang W, Wu H, Chen Y, Xiu B, Lu H, Li B, Fu J, Bo L, Liang A. [Treatment of Ph-adult acute lymphoblastic leukemia patients with Tongji-96 regimen]. Zhonghua Xue Ye Xue Za Zhi. 2015 Apr;36(4):272-6. Chinese.
• Zhang W, Ding Y, Wu H, Chen Y, Lu H, Chen C, Fu J, Wang W, Liang A, Zou S. Retrospective comparison of fludarabine in combination with intermediate-dose cytarabine versus high-dose cytarabine as consolidation therapies for acute myeloid leukemia. Medicine (Baltimore). 2014 Dec;93(27):e134.
• Xiu B, Zhang W, Huang B, Chen J, Lu H, Fu J, Xiong H, Liang A. Genetic inhibition of vascular endothelial growth factor receptor-1 significantly inhibits the migration and proliferation of leukemia cells and increases their sensitivity to chemotherapy. Oncol Rep. 2013 May;29(5):2030-8.
• Liang A, Zhang H, Fang Y, Li Y, Zhu D, Chen F, Lu H, Fu J, Bo L. Sequential arabinosylcytosin with or without fludarabine in paracmastic patients with acute myeloid leukemia. Pharmazie. 2012 Jul;67(7):635-8.18.
• Xiong H, Liang AB, Xiu B, Fu JF, Ding Y, Chen YH. N-Propionyl polysialic acid precursor enhances the susceptibility of multiple myeloma to antitumor effect of anti-NprPSA monoclonal antibody. Acta Pharmacol Sin. 2012 Dec;33(12):1557-62.
• Qin W, Li LL, Lu HN, Huang BB, Xiu B, Bo LJ, Gao QM, Zhang WJ, Fu JF.[Study of hypermethylation of SOCS gene in typical myeloproliferative disease]. Zhonghua Xue Ye Xue Za Zhi. 2011 Nov;32(11):772-6. Chinese
• Qin W, Fu JF. [Research advances on relationship between suppressor of cytokine signaling 3 and myeloproliferative neoplasms]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Aug;18(4):1101-4. Chinese.
• Fu JF, Bo LJ, Xiong H, [Research on MPL Gene Mutations in Patients with Chronic Myeloproliferative Neoplasms.] Zhonghua Xue Ye Xue Za Zhi, 2009, 30(9):634-637 Chinese
• CHEN Jing-de, HAN Ying, HUANG Bin-bin, BO Lan-jun, FU Jian-fei, XIONG Hong, LIANG Ai-bin. [Experimental study of apoptosis in leukemic cell lines induced by combined use of Bevacizumab and chemotherapeutic drug]. Journal of Leukemia & Lymphoma, 2009, 18(02)：75-78. Chinese.
• Fu JF, Shi JY, Zhao WL, Li G, Pan Q, Li JM, Hu J, Shen ZX, Jin J, Chen FY, Chen SJ. MassARRAY assay: a more accurate method for JAK2V617F mutation detection in Chinese patients with myeloproliferative disorders. Leukemia. 2008;22:660-663.
• Wang LN, Pan Q, Fu JF, Shi JY, Jin J, Li JM, Hu J, Zhao WL, Chen Z, Chen SJ. FIP1L1-PDGFR alone or with other genetic abnormalities reveals disease progression in hypereosinophilic syndrome but good response to imatinib. Chinese Medical Journal. 2008;121(10):867-873.
• Zhu YM, Zhao WL, Fu JF, Shi JY, Pan Q, Hu J, Gao XD, Chen B, Li JM, Xiong SM, Gu LJ, Tang JY, Liang H, Jiang H, Xue YQ, Shen ZX, Chen Z, Chen SJ. NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis. Clin Cancer Res. 12(10):3043-9. 2006.

• 2023 - [Structured Disease-Specific Dataset for Clinical Research---Myelodysplastic Syndrome] (in chinese).
• 2023 - [Structured Disease-Specific Dataset for Clinical Research---Leukemia] (in chinese).
• 2023 - [Guidelines for Integrated Diagnosis and Treatment of Cancer in China – Technical Volume] (in chinese).

• https://loop.frontiersin.org/people/2648788