WebLog Journal of Hematology

Monoclonal Gammopathy of Renal Significance (MGRS) is a clinical entity characterized by renal damage caused by monoclonal proteins secreted by clonal plasma or B-cell proliferative disorders, without meeting criteria for overt hematologic malignancies like multiple myeloma or lymphoma. From a hematologist's viewpoint, early identification of the underlying clone is crucial for guiding targeted therapy to preserve renal function.

MGRS lesions are classified into organized…

Cyanosis is most often due to cardiac or pulmonary disease, but genetic and acquired disorders of hemoglobin can result in significant arterial desaturation. Disorders such as methemoglobinemia, sulfhemoglobinemia, Hemoglobin M, Low oxygen affinity hemoglobin are the differential diagnosis once cardiopulmonary causes were excluded [1]. Acquired disorders are more common whereas long standing symptoms or symptoms in siblings is suggestive of hereditary causes. A 23-year-old female patient…

A spontaneous inferior epigastric artery rectus sheath hematoma is a rare condition where bleeding occurs within the sheath of the rectus abdominis muscle, often due to damage to the inferior epigastric artery or its branches. We present an adult case of giant spontaneous left inferior epigastric artery rectus sheath hematoma with dramatic life-threatening acute abdominal emergency which was managed successfully by conservative management.

Keywords: Acute Abdomen;…

In small ruminants, particularly goats and sheep, gastrointestinal (GI) parasites have led to serious socioeconomic and public health issues on a global scale. Goats and sheep can contract gastrointestinal parasites from helminths and protozoa, with nematodes and coccidian being the most prevalent. Parasite illnesses kill hundreds of thousands of livestock severely affecting the development of agriculture & poverty alleviation in emerging countries. Improving small ruminants’ health requires…

Pure Red Cell Aplasia (PRCA) is an infrequent hematological disorder marked by profound inhibition of erythroid production with preservation of other marrow cell lines. Its occurrence during the neonatal period is rare and often leads to delayed recognition. We describe a term neonate who presented with progressive pallor and severe anemia during the second week of life. Hematological evaluation revealed persistent normocytic normochromic anemia with marked reticulocytopenia. Bone marrow…

Inherited hematological disorders, to a degree, weapon cell affliction, thalassemia, and hemophilia, have long been a challenge in clinical care, accompanying restricted therapeutic alternatives. These disorders are caused by ancestral mutations that hinder the function of blood cells, leading to lifelong obstacles. Traditional situations, containing blood transfusions and bone marrow transplants, offer only temporary relaxation and are frequently associated with significant risks. Recent…