Congenital Neonatal Infected and Bleeding Hepatic Hamartoma Presenting as a Falciform Ligament Abscess, Successfully Treated by Emergency Left Hepatic Lobectomy, with Subsequent Development of Infantile Hemihypertrophy

Abstract

Mesenchymal Hamartoma of the Liver (MHL) is a rare benign hepatic pediatric tumor of infancy with approximately 20% of cases diagnosed during the neonatal period, typically presenting as an enlarging abdominal mass. Rare acute complications such as intralesional bleeding and infection can lead to rapid clinical deterioration. Neonatal presentation with infection, haemorrhage, and extension along the falciform ligament is exceptionally uncommon. We report a neonate who presented with sepsis and intralesional and falciform ligament bleeding due to an infected congenital hepatic hamartoma that tracked along the falciform ligament and mimicked a falciform ligament abscess. Emergency left hepatic lobectomy was lifesaving. During infancy, the child developed right‑sided hemihypertrophy, prompting tumor‑surveillance follow‑up. This case highlights the diagnostic complexity of neonatal hepatic masses, the importance of early surgical intervention, and the need for long‑term monitoring for overgrowth syndromes.

Keywords: Neonatal Hepatic Hamartoma; Mesenchymal Hamartoma of the Liver; Falciform Ligament Abscess; Neonatal Sepsis; Intraperitoneal Haemorrhage; Emergency Hepatic Lobectomy; Left Hepatic Lobectomy; Hepatic Resection; Congenital Liver Tumor; Hemihypertrophy; Hemihyperplasia; Overgrowth Syndromes; Pediatric Hepatobiliary Surgery; Neonatal Abdominal Mass

Citation

Govani DR, Mehta AR, Midha PK, Govani ND, Panchasara NG, Patel R, et al. Congenital Neonatal Infected and Bleeding Hepatic Hamartoma Presenting as a Falciform Ligament Abscess, Successfully Treated by Emergency Left Hepatic Lobectomy, with Subsequent Development of Infantile Hemihypertrophy. WebLog J Cancer Clin Res. wjcacr.2026.b1302. https://doi.org/10.5281/zenodo.18795347