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ARTICLE TYPE : CASE REPORT

Published on :   19 Feb 2026, Volume - 2
Journal Title :   WebLog Journal of Cerebrovascular Disease and Stroke | WebLog J Cerebrovasc Dis Stroke
Source URL:   weblog iconhttps://weblogoa.com/articles/wjcds.2026.b1902
Permanent Identifier (DOI) :  doi iconhttps://doi.org/10.5281/zenodo.18820190

Hypoxic-Ischemic Colitis at Griffiths’ Point in a Term Infant with Hypoxic-Ischemic Encephalopathy and Acute Kidney Injury Requiring Emergency Subtotal Colectomy

Govani DR 1
Swamy KB 2
Mehta AR 3
Midha PK 4
Govani ND 1
Panchasara NG 1
Patel RR 1
Patel RV 1 *
1Department of Pediatrics and Pediatric Surgery, Postgraduate Institute of Child Health & Research and KT Children Govt University Teaching Hospital, Rajkot, Gujarat, India
2Lincoln University College, 2, Jalan Stadium, SS7/15 SS7. 47301 Petaling Jaya, Selangor, Malaysia
3Formerly Head, Department of Surgery at Tata Memorial Hospital, Mumbai, India
4J. Watumull Global Hospital & Research Centre, Delwara Road, Mount Abu, Rajasthan, India

Abstract

A term male neonate with moderate Hypoxic-Ischaemic Encephalopathy (HIE) developed persistent rectal bleeding and rising inflammatory markers during therapeutic hypothermia. Despite conservative management, he deteriorated with signs of colonic ischaemia. Imaging suggested segmental hypoperfusion centred at Griffiths’ point at the splenic flexure, a recognised colonic watershed zone. Emergency laparotomy revealed extensive non-viable colon requiring subtotal colectomy with end ileostomy. Histopathology confirmed transmural ischaemic necrosis. This case highlights the vulnerability of neonatal colonic watershed regions to systemic hypoperfusion and underscores the need for early recognition of gastrointestinal complications in infants with HIE.

Keywords: Hypoxic-Ischaemic Colitis; Griffiths’ Point; Splenic Flexure Ischaemia; Neonatal Watershed Injury; Hypoxic-Ischaemic Encephalopathy (HIE); Acute Kidney Injury (AKI); T herapeutic Hypothermia; Rectal Bleeding in Neonates; Subtotal Colectomy; Neonatal Gastrointestinal Ischaemia; Transmural Colonic Necrosis; Mesenteric Hypoperfusion

Citation

Govani DR, Swamy KB, Mehta AR, Midha PK, Govani ND, Panchasara NG, et al. Hypoxic-Ischemic Colitis at Griffiths’ Point in a Term Infant with Hypoxic-Ischemic Encephalopathy and Acute Kidney Injury Requiring Emergency Subtotal Colectomy. WebLog J Cerebrovasc Dis Stroke. wjcds.2026.b1902. https://doi.org/10.5281/zenodo.18820190
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