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ARTICLE TYPE : CASE REPORT

Published on :   08 Jan 2026, Volume - 1
Journal Title :   WebLog Journal of Endocrinology and Diabetes | WebLog J Endocrinol Diabetes
Source URL:   weblog iconhttps://weblogoa.com/articles/wjed.2026.a0806
Permanent Identifier (DOI) :  doi iconhttps://doi.org/10.5281/zenodo.18222492

Hungry Bone Syndrome in the Postoperative Management of Primary Hyperparathyroidism: Report of Two Cases

Gorgi K 1 *
Chaouche M 2
1Department of Endocrinology and Metabolic Diseases, Ibn Sina University Hospital, Rabat, Morocco
2Department of Dermatology, Mohammed VI University Hospital, Agadir, Morocco

Abstract

Introduction: Hungry Bone Syndrome (HBS) is a rare but potentially severe metabolic complication following parathyroidectomy, occurring mainly in patients with severe primary hyperparathyroidism (PHPT) and high bone turnover [1–3].

Case Reports: We report two cases of HBS occurring after parathyroidectomy for advanced primary hyperparathyroidism. Both patients presented with marked preoperative hypercalcemia, very high parathyroid hormone (PTH) levels, and clinical and biological features of increased bone turnover. The postoperative course was characterized by prolonged hypocalcemia associated with hypophosphatemia, requiring intensive calcium and vitamin D supplementation.

Conclusion: HBS should be anticipated in high-risk patients undergoing parathyroidectomy. Early recognition and appropriate management are essential to reduce postoperative morbidity.

Keywords: Hungry Bone Syndrome; Primary Hyperparathyroidism; Parathyroidectomy; Postoperative Hypocalcemia

Citation

Gorgi K, Chaouche M. Hungry Bone Syndrome in the Postoperative Management of Primary Hyperparathyroidism: Report of Two Cases. WebLog J Endocrinol Diabetes. wjed.2026.a0806. https://doi.org/10.5281/zenodo.18222492
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