ARTICLE TYPE : RESEARCH ARTICLE
Published on : 10 Feb 2026, Volume - 2
Journal Title :
WebLog Journal of Endocrinology and Diabetes | WebLog J Endocrinol Diabetes
Source URL: 
https://weblogoa.com/articles/wjed.2026.b1001
Permanent Identifier (DOI) : 
https://doi.org/10.5281/zenodo.18790479
Vitamin D Status in Patients with Primary Hyperparathyroidism: Results from a Retrospective Study
2Dermatology Department, CHU Mohammed VI, Agadir, Morocco
3Endocrinology-Diabetology Department, Military Mohammed V Hospital, Rabat, Morocco
Abstract
Introduction: Primary Hyperparathyroidism (PHPT) is frequently associated with vitamin D deficiency, which may exacerbate hyperparathyroidism, hypercalcemia, and bone complications.
Objective: To assess vitamin D status in patients with PHPT and analyze its biological and clinical impact.
Patients and Methods: A retrospective study conducted over seven years (2015-2022) including patients hospitalized for PHPT. Serum 25-hydroxyvitamin D [25(OH)D] levels were systematically measured.
Results: Sixty-three patients were included (mean age: 55.8 years). The mean 25(OH)D level was 19.2 ng/mL. Vitamin D deficiency was observed in 60.3% of patients, insufficiency in 17.5%, and normal status in 22.2%. Patients with vitamin D deficiency had significantly higher serum calcium and Parathyroid Hormone (PTH) levels.
Conclusion: Vitamin D deficiency is highly prevalent among patients with PHPT and is associated with a more severe biological profile. Routine screening and correction of vitamin D deficiency should be integral to patient management.
Keywords: Primary Hyperparathyroidism; Vitamin D; PTH; Hypercalcemia; Bone Metabolism
Citation
Gorgi K, Chaouche M, Errahali Y, Rifai K, Iraqi H, Gharbi MH. Vitamin D Status in Patients with Primary Hyperparathyroidism: Results from a Retrospective Study. WebLog J Endocrinol Diabetes. wjed.2026.b1001. https://doi.org/10.5281/zenodo.18790479