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ARTICLE TYPE : CASE REPORT

Published on :   22 Dec 2025, Volume - 1
Journal Title :   WebLog Journal of Pediatrics | WebLog J Pediatr
Source URL:   weblog iconhttps://weblogoa.com/articles/wjp.2025.l2203
Permanent Identifier (DOI) :  doi iconhttps://doi.org/10.5281/zenodo.18058267

Infantile Acute Colonic Pseudo-Obstruction (Ogilvie’s Syndrome) Following Use of Dicyclomine in Infantile Colic- A Case Report

Govani DR 1
Swamy KB 2
Panchasara NG 1
Patel RR 1
Patel RV 1 *
1Department of Pediatrics and Pediatric Surgery, Postgraduate Institute of Child Health & Research and KT Children Govt. University Teaching Hospital, Rajkot 360001, Gujarat, India
2Director for International Affairs (South Asia), Lincoln University College (LUC), School of Medicine, 2, Jalan Stadium, SS7/15 SS7. 47301 Petaling Jaya, Selangor, Malaysia
3J. Watumull Global Hospital & Research Centre, Delwara Road, Mount Abu, Rajasthan 307501, India Affiliated to Medical Faculty of God Fatherly Spiritual University, Mount Abu, Rajasthan, India

Abstract

Infantile colic is a common functional gastrointestinal disorder characterized by excessive crying in otherwise healthy infants, Infantile colic is a common, self-limiting condition. Pharmacological interventions, particularly anticholinergic agents, have historically been attempted and used but are associated with significant risks and not recommended due to safety concerns. We report a 6-week old female infant who developed acute colonic pseudo-obstruction following administration of anticolic medication, dicyclomine, an atropine derivative prescribed for colic relief. Patient was successfully treated conservatively for a prolonged period and who subsequently developed congenital colorectal motility disorder on longer term follow up. This case underscores the dangers of anticholinergic therapy in infants and highlights the importance of non-pharmacological management strategies.

Keywords: Atropine Derivatives; Colonic Pseudo-Obstruction; Congenital Colorectal Motility Disorder; Dicyclomine; Gastrointestinal Functional Obstruction Disorder; Infantile Colic; Ogilvie’s Syndrome

Citation

Govani DR, Swamy KB, Midha PK, Govani ND, Panchasara NG, Patel RR, et al. Infantile Acute Colonic Pseudo Obstruction (Ogilvie’s Syndrome) Following Use of Dicyclomine in Infantile Colic- A Case Report. WebLog J Pediatr. wjp.2025.l2203. https://doi.org/10.5281/zenodo.18058267