Editor Profile

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Dr. Jaganmay Sarkar, Ph.D.

Scientist-STEM Cells-Integrated Drug Discovery

Jul 2022 - Present

Navi Mumbai

India

Yashraj Biotechnology

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I am Dr. Jaganmay Sarkar, did my Ph.D. in Biochemistry from the University of Kalyani, Kalyani, West Bengal, India. After completing my Ph.D., I was moved to the USA for my Postdoctoral research, and worked fortwo different institutes in the USA:Texas Tech University Health Science Center (TTUHSC), Amarillo, Texas, and alsothe University of Nebraska medical center (UNMC), Omaha, Nebraska.Before leaving for postdoctoral research I was working as a Biobank coordinator at Tata Translational Cancer Research Centre (TTCRC), Kolkata, India. During my research tenure, I was involved in innovative translational researchassociated with cardiovascular and lung diseases, pancreatic cancer tumor microenvironment, bone-related disorders, and stem cell-mediated therapies. I have published several articles and book chaptersin peer-reviewed international journals of global repute.I bring over 12 years of rich experience as a scientific researcher, bridging the realms of academia and industry. My journey has been defined by a hands-on commitment to advancing the field of Cell and Molecular biology within cutting-edge laboratory settings. I am passionate about pushing the boundaries of scientific exploration and dedicated to driving impactful results.

  • Cellular Signaling
  • Oncology Specially Tumor Microenvironment and Metastasis
  • Cardiovascular and Lung Diseases
  • Bone Microenvironment and Disorder
  • Stem Cell Differentiation to Different Lineages and Therapies
  • Sarkar J, Dhepe S, Shivalkar S, Kuhikar R, More S, Konala VBR, Bhanushali P, Khanna A (2023) Generation of Four Human Induced Pluripotent Stem Cell Lines Under Feeder-Free Culture Conditions from Peripheral Blood Mononuclear Cells of Indian Healthy Donors Using Integration-Free Sendai Virus Technology. Stem Cell Res. [IF: 1.2] (Under consideration)
  • Chitrangi S, Vaity P, Jamdar A, Sarkar J, Bhatt S (2023) Derivation of Breast Cancer Patient Derived Human Induced Pluripotent Stem Cell Line (YBLi006-A) with FANC-BRCA Gene Mutations: A Resource for Precision & Personalized Medicine. Stem Cell Res. doi: 10.1016/j.scr.2023.103128. [IF: 1.2]
  • Sarkar J, Das M, Howlader MSI, Prateeksha P, Barthels D, Das H (2022) Epigallocatechin-3- gallate inhibits osteoclastic differentiation and maturation by modulating mitophagy and mitochondrial functions. Cell Death Dis. 13:908. [IF: 9.685]
  • Laha D*, Sarkar J*, Maity J, Pramanik A, Das H (2022) Polyphenolic compounds inhibit osteoclast differentiation by reducing autophagy through limiting ROS and the mitochondrial membrane potential. Biomolecules.12:1220. [IF: 6.064] (*Contributed Equally)
  • Greene CJ, Anderson S, Barthels D, Howlader MSI, Kanji S, Sarkar J, Das H (2022) DPSC products accelerate wound healing in diabetic mice through induction of SMAD molecules. Cells. 11:2409. [IF: 7.666]
  • Maity J, Barthels D, Sarkar J, Prateeksha P, Deb M, Rolph D, Das H (2022) Ferutinin induces osteoblast differentiation of DPSCs via induction of KLF2 and autophagy/mitophagy. Cell Death Dis. 13:452. [IF: 9.685]
  • Sarkar J, Chakraborti T, Pramanik PK, Ghosh P, Mandal A, Chakraborti S (2021) PKCζ-NADPH Oxidase-PKCα Dependent Kv1.5 Phosphorylation by Endothelin-1 Modulates Nav1.5-NCX1-Cav1.2 Axis in Stimulating Ca2+ Level in Caveolae of Pulmonary Artery Smooth Muscle Cells. Cell Biochem Biophys. 79:57-71. [IF: 2.989]
  • Chowdhury A*, Sarkar J*, Pramanik PK, Chakraborti T, Chakraborti S (2020) Role of PKCζ-NADPH oxidase signaling axis in PKCα-mediated Giα2 phosphorylation for inhibition of adenylate cyclase activity by angiotensin II in pulmonary artery smooth muscle cells. Cell Biol Int. 44:1142-1155. [IF: 4.473] (*Contributed Equally)
  • Sarkar J, Chakraborti T, Chowdhury A, Bhuyan R, Chakraborti S (2019) Protective role of epigallocatechin-3-gallate in NADPH oxidase-MMP2-Spm-Cer-S1P signalling axis mediated ET-1 induced pulmonary artery smooth muscle cell proliferation. J Cell Commun Signal.13:473–489. [IF: 5.908]
  • Chakraborti S, Sarkar J, Chakraborti T (2019) Role of PLD-PKCζ signalling axis in p47phox phosphorylation for activation of NADPH oxidase by angiotensin II in pulmonary artery smooth muscle cells. Cell Biol Int. 43:678-694. [IF: 4.473]
  • Chakraborti S, Sarkar J, Bhuyan R, Chakraborti T (2018) Role of curcumin in PLD activation by Arf6- cytohesin1 signaling axis in U46619-stimulated pulmonary artery smooth muscle cells. Mol Cell Biochem. 438:97-109. [IF: 3.842]
  • Chakraborti S, Sarkar J, Bhuyan R, Chakraborti T (2018) Role of catechins on ET-1-induced stimulation of PLD and NADPH oxidase activities in pulmonary smooth muscle cells: determination of the probable mechanism by molecular docking studies. Biochem Cell Biol. 96:417-432. [IF: 3.626]
  • Chakraborti S, Sarkar J, Chowdhury A, Chakraborti T (2017) Role of ADP ribosylation factor6− Cytohesin1−PhospholipaseD signaling axis in U46619 induced activation of NADPH oxidase in pulmonary artery smooth muscle cell membrane. Arch Biochem Biophys. 633:1-14. [IF: 4.114]
  • Chowdhury A*, Nandy SK*, Sarkar J*, Chakraborti T, Chakraborti S (2017) Inhibition of pro-/active MMP-2 by green tea catechins and prediction of their interaction by molecular docking studies. Mol Cell Biochem. 427:111-122. [IF: 3.626] (*Contributed Equally)
  • Sarkar J, Nandy SK, Chowdhury A, Chakraborti T, Chakraborti S (2016) Inhibition of MMP-9 by green tea catechins and prediction of their interaction by molecular docking analysis. Biomed Pharmacother. 84:340-347. [IF: 7.419]
  • Sarkar J, Chowdhury A, Chakraborti T, Chakraborti S (2016) Cross-talk between NADPH oxidase- PKCα-p(38)MAPK and NF-κB-MT1MMP in activating proMMP-2 by ET-1 in pulmonary artery smooth muscle cells. Mol Cell Biochem. 415:13-28. [IF: 3.626]
  • Chowdhury A, Sarkar J, Pramanik PK, Chakraborti T, Chakraborti S (2016) Cross talk between MMP2-Spm-Cer-S1P and ERK1/2 in proliferation of pulmonary artery smooth muscle cells under angiotensin II stimulation. Arch Biochem Biophys. 603:91-101. [IF: 4.114]
  • Chowdhury A, Sarkar J, Chakraborti T, Chakraborti S (2015) Role of Spm-Cer-S1P signalling pathway in MMP-2 mediated U46619-induced proliferation of pulmonary artery smooth muscle cells: protective role of epigallocatechin-3-gallate. Cell Biochem Funct. 33:463-477. [IF: 3.963]
  • Shaikh S, Sarkar J, Pramanik A, Karmakar K, Chakraborti S (2013) Effect of m-calpain in PKCalpha- mediated proliferation of pulmonary artery smooth muscle cells by low dose of ouabain. Indian J BiochemBiophys. 50:419-427. [IF: 1.476]
  • Chowdhury A, Sarkar J, Chakraborti T, Pramanik PK, Chakraborti S (2016) Protective role of epigallocatechin-3-gallate in health and disease: A perspective. Biomed Pharmacother. 78:50-59. [IF: 7.419]
  • Chakraborti S, Chowdhury A, Alam MN, Sarkar J, Mandal A, Pramanik A, Chakraborti T (2014) Vascular aneurysms: A perspective. Indian J BiochemBiophys. 51: 449-456. [IF: 1.476]
  • Sarkar J, Konala VBR, and Das H (2023) Mechanisms of Bone Regeneration: Need More Critical Thinking. 'Regeneration and Mechanisms"-Springer Nature. (Manuscript submitted).
  • Sarkar J, Das H (2022) The role of endothelin axis and reactive oxygen species in future therapies of pancreatic cancer. Handbook of oxidative stress in cancer: Therapeutic aspects. Springer Nature Singapore. https://doi.org/10.1007/978-981-16-1247-3_272-1
  • Sarkar J, Chakraborti T, Chakraborti S (2019) Role of NADPH Oxidase-Induced Oxidative Stress in Matrix Metalloprotease-Mediated Lung Diseases. Oxidative Stress in Lung Diseases. Springer Nature Singapore.Vol 2, pp 75-101.
  • Chakraborti T*, Sarkar J*, Pramanik PK, Chakraborti S (2019) Environmental and Occupational agents and Cancer Drug-Induced Oxidative Stress in Pulmonary Fibrosis. Oxidative Stress in Lung Diseases. Springer Nature Singapore. Vol 2, pp 271-293. (*Contributed Equally)
  • Chakraborti S, Sarkar J, Pramanik PK, Chakraborti T (2017) Role of Proteases in Lung Disease: A Brief Overview. Proteases in Human Diseases. Springer, Singapore, pp 333-374.
  • Chakraborti S, Dey K, Alam MN, Mandal A, Sarkar J, Chakraborti T. (2016) Phospholemman: A Brief Overview. In Regulation of Membrane Na+-K+ ATPase. Springer International Publishing (pp. 243- 259).
  • Chakraborti S, Alam MN, Chowdhury A, Sarkar J, Pramanik A, Asrafuzzaman S, Das SK, Ghosh SN, Chakraborti T (2014) Pathophysiological aspects of lipoprotein associated phospholipase A2: A brief overview. Phospholipases in Health and Disease. Advances in Biochemistry in Health and Disease, Springer, New York pp115-131.
  • Shaikh S, Chowdhury A, Banerjee AK, Sarkar J, Chakraborti S (2013) Exercise and Matrix Metalloproteases in Health and Disease: A Brief Overview. Proteases in Health and Disease. Advances in Biochemistry in Health and Disease, Springer, New York, vol 7, pp 49-62.