Editor Profile
Dr. Jianjian Lin, Ph.D.
Clinical Research Coordinator
Jul 2021 - Present
The University of Tennessee Health Science Center (UTHSC)
Memphis, TN 38103
United States
Clinical Research Coordinator with an M.D. equivalent degree in Clinical Medicine and a robust background in biomedical research. Possesses diverse expertise in oncology, molecular biology, and DNA repair mechanisms, with substantial experience in both clinical and laboratory settings. Proficient in coordinating research projects, and data analysis, ensuring compliance with ethical and scientific standards.
Skilled in designing and conducting experiments using animal models to explore gene regulation, signaling pathways, and disease mechanisms in cancer and stem cell biology. Recognized for contributing to multiple high-impact publications that highlight the interplay of hormonal regulation, signaling pathways, and cancer progression.
Known for adaptability, attention to detail, and a commitment to advancing medical knowledge. Combines a strong foundation in clinical practice with a passion for laboratory research, excelling at bridging the gap between bench science and translational medicine. Eager to apply skills and collaborate with interdisciplinary teams to further innovation in biomedical research and patient care.
- Molecular Oncology
- Investigating the genetic and molecular mechanisms driving cancer development, progression, and resistance to therapies, with a particular focus on melanoma and hormone-related pathways.
- DNA Repair Mechanisms
- Exploring the role of sex hormones and their balance in modulating DNA repair pathways in human cells to uncover potential therapeutic targets.
- Gene Regulation
- Examining the interplay between transcription factors, signaling pathways, and genetic polymorphisms in regulating cellular processes such as bone mineralization and immune responses.
- Stem Cell Biology
- Studying mesenchymal stem cell differentiation and signaling pathways, including WNT signaling, and their implications in regenerative medicine and cancer biology.
- Translational Medicine
- Bridging laboratory findings and clinical applications to develop novel diagnostic and therapeutic approaches for cancer and other diseases.
- GATA4 Regulates Mesenchymal Stem Cells via Direct Transcriptional Regulation of the WNT Signalosome, Bone, December 23, 2020, DOI: 10.1016/j.bone.2020.115819
- Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in Osteoblasts, AJHG The American Journal of Human Genetics, in 2022, https://doi.org/10.1016/j.ajhg.2021.11.018
- GATA4 and estrogen receptor alpha bind at SNPs rs9921222 and rs10794639 to regulate AXIN1 expression in osteoblasts, Human Genetics, DOI: 10.1007/s00439-022-02463-8
- Tumor Androgen Receptor Protein Level is Positively Associated with a Better Overall Survival in Melanoma Patients Submitted to Genes, Genes, DOI: 10.3390/genes14020345
- Regulation and Function of FOXC1 in Osteoblasts, Journal of Developmental Biology, DOI: 10.3390/jdb11030038
- Tumor Androgen Receptor Protein Level Is Positively Associated with a Better Overall Survival in Melanoma Patients, https://doi.org/10.3390/genes14020345
- Unsupervised Analysis Reveals the Involvement of Key Immune Response Genes and the Matrisome in Resistance to BRAF and MEK Inhibitors in Melanoma, https://doi.org/10.3390/cancers16132313
- A retrospective single-institute study reveals a vertical gradient of the density of cutaneous melanoma from head to toe, https://doi.org/10.1002/ski2.463
- WNT5B drives osteosarcoma stemness, chemoresistance and metastasis, Clinical and Translational Medicine, DOI: https://doi.org/10.1002/ctm2.1670