Dr. Dina Ibrahim is a Postdoctoral Research Scientist at Washington University in St. Louis, working at the intersection of molecular immunology, immunometabolism, and oncology. She completed her Ph.D. in Immunology, Oncology, Inflammation, and Infectiology at the University of Limoges, France, where she characterized c-MYC transcript variants and epigenetic regulatory mechanisms in B-cell lymphoma. Her postdoctoral research spans two major programs: (1) the immunometabolic investigation of circulating fatty acid synthase (cFAS) in macrophage-driven atherosclerosis, NAFLD/NASH, and GLP-1 receptor agonist pharmacology; and (2) translational immuno-oncology using PET imaging to study PD-L1 glycosylation and Src-mediated immune checkpoint modulation in gastric cancer. Dr. Ibrahim has published in Nature – Communication Biology, Frontiers in Immunology, and Biomolecules, and has presented her work at international conferences including the American Heart Association Scientific Sessions, the World Molecular Imaging Congress, and the American College of Surgeons Clinical Congress. She also actively mentors undergraduate researchers and serves as a peer reviewer.

• Tumor immunology and immune checkpoint regulation (PD-L1 glycosylation, anti-PD-L1 immunotherapy)
• Immunometabolism in cancer and cardiovascular disease
• Molecular oncology: c-MYC regulation, B-cell lymphoma, epigenetics
• PET-based immunoimaging and theranostics
• GLP-1 receptor agonists and metabolic-immune crosstalk
• Macrophage biology, foam cell formation, and vascular inflammation

• Dina Ibrahim, Meade R, Engel C, Belaygorod L, Arif B, Hsu F-F, Adak S, Catlett R, Zhou M, Ilagan MXG, Semenkovich CF, Zayed MA. Targeting Fatty Acid Synthase Reduces Aortic Atherosclerosis and Inflammation. Nature – Communication Biology. 2025. https://doi.org/10.1038/s42003-025-07656-1
• Dina Ibrahim, Simó C, Brown EL, Shmuel S, Panikar SS, Benton A, DeWeerd R, Dehdashti F, Park H, Pereira PMR. PD-L1 has a heterogeneous and dynamic expression in gastric cancer with implications for immunoPET. Frontiers in Immunology. 2024. https://doi.org/10.3389/fimmu.2024.1405485
• Dina Ibrahim, Prévaud L, Faumont N, Troutaud D, Feuillard J, Diab-Assaf M, Oulmouden A. Alternative C-MYC mRNA Transcripts as an Additional Tool for c-Myc2 and c-MycS Production in BL60 Tumors. Biomolecules. 2022. https://doi.org/10.3390/biom12060836
• Shmuel S, Monette S, Ibrahim D, Pereira PMR — Dina Ibrahim (co-author). PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin. Molecular Imaging and Biology. 2024. https://doi.org/10.1007/s11307-024-01917-x
• Zaghloul MS, Elizondo-Benedetto S, Alrata L, Dina Ibrahim, Speller N, Koklu B, Arif B, Zayed MA. Protocol for dorsal ovariectomy and elastase-induced abdominal aortic aneurysm in rats. 2025. https://doi.org/10.1016/j.xpro.2025.104043

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