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Case Report | Open Access

Published on: 19 Feb 2026

Article ID: wjcds.2026.b1902

Hypoxic-Ischemic Colitis at Griffiths’ Point in a Term Infant with Hypoxic-Ischemic Encephalopathy and Acute Kidney Injury Requiring Emergency Subtotal Colectomy
Govani DR 1 Swamy KB 2 Mehta AR 3 Midha PK 4 Govani ND 1 Panchasara NG 1 Patel RR 1 Patel RV* 1

A term male neonate with moderate Hypoxic-Ischaemic Encephalopathy (HIE) developed persistent rectal bleeding and rising inflammatory markers during therapeutic hypothermia. Despite conservative management, he deteriorated with signs of colonic ischaemia. Imaging suggested segmental hypoperfusion centred at Griffiths’ point at the splenic flexure, a recognised colonic watershed zone. Emergency laparotomy revealed extensive non-viable colon requiring subtotal colectomy with end ileostomy.…

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