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Review Article | Open Access

Published on: 23 Apr 2026

Article ID: wjd.2026.d2302

Cutibacterium acnes and Acne Vulgaris: A Narrative Review of Epidemiology, Pathogenesis, Diagnosis, Management, and Future Perspectives
Malik Sallam* 1 Maya El Khoury 2 Kusuma Narayana 3 Razan Zahrawi 4 Mohammed Sallam 5

Background and Aims: Acne vulgaris is among the most prevalent inflammatory skin disorders worldwide and represents a substantial source of dermatologic morbidity and psychosocial distress, particularly among adolescents and young adults. This narrative review aimed to synthesize contemporary evidence on the epidemiology, molecular microbiology, pathogenesis, clinical diagnosis, management, prevention, and psychosocial burden of acne vulgaris, while also examining unresolved…

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Case Report | Open Access

Published on: 13 Apr 2026

Article ID: wjd.2026.d1306

Acquired Spiny Keratoderma in an Older Adult: Implications for Malignancy Surveillance and Longitudinal, Cost-Conscious Care
Danny Lee* 1 Julianna Gregory 2 Jenny Lee 3 Anna Marchus 2 Aymen Arain 4 Cassie Cummings 1

We present a case of a 72-year-old man with a 30-year history of palmar spiny keratoderma and prior unprovoked deep vein thrombosis. Lesions demonstrated partial improvement with topical keratolytics and retinoids, though treatment adherence was limited by medication cost, necessitating reliance on mechanical exfoliation and over-the-counter alternatives.

Spiny keratoderma is a rare skin disorder featuring small keratotic projections from the palms and may also affect the soles.…

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Research Article | Open Access

Published on: 23 Feb 2026

Article ID: wjd.2026.b2301

Demography, Incidence, Prevalence, and Comorbidities in Hidradenitis Suppurativa: Insights from a Large-Scale Database Analysis
Nima Karodeh 1 Jordan Young 1 Shanae' Henry 1 Ugonna Nwannunu 1 Gianna Haskin 1 Samrawit Zinabu 2 Akachukwu Eze 1 Isha Wilson 1 Destyni Hubbard 1 Zaria Franklin 1 Rawan Elkomi 2 Elizabeth Beyene 2 Mekdem Bisrat* 2 Miriam Michael 2,3

Background and Aims: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and draining tunnels in intertriginous regions. Despite extensive research since its description in 1854, the global prevalence remains highly variable (0.053%-4.1%), with notable disparities across demographic groups. This study examines demographic patterns and prevalence trends of HS in the United States to inform targeted public health…

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Letter to Editor | Open Access

Published on: 19 Feb 2026

Article ID: wjd.2026.b1903

Sleep Disturbance and Mental Health Burden of Prurigo Nodularis in Older Adults: Implications for Cognitive Decline and Delirium Risk
Marchus Anna* 1 Kermet Sophia 1 Rayaan Kader 1 Gregory Julianna 1 Danny Lee 2

Background: Prurigo nodularis (PN) is a chronic inflammatory dermatosis characterized by severe pruritus and nodular skin lesions and disproportionately affects older adults. Although PN is traditionally conceptualized as a dermatologic condition, its associated sleep disturbance and psychological burden may be particularly relevant in geriatric populations.

Objective: This review synthesizes existing evidence describing sleep disturbance,…

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Research Article | Open Access

Published on: 28 Jan 2026

Article ID: wjd.2026.a2803

Increased Risk of Adverse Cardiovascular Outcome in Psoriasis: A Retrospective Analysis Using a Large Database
Zinabu S 1 Hubbard D 1 Beyene E 1 Bisrat M* 1 Beyene M 1 Karodeh N 1 Henry S 1 Young J 1 Ugarte A 1 Sen A 1 Michael M 1

Background: Psoriasis, a chronic inflammatory skin condition, is linked to an increased risk of cardiovascular diseases due to shared inflammatory pathways. However, the direct impact of psoriasis on cardiovascular risk factors remains underexplored. This study investigates the relationship between psoriasis and cardiovascular events, including Myocardial Infarction (MI), stroke, heart failure, arrhythmias, and thromboembolic diseases.

Methods: A…

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Case Report | Open Access

Published on: 22 Jan 2026

Article ID: wjd.2026.a2201

Neonatal Epidermolysis Bullosa Simplex: Early Diagnostic Clarification and Multidisciplinary Management in a Term Female Infant
Govani DR 1 Mehta AR 2 Midha PK 3 Govani ND 1 Panchasara NG 1 Patel RR 1 Patel RV* 1

Epidermolysis bullosa (EB) comprises a heterogeneous group of inherited mechanobullous disorders characterised by skin fragility and blister formation following minimal trauma [1–3]. We report a female neonate presenting with localised blistering on the dorsum of the right foot and over the heel, ultimately diagnosed with epidermolysis bullosa simplex (EBS). Early multidisciplinary involvement, meticulous wound care, and parental counselling were central to management [8, 9]. This case…

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Mini Review | Open Access

Published on: 03 Jan 2026

Article ID: wjd.2026.a0302

Vaping and Dermatologic Manifestations: A Scoping Review
Julianna Gregory* 1 Abigail Watson 1 Dr. Jessica Houpe 1 Dr. Monica Constantinescu 1 Dr. Armand B. Cognetta 1

Background: The use of electronic cigarettes (ECs), or vaping, has been increasing at an alarming rate, constituting a significant public health concern. A lack of data regarding the impact of EC use on dermatologic disease requires a scoping review of the current literature.

Methods: Our scoping review protocol was registered on Open Science Framework. Two independent reviewers completed a systematic review of the literature in Web of Science,…

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Research Article | Open Access

Published on: 19 Mar 2025

Article ID: wjd.2025.c1901

Efficiently Curing Dyshidrosis
Dr. Xinghong Yang* 1

Dyshidrosis has traditionally been considered a chronic inflammatory skin disorder characterized by itchy, vesicular outbreaks on the palms, soles, and fingers, often proving resistant to standard medical interventions. Contemporary dermatology attributes its potential triggers to genetic predispositions, allergic reactions, and inflammatory processes, yet its underlying cause remains elusive. This study introduces an alternative perspective grounded in the principles of karma and the…

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