A Critical Review on Instrumental Methods of Chemical Analysis

Abstract

Instrumental methods of chemical analysis have revolutionized modern analytical science by providing rapid, precise, and highly sensitive techniques for qualitative and quantitative determination of chemical substances. Unlike traditional wet chemical methods, these techniques rely on physical and physicochemical properties such as light absorption, electrical potential, conductivity, and emission intensity to obtain accurate results. This review highlights the fundamental principles, working mechanisms, advantages, and applications of major instrumental techniques including pH metry, potentiometry, conductometry, spectrophotometry, flame photometry, and atomic absorption spectroscopy. Each method offers unique analytical capabilities suited to different scientific and industrial needs—from monitoring hydrogen ion concentration and ionic conductivity to determining metal ions and molecular absorption spectra. The integration of these methods has greatly enhanced the efficiency, reproducibility, and automation of chemical analysis, allowing detection of trace components at micro- and nanolevels. Technological innovations such as microprocessor control, digital data processing, and miniaturized sensors have further expanded their scope in research, environmental monitoring, pharmaceuticals, and materials science. The review concludes that instrumental analysis forms the cornerstone of modern chemistry, enabling precise characterization of substances and supporting continual advancements in science, technology, and industry

Keywords: Instrumental Analysis; Spectrophotometry; Potentiometry; Conductometry; Atomic Absorption Spectroscopy

Citation

Prasad NR, Powar AA, Gurav RP, Dodla SR, Kamble S, Vhankhande BB, et al. A Critical Review on Instrumental Methods of Chemical Analysis. WebLog J Anal Pharm Chem. wjapc.2025. k1401. https://doi.org/10.5281/zenodo.17685352