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ARTICLE TYPE : MINI REVIEW

Published on :   07 Feb 2026, Volume - 2
Journal Title :   WebLog Journal of Anatomy | WebLog J Anat
Source URL:   weblog iconhttps://weblogoa.com/articles/wjat.2026.b0711
Permanent Identifier (DOI) :  doi iconhttps://doi.org/10.5281/zenodo.18780254

Cancer as an Anatomical Disease

Ioanna Tsatsou 1 *
Dimitra Bartzi 2
1One Day Clinic, Oncology-Hematology Department, Hellenic Airforce General Hospital, Athens, Greece
2Oncology Department, Hellenic Airforce General Hospital, Athens, Greece

Abstract

Cancer is most commonly described as a molecular and genetic disorder driven by mutations that alter cell proliferation and survival. However, malignant transformation also represents an anatomical phenomenon characterized by progressive disruption of normal tissue architecture at cellular, histological, and organ levels. This brief review examines cancer from an anatomical perspective, emphasizing alterations in tissue organization, cellular morphology, stromal composition, vascular structure as well as anatomical pathways of invasion and metastasis. Viewing cancer as an anatomical disease highlights the enduring relevance of anatomical sciences in cancer research and clinical practice.

Keywords: Cancer; Anatomy; Histopathology; Tumor Microenvironment; Tissue Architecture; Oncology

Citation

Tsatsou I, Bartzi D. Cancer as an Anatomical Disease. WebLog J Anat. wjat.2026.b0711. https://doi.org/10.5281/zenodo.18780254
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