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Research Article | Open Access

Published on: 18 Sep 2026

Article ID: wjaa.2026.i1804

New Azo Amide Compounds Derived from Benzocaine Synthesis, Characterization, and Study of Biological Activity
Adeel Asghar* 1 Hussain Ali 1

Benzocaine (0.05 mol, 7.42 g) was decomposed in NaNO2 in the presence of HCl at temperatures ranging from 0 to 5 degrees Celsius to produce several novel derivatives of Azo compounds (50 mL). 2-Nitrophenol (80%, 7.5 mL) and compound 1 (0.05 mol, 10.67 g) were heated for two hours at reflux in 50 mL of ethanol. When the procedure was stopped, the mixture had cooled to a normal temperature. Filtered and water was used to clean the precipitate. The ethanol yield solidified. This reaction was…

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Case Presentation | Open Access

Published on: 07 Jul 2025

Article ID: wjaa.2025.g0701

A Herpesvirus Relapse, After a L-arginine Overload as a Possible Trigger, and the Therapeutic Use of Its Antagonist Competitor L-lysine: Brief Review and Case Report
Maria Cristina Pedrazini* 1,2 Victor Augusto Benedicto dos Santos 3 Thereza Cristina Pedrazini de Castilho 4 Francisco Carlos Groppo 5

Introduction: Arginine may be associated with the latent herpesvirus reactivation and L-lysine has been shown to inhibit certain viral replication phases by antagonizing arginine.

Case Presentation: Man with latent HHV-1 experienced work-related stress but only after an arginine overloud, an initial recurrent labial herpes was observed. A loading dose of L-lysine was prescribed that day, followed by a maintenance dose for 30 days. Arginine-rich…

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