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Case Presentation | Open Access

Published on: 07 Jul 2025

A Herpesvirus Relapse, After a L-arginine Overload as a Possible Trigger, and the Therapeutic Use of Its Antagonist Competitor L-lysine: Brief Review and Case Report
Maria Cristina Pedrazini * 1,2 Victor Augusto Benedicto dos Santos 3 Thereza Cristina Pedrazini de Castilho 4 Francisco Carlos Groppo 5

Introduction: Arginine may be associated with the latent herpesvirus reactivation and L-lysine has been shown to inhibit certain viral replication phases by antagonizing arginine.

Case Presentation: Man with latent HHV-1 experienced work-related stress but only after an arginine overloud, an initial recurrent labial herpes was observed. A loading dose of L-lysine was prescribed that day, followed by a maintenance dose for 30 days. Arginine-rich…

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