WebLog Journal of Gerontology and Geriatrics

This mini-review is devoted to evaluation of gerontologic advances approximately till the onset of current century, making some prognostic considerations for the next decades. An attention is focused on the works of some Russian authors, together with our own studies related to stress hormones and proteins.

Keywords: Aging; Gerontology; Glucocorticoids; Stress

This story began for us at the end of the decade of eighties when we became involved in studies on hormonal regulation in primary liver and pituitary cell cultures obtained from rats of different age groups: perinatal, prepubertal and adults. These studies continued later in vivo on somaitc and organ growth in rats treated with several hormones. The results of investigations in vivo and in vitro, together with the data of subsequent epidemiological studies have influenced our decision to be…

The connection between age-related dynamics and gender differences, as referred to morbidity and mortality, is outlined, suggesting the involvement of endocrine mechanisms in programming/ imprinting and embedding phenomena, including the contribution of glucocorticoids and sex steroid hormones.

Keywords: Gender Differences; Morbidity; Mortality; Ontogeny

The epidemiologic data are presented for morbidity and mortality from cardiometabolic disorders and Alzheimer disease during chronologic period 2008-2023 in three Brazilian states of Southern region. The evidence obtained suggests that senescent phase of human ontogeny can be subdivided due to peculiarities of age-related dynamics and gender differences in morbidity and mortality.

Keywords: Morbidity; Mortality; Ontogeny; Metabolic Syndrome; Dementia

The present short communication serves to justify important relations of phylo- and ontopathogenic models elaborated by us to the broadened versions of gerontology and endocrinology, culminating in our recently offered, more general concept of ontogenetic bioregulation.

Keywords: Conceptual Models; Ontogeny; Phylogeny

Armed conflicts, wars, and natural disasters frequently produce severe humanitarian crises that disproportionately affect vulnerable populations, particularly older adults. Despite the growing global elderly population and their heightened susceptibility to health deterioration, displacement, and social isolation during crises, leadership strategies addressing their specific needs remain insufficiently developed. This study examines the necessity of specialised leadership frameworks for…

Objectives: To synthesise current evidence on the epidemiology, risk factors, diagnostic strategies, and therapeutic approaches in osteoporosis, with emphasis on recent advances in risk stratification, imaging, and pharmacological management such as anabolic therapies, vitamin D analogues such as alfacalcidol, and emerging agents.

Design: Narrative review of contemporary literature, including recent clinical reviews and…

Background: Knee osteoarthritis (KOA) in geriatric populations presents a multifaceted challenge characterized by progressive cartilage degradation, sensorimotor dysfunction, and compromised joint stability. While pain management remains central to rehabilitation, proprioceptive dysfunction and impaired dynamic stability represent significant but understudied mechanisms in older adults with KOA. This randomized controlled trial investigates the efficacy of structured…

Background: Elderly patients are at higher risk of postoperative cognitive dysfunction (POCD), which may delay recovery. Inhalational agents, such as Sevoflurane and Desflurane, differ in their pharmacokinetic properties and may influence early cognitive outcomes.

Aim: To compare the effects of Desflurane and Sevoflurane on early recovery and short-term postoperative cognitive function in elderly patients undergoing elective surgery under general…