Introduction: Cushing’s syndrome (CS) during pregnancy is a rare and complex condition due to the overlap of symptoms with normal physiological changes during pregnancy and the associated maternal and fetal risks.

Objective: To describe three cases of Cushing’s syndrome diagnosed during or shortly after pregnancy, detailing clinical characteristics, diagnostics, management, and outcomes, alongside a review of recent…

Introduction: Oculomotor palsies are a rare manifestation of focal diabetic neuropathies. Their clinical presentation may mimic serious neurological conditions, making diagnosis challenging. Objective: To report a series of four cases of oculomotor palsy in diabetic patients and to analyze their clinical, diagnostic, therapeutic, and evolutionary characteristics in light of the literature.

Patients and Methods: A retrospective descriptive study…

Introduction: The association between type 1 diabetes (T1D) and epilepsy has been reported more frequently than in the general population. However, the exact pathophysiological link remains poorly understood.

Objective: To describe the clinical characteristics of patients presenting with an association of T1D and epilepsy and to discuss the possible pathophysiological mechanisms in light of data from the…

Background: Medial tibial stress syndrome (MTSS) affects 4-35% of runners with substantial recurrence rates ranging from 25-57% following standard care protocols. While individual interventions (load management, gait retraining, strengthening) demonstrate independent efficacy, high-quality randomized controlled trial evidence evaluating integrated models combining all three components remains limited in the current literature.

Objective: To…

Background: While gait retraining and neuromuscular strengthening demonstrate individual clinical efficacy in medial tibial stress syndrome (MTSS) management, the integrated biomechanical mechanisms through which combined intervention modifies lower limb loading parameters and tissue stress remains inadequately characterized in contemporary literature. High-resolution biomechanical quantification integrating three-dimensional motion capture, ground reaction force analysis,…

Introduction: Primary hyperparathyroidism (PHPT) is one of the most common endocrine disorders, characterized by inappropriate secretion of parathyroid hormone (PTH), leading to disturbances in calcium–phosphate metabolism and multisystem complications.

Objective: To determine the prevalence and profile of clinical, biological, and radiological complications of PHPT in a Moroccan hospital-based cohort.

Materials and…

Introduction: Celiac disease (CD) is an autoimmune enteropathy triggered by gluten ingestion in genetically predisposed individuals. It is frequently associated with type 1 diabetes (T1D), with a prevalence significantly higher than that observed in the general population. Diagnosis usually relies on positivity of specific autoantibodies and histological confirmation. However, seronegative forms can be observed, notably in T1D patients, making diagnosis more…

Introduction: Graves’ disease is an autoimmune disorder characterized by hyperthyroidism related to the presence of thyroid-stimulating hormone receptor antibodies. Long considered protective against thyroid cancer, it is now recognized as potentially associated with differentiated thyroid carcinomas, mainly papillary carcinoma.

Objective: To describe the clinical, histological, therapeutic, and outcome characteristics of thyroid carcinomas…

Background: Patient–ventilator asynchrony (PVA) is a common complication in mechanically ventilated patients, leading to increased morbidity, prolonged ventilation, and respiratory muscle fatigue. Early detection is critical. Artificial intelligence (AI) systems, including convolutional neural networks (CNNs) and machine learning algorithms, have been applied to automate detection.

Objective: To systematically review current evidence on AI-based…

Objectives: To re‑examine infantile hypertrophic pyloric stenosis (IHPS) through a contemporary, multidimensional framework that integrates structural, functional, and psycho‑neuro‑endocrine‑immune (PNEI) mechanisms. This review synthesises current evidence on IHPS epidemiology, pathophysiology, and clinical presentation, and evaluates minimally invasive diagnostic and therapeutic approaches. It further explores how emerging insights into gut–brain and neuroimmune regulation…