WebLog Journal of Endocrinology and Diabetes

Double diabetes refers to the coexistence, in the same patient, of immunological features of type 1 diabetes (T1D) and clinical and metabolic manifestations of type 2 diabetes (T2D), especially insulin resistance. This entity, still…

Introduction: Von Hippel–Lindau (VHL) disease is an autosomal dominant genetic disorder predisposing to the development of benign and malignant tumors, notably pheochromocytomas, which are often bilateral and of early…

Introduction: Testicular regression syndrome (TRS) is a rare cause of disorders of sex development in 46,XY individuals. It corresponds to the partial or complete disappearance of testicular tissue following initially normal male…

Introduction: Rathke’s cleft cyst (RCC) is a rare benign cystic lesion of the sellar region arising from an embryonic remnant of Rathke’s pouch. Although often asymptomatic, it may become responsible for endocrine, neurological,…

Introduction: Cushing’s syndrome (CS) during pregnancy is a rare and complex condition due to the overlap of symptoms with normal physiological changes during pregnancy and the associated maternal and fetal…

Introduction: Oculomotor palsies are a rare manifestation of focal diabetic neuropathies. Their clinical presentation may mimic serious neurological conditions, making diagnosis challenging. Objective: To report a series of four…

Introduction: The association between type 1 diabetes (T1D) and epilepsy has been reported more frequently than in the general population. However, the exact pathophysiological link remains poorly…

Introduction: Primary hyperparathyroidism (PHPT) is one of the most common endocrine disorders, characterized by inappropriate secretion of parathyroid hormone (PTH), leading to disturbances in calcium–phosphate metabolism and…

Introduction: Celiac disease (CD) is an autoimmune enteropathy triggered by gluten ingestion in genetically predisposed individuals. It is frequently associated with type 1 diabetes (T1D), with a prevalence significantly higher…

Introduction: Graves’ disease is an autoimmune disorder characterized by hyperthyroidism related to the presence of thyroid-stimulating hormone receptor antibodies. Long considered protective against thyroid cancer, it is now…

Turner syndrome (TS) is a rare chromosomal disorder characterized by partial or complete monosomy X. The presence of Y chromosome material, particularly the sex-determining region Y(SRY) gene, has important clinical implications due to the…

Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by inappropriate parathyroid hormone (PTH) secretion leading to chronic hypercalcemia. Acute pancreatitis is a rare but potentially severe complication of PHPT. We…

The synchronous occurrence of laryngeal squamous cell carcinoma (LSCC) and papillary thyroid carcinoma (PTC) is rare and is most often discovered incidentally on histopathological examination of surgical specimens. We report a series of four…

The association between primary hyperparathyroidism (PHPT) and non-medullary thyroid carcinoma is rare and is most often discovered incidentally during surgical exploration or histopathological examination. We report a case series of three…

Wolfram Syndrome (WS), also known as DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), is a rare neurodegenerative disorder [1, 2]. This condition features symptoms that typically appear progressively from childhood…

Introduction: Hungry Bone Syndrome (HBS) is a rare but potentially severe metabolic complication following parathyroidectomy, occurring mainly in patients with severe primary hyperparathyroidism (PHPT) and high bone turnover…

Introduction Maturity Onset Diabetes of the Young (MODY) is a heterogeneous group of monogenic diabetes characterized by a primary defect in insulin secretion. It is a rare form of diabetes caused by autosomal dominant mutations, usually…

Latent autoimmune diabetes in adults (LADA) is an autoimmune form of diabetes situated between classical type 1 diabetes (T1D) and type 2 diabetes (T2D). It typically affects older adults and progresses more slowly toward insulin dependence. We…

Introduction Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder caused by mutations in several genes involved in low-density lipoprotein (LDL) metabolism [1, 2]. It is characterized by an isolated…

Primary hyperparathyroidism corresponds to inappropriate overproduction of parathyroid hormone. It is a predominantly female disease and is often asymptomatic. Diagnosis is based solely on biological findings, and curative treatment is…

Nelson’s syndrome is a severe complication that may develop in patients with Cushing’s disease treated with bilateral adrenalectomy. Since pituitary tumors in Nelson’s syndrome are often aggressive, early diagnosis and careful management are…

Brown tumors are bone manifestations of hyperparathyroidism (HPT). They usually occur in severe forms accompanied by signs of periosteal bone resorption. Their treatment mainly relies on parathyroidectomy.

We report a series of 9…

Oncocytic thyroid carcinoma is a rare tumor characterized by the proliferation of Hürthle (oncocytic) cells. It is an aggressive tumor and is insensitive to radioiodine therapy. We report a series of five patients diagnosed with oncocytic…

Diabetic ketoacidosis (DKA) is a frequent complication that generally evolves favorably; however, thromboembolic complications may occur. Pulmonary embolism is a rare complication. We report a series of five cases of type 1 diabetic female…

Type 2 diabetes (T2D) is a global health burden traditionally regarded as a metabolic disorder driven by insulin resistance, genetics, and lifestyle factors. Although scientific research has made considerable progress in identifying molecular…

Type 2 diabetes (T2D) is a growing global health concern, characterized by insulin resistance, chronic hyperglycemia, and a range of associated complications. Traditional treatment regimens have largely focused on lifestyle changes and…