WebLog Journal of Endocrinology and Diabetes

Letter to the Editor

Type 2 diabetes mellitus represents a major public health issue, and its complications extend beyond the strictly metabolic and vascular domains. In older adults, type 2 diabetes is now recognized as a significant risk factor for cognitive impairment, encompassing not only vascular dementia but also Alzheimer’s disease and mixed forms of dementia [1].

Crohn’s Disease (CD) is a chronic inflammatory bowel disease primarily affecting the terminal ileum and colon. Graves’ Disease (GD) is an autoimmune thyroid disorder characterized by hyperthyroidism. The coexistence of these two autoimmune conditions is rare and raises important questions regarding their shared pathophysiological mechanisms and optimal management strategies.

Introduction

Ischemic strokes associated with pituitary adenomas are rare events, mostly reported in the context of pituitary apoplexy [1, 2]. We report a unique clinical case of a pituitary macroadenoma revealed by a pontine ischemic stroke.

Introduction

Acromegaly is a rare endocrine disorder caused by excessive secretion of Growth Hormone (GH), usually from a pituitary adenoma [1]. Hirsutism, a condition characterized by excessive terminal hair growth in a male pattern in women, has been occasionally reported as a cutaneous manifestation of acromegaly but is rarely the presenting symptom [2, 3]. We report a rare case of acromegaly revealed by hirsutism.

Double diabetes refers to the coexistence, in the same patient, of immunological features of type 1 diabetes (T1D) and clinical and metabolic manifestations of type 2 diabetes (T2D), especially insulin resistance. This entity, still insufficiently recognized, poses diagnostic and therapeutic challenges, particularly in adults. We report a series of three cases of double diabetes in adult female patients, illustrating the clinical heterogeneity of this condition, and discuss the…

Introduction: Von Hippel–Lindau (VHL) disease is an autosomal dominant genetic disorder predisposing to the development of benign and malignant tumors, notably pheochromocytomas, which are often bilateral and of early onset.

Objective: To describe the clinical, biological, radiological, and evolutionary characteristics of patients with bilateral pheochromocytomas associated with VHL disease and to compare our results with the literature…

Introduction: Testicular regression syndrome (TRS) is a rare cause of disorders of sex development in 46,XY individuals. It corresponds to the partial or complete disappearance of testicular tissue following initially normal male differentiation.

Objective: To describe the clinical, biological, radiological, and evolutionary characteristics of a series of 7 patients followed for TRS, and to compare them with recent literature…

Introduction: Rathke’s cleft cyst (RCC) is a rare benign cystic lesion of the sellar region arising from an embryonic remnant of Rathke’s pouch. Although often asymptomatic, it may become responsible for endocrine, neurological, or ophthalmological manifestations when it is large or compressive.

Objective: To describe the clinical, hormonal, radiological, therapeutic, and evolutionary characteristics of symptomatic Rathke’s cleft cysts through a…

Introduction: Cushing’s syndrome (CS) during pregnancy is a rare and complex condition due to the overlap of symptoms with normal physiological changes during pregnancy and the associated maternal and fetal risks.

Objective: To describe three cases of Cushing’s syndrome diagnosed during or shortly after pregnancy, detailing clinical characteristics, diagnostics, management, and outcomes, alongside a review of recent…

Introduction: Oculomotor palsies are a rare manifestation of focal diabetic neuropathies. Their clinical presentation may mimic serious neurological conditions, making diagnosis challenging. Objective: To report a series of four cases of oculomotor palsy in diabetic patients and to analyze their clinical, diagnostic, therapeutic, and evolutionary characteristics in light of the literature.

Patients and Methods: A retrospective descriptive study…