WebLog Journal of Endocrinology and Diabetes

Recurrent miscarriages are a rare occurrence in routine medical practice (1-3% of pregnancies) and represent a significant diagnostic challenge.

Subclinical hypothyroidism (SCH) is the most common thyroid disorder during pregnancy (3-5% of pregnant women) and can be responsible for several obstetric complications such as miscarriage, preterm birth, gestational hypertension, preeclampsia, and increased perinatal mortality. SCH remains an exceptional and still controversial cause…

Introduction: Primary Hyperparathyroidism (PHPT) is frequently associated with vitamin D deficiency, which may exacerbate hyperparathyroidism, hypercalcemia, and bone complications.

Objective: To assess vitamin D status in patients with PHPT and analyze its biological and clinical impact.

Patients and Methods: A retrospective study conducted over seven years (2015-2022) including patients hospitalized for PHPT. Serum…

Introduction: Multiple Endocrine Neoplasia type 2A (MEN2A) is a rare genetic disorder primarily characterized by Medullary Thyroid Carcinoma (MTC) and Primary Hyperparathyroidism (PHPT) in 20 to 30% of cases. PHPT is rarely the initial presenting symptom. This study aims to describe the clinical and biological features of PHPT in MEN2A to improve understanding and management of this condition.

Patients and Methods: This is a retrospective…

Ectopic mediastinal parathyroid adenoma is a significant cause of refractory and recurrent primary hyperparathyroidism. Although rare compared to cervical locations, this pathology presents particular diagnostic and therapeutic challenges. We report a series of three cases illustrating these difficulties, along with favorable outcomes achieved through advanced imaging and appropriate surgical management. An updated literature review is provided to better understand the optimal care for these…

Cowden syndrome is a rare genetic disorder, often linked to PTEN gene mutations, characterized by a predisposition to various cancers. We report the case of a patient presenting with papillary thyroid carcinoma revealing the syndrome, highlighting the importance of early diagnosis and multidisciplinary management.

Autoimmune Pancreatitis (AIP) is a rare cause of chronic pancreatitis, accounting for approximately 2% of cases [1]. The association between Slowly Progressive Type 1 Diabetes (SPT1D) and AIP is poorly described in the literature [2]. We report the case of a patient presenting with concomitant AIP and type 1 diabetes, highlighting the possible involvement of a common autoimmune process affecting both the endocrine and exocrine pancreatic functions.

Letter to the Editor

Type 2 diabetes mellitus represents a major public health issue, and its complications extend beyond the strictly metabolic and vascular domains. In older adults, type 2 diabetes is now recognized as a significant risk factor for cognitive impairment, encompassing not only vascular dementia but also Alzheimer’s disease and mixed forms of dementia [1].

Crohn’s Disease (CD) is a chronic inflammatory bowel disease primarily affecting the terminal ileum and colon. Graves’ Disease (GD) is an autoimmune thyroid disorder characterized by hyperthyroidism. The coexistence of these two autoimmune conditions is rare and raises important questions regarding their shared pathophysiological mechanisms and optimal management strategies.

Introduction

Ischemic strokes associated with pituitary adenomas are rare events, mostly reported in the context of pituitary apoplexy [1, 2]. We report a unique clinical case of a pituitary macroadenoma revealed by a pontine ischemic stroke.

Introduction

Acromegaly is a rare endocrine disorder caused by excessive secretion of Growth Hormone (GH), usually from a pituitary adenoma [1]. Hirsutism, a condition characterized by excessive terminal hair growth in a male pattern in women, has been occasionally reported as a cutaneous manifestation of acromegaly but is rarely the presenting symptom [2, 3]. We report a rare case of acromegaly revealed by hirsutism.