Dear Editor, We read with great interest the recently published article by Muthu and Nisarudeen titled “Correlation Between Core Muscle Endurance and Dynamic Balance in Silambam Practitioners” [1]. The authors should be applauded for addressing an important and relevant topic in sports physiotherapy, particularly within traditional martial arts. However, we would like to highlight several methodological and statistical aspects that require clarification to improve the validity and clinical…

Oral squamous cell carcinoma (OSCC) is one of the commonest cancers globally. Prevalence of the disease is high in the third world countries of South-east Asia, specifically tied to inherent abuse of tobacco and areca nuts. The disease manifests as oral potentially malignant disorders, such as OED, OSMF, leukoplakias, etc., that provides avenues for effective control early in the sequence of cancer progression and immune evasion. Focus of our study was to gather insights on the potential of…

Cycling requires high endurance, muscular strength, and cardiovascular fitness. This study examines the specific features of rehabilitation methods in cycling sports, focusing on individualized programs, lower limb therapy, gradual load progression, active recovery, physiotherapy interventions, and biomechanical corrections. The findings highlight the importance of a comprehensive, targeted approach to accelerate recovery, prevent injuries, and enhance athletic performance.

Armed conflicts, wars, and natural disasters frequently produce severe humanitarian crises that disproportionately affect vulnerable populations, particularly older adults. Despite the growing global elderly population and their heightened susceptibility to health deterioration, displacement, and social isolation during crises, leadership strategies addressing their specific needs remain insufficiently developed. This study examines the necessity of specialised leadership frameworks for…

Background: Immunotherapy in un-resectable stage III NSCLC shows delayed treatment effects and time-varying hazards that challenge proportional-hazards assumptions. We developed a Continuous-Time Markov Chain (CTMC) model - with piecewise hazards - to capture the temporal dynamics of durvalumab after chemoradiotherapy (PACIFIC era), enabling transparent extrapolation beyond early trial landmarks.

Methods: We specified a multi-state CTMC with…

Background and Aims: Acne vulgaris is among the most prevalent inflammatory skin disorders worldwide and represents a substantial source of dermatologic morbidity and psychosocial distress, particularly among adolescents and young adults. This narrative review aimed to synthesize contemporary evidence on the epidemiology, molecular microbiology, pathogenesis, clinical diagnosis, management, prevention, and psychosocial burden of acne vulgaris, while also examining unresolved…

The credibility of science and the advancement of knowledge depend on scholarly publishing's integrity. Trust is the foundation of the whole publication process, from data collection and article drafting to peer review and editorial decision-making. However, a number of integrity issues threaten the validity of academic writing in many emerging research systems, including Nigeria. The main categories of misbehavior in journal publication are thoroughly examined in this work, including…

Six years after the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) as a global pandemic, several key scientific and policy questions remain unresolved— an unsettling state of affairs given the inevitability of future pandemics. This Perspective examines five domains in which progress toward durable pandemic preparedness has stalled—not for lack of scientific innovation, but owing to fragmented data sharing, uneven translation of evidence into policy, and the…

Endometrial receptivity plays a key role in successful embryo implantation and is regulated by a combination of genetic and epigenetic mechanisms. This review aims to provide an overview of these regulatory processes and to highlight their relevance in clinical practice. In addition, current genomics-based diagnostic methods and emerging artificial intelligence-assisted approaches are discussed in relation to their potential use in evaluating endometrial receptivity. A literature review was…

Telemetry data that reflects the operational condition of onboard subsystems is continuously produced in vast quantities by satellite systems [1, 5]. For ensuring satellite reliability and preventing system failures, it is necessary to identify unusual trends in this data. Telemetry signals are frequently difficult for conventional anomaly detection techniques to handle because of their complicated temporal and multidimensional character. This study suggests a multimodal deep learning…