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Research Article | Open Access
Published on : 03 Jan 2026
Environmental and Laboratorial Investigation of Two Potential Spotted-fever Group Rickettsioses Cases in a Non-endemic Area of Brazil
Objective: To describe two-rickettsiosis laboratory-positive cases, and their eco-epidemiology, in non-autochthonous area of Brazil, 2022.
Methods: Case report study with environmental investigation, from May 1st to November 14th, 2022. Data collection occurred through interviews and health records; ectoparasites and dogs’ blood samples were collected, and spatial monitoring of a Rickettsia serologic reagent dog was performed. Software used: Epi…
DOI: 10.5281/zenodo.18212574 »
Mini Review | Open Access
Published on : 03 Jan 2026
Vaping and Dermatologic Manifestations: A Scoping Review
Background: The use of electronic cigarettes (ECs), or vaping, has been increasing at an alarming rate, constituting a significant public health concern. A lack of data regarding the impact of EC use on dermatologic disease requires a scoping review of the current literature.
Methods: Our scoping review protocol was registered on Open Science Framework. Two independent reviewers completed a systematic review of the literature in Web of Science,…
DOI: 10.5281/zenodo.18212823 »
Case Report | Open Access
Published on : 03 Jan 2026
Case Report: Neonatal Biliary Ascites Successfully Managed with Ultrasound‑Guided Peritoneal Drainage
Neonatal biliary ascites is a rare but important cause of progressive abdominal distension in early infancy. Diagnosis is often delayed because jaundice may be mild and stool color may remain normal. We report a term neonate presenting with increasing abdominal distention simulating bowel obstruction and respiratory compromise secondary to massive biliary ascites. Ultrasound demonstrated large-volume free fluid without biliary duct dilatation. Diagnostic paracentesis confirmed bile-stained…
DOI: 10.5281/zenodo.18212957 »
Review Article | Open Access
Published on : 03 Jan 2026
Integrating Soul Faculties with the Psycho‑Neuro‑Endocrine‑Immune Axis for Gut‑Focused Interventions: Implications for Metabolic Chaos and the Obesity Epidemic: A Narrative Review
Objective: To examine and explore how soul faculties can be integrated with the psycho‑neuro‑endocrine‑immune (PNEI) axis in gut‑focused interventions to address metabolic dysregulation and obesity, synthesizing evidence from psychosomatic medicine, neurogastroenterology, psychoneuroimmunology, and integrative health and to achieve the long awaited integrated unified concept between medicine, psychology, philosophy and theology.
Design: Narrative…
DOI: 10.5281/zenodo.18213073 »
Case Presentation | Open Access
Published on : 03 Jan 2026
Amlodipine: Guardian or Provocateur? Exploring Its Role in Parkinsonism
Drug-induced parkinsonism (DIP) is a debilitating side effect associated with several classes of medications. Amlodipine is a widely used dihydropyridine calcium channel blocker (CCB) commonly prescribed for hypertension and angina. We present a case of a 62-year-old man who underwent liver transplantation and developed parkinsonism shortly after initiation of amlodipine for hypertension. After ruling out other causes for his neurological presentation, discontinuation of amlodipine resulted…
DOI: 10.5281/zenodo.18213203 »
Research Article | Open Access
Published on : 03 Jan 2026
Technology-Driven Lifestyle Disorders: Long Term Musculoskeletal, Biomechanical, and Postural Consequences of Smartphone, AI, and Work-From-Home Device Usage in Young and Working-Age Adults—A Preventive and Interventional Study
The rapid proliferation of smartphone and digital device usage among young and working age adults has created a silent epidemic of technology-driven musculoskeletal disorders (tech MSDs), yet preventive interventions remain underexplored in clinical practice. This prospective, longitudinal cohort study combined with a randomized controlled trial (RCT) investigates the biomechanical consequences of technology-driven postural dysfunction and evaluates the efficacy of physiotherapy-led…
DOI: 10.5281/zenodo.18213348 »
Case Report | Open Access
Published on : 01 Jan 2026
Neonatal Hypoganglionosis Presenting as Acute Appendicitis in a 3‑year‑old Girl: A Case Report
Neonatal hypoganglionosis is a rare congenital dysganglionosis typically presenting in the neonatal period with intestinal obstruction. Initial symptoms may include intermittent massive abdominal distension and non-bilious vomiting. Presentation beyond infancy is common, often subtle and easily missed, while acute appendicitis following inadequate conservative therapy is exceptionally rare. We describe a 3-year-old girl who presented with atypical features of acute appendicitis, posing a…
DOI: 10.5281/zenodo.18204117 »
Case Presentation | Open Access
Published on : 01 Jan 2026
‘Schanz Pin Extractor’ Technique for Removal of a Broken Intramedullary Nail
Intramedullary nail removal is an uncommon but complicated procedure with significant surgical challenges, especially in the case of a broken nail. There are multiple cumbersome techniques for nail removal described that are frought with difficulty. We present a technique designed to take advantage of the difference in metallurgy of a stainless steel Schanz pin and a cannulated titanium intramedullary nail. We use a 5.0 mm self-tapping Schanz pin that is able to be drilled into the softer…
DOI: 10.5281/zenodo.18211400 »
Systematic Review | Open Access
Published on : 01 Jan 2026
Manual and Robotic Assisted Total Hip Arthroplasty: An Analysis of Peri-operative and Post-Operative Complications
Introduction: Robotic-assisted total hip arthroplasty usage has been rising among surgeons. This study aims to compare the difference between manual versus robotic-assisted total hip arthroplasty (RA-THA) short-term peri-operative and post-operative complications. Given improved acetabular component placement, we hypothesize that RA-THA is associated with the risk of lower overall complications and fewer revision surgical interventions compared to…
DOI: 10.5281/zenodo.18211524 »
Case Report | Open Access
Published on : 01 Jan 2026
Scarless Trans‑Umbilical Wedge Resection of a Prolapsed Vitellointestinal Duct Under Rectus Sheath Local Anesthesia Block in an Infant: A Case Report
This manuscript describes a rare and clinically significant case of a prolapsed vitellointestinal duct (VID) in a 6‑week old‑old infant, successfully managed using a scarless trans‑umbilical wedge resection performed entirely under local anesthesia. While VID anomalies are well documented, the use of a minimally invasive, awake surgical approach in an infant is exceptionally uncommon. Our report highlights a safe and effective alternative to general anesthesia in selected infants, a…
DOI: 10.5281/zenodo.18211587 »