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Published on :   03 Jan 2026

Environmental and Laboratorial Investigation of Two Potential Spotted-fever Group Rickettsioses Cases in a Non-endemic Area of Brazil

Ana Paula Betaressi da Silva 1 * Carolina de Castro Araújo Pacheco 1 Ana Carolina Mota de Faria 2 Ana Beatriz Pais Borsoi 3 Karla Bitencourth 3 Clarício Alvim Bugarim Neto 4 Waldinéa Maria da Silva 4 Diego Pereira Gonçalo Hora 4 Carlos Eduardo da Silva 4 Anderson Brandão Leite 5 Ana Íris de Lima Duré 6 Francisco Carlos Lins da Silva 7 Edivânia Izabel Santos Cavalcante Soares 7 Maria Jose da Silva Oliveira 7 Rodrigo Nogueira Angerami 8 Danielle Cristine Castanha da Silva 1 Luciana Nogueira de Almeida Guimarães 1 Luis Antonio Alvarado Cabrera 1 Gilberto Salles Gazêta 3

Objective: To describe two-rickettsiosis laboratory-positive cases, and their eco-epidemiology, in non-autochthonous area of Brazil, 2022.

Methods: Case report study with environmental investigation, from May 1st to November 14th, 2022. Data collection occurred through interviews and health records; ectoparasites and dogs’ blood samples were collected, and spatial monitoring of a Rickettsia serologic reagent dog was performed. Software used: Epi…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18212574 »

Mini Review | Open Access

Published on :   03 Jan 2026

Vaping and Dermatologic Manifestations: A Scoping Review

Julianna Gregory 1 * Abigail Watson 1 Dr. Jessica Houpe 1 Dr. Monica Constantinescu 1 Dr. Armand B. Cognetta 1

Background: The use of electronic cigarettes (ECs), or vaping, has been increasing at an alarming rate, constituting a significant public health concern. A lack of data regarding the impact of EC use on dermatologic disease requires a scoping review of the current literature.

Methods: Our scoping review protocol was registered on Open Science Framework. Two independent reviewers completed a systematic review of the literature in Web of Science,…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18212823 »

Case Report | Open Access

Published on :   03 Jan 2026

Case Report: Neonatal Biliary Ascites Successfully Managed with Ultrasound‑Guided Peritoneal Drainage

Govani DR 1 Mehta AR 2 Midha PK 3 Govani ND 1 Panchasara NG 1 Patel RR 1 Patel RV 1 *

Neonatal biliary ascites is a rare but important cause of progressive abdominal distension in early infancy. Diagnosis is often delayed because jaundice may be mild and stool color may remain normal. We report a term neonate presenting with increasing abdominal distention simulating bowel obstruction and respiratory compromise secondary to massive biliary ascites. Ultrasound demonstrated large-volume free fluid without biliary duct dilatation. Diagnostic paracentesis confirmed bile-stained…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18212957 »

Published on :   03 Jan 2026

Integrating Soul Faculties with the Psycho‑Neuro‑Endocrine‑Immune Axis for Gut‑Focused Interventions: Implications for Metabolic Chaos and the Obesity Epidemic: A Narrative Review

Zaparackaite I 1 Govani ND 2 Singh H 3 Singh SJ 4 Mehta AR 5 Midha PK 5 Patel R 2 Patel RV 2 *

Objective: To examine and explore how soul faculties can be integrated with the psycho‑neuro‑endocrine‑immune (PNEI) axis in gut‑focused interventions to address metabolic dysregulation and obesity, synthesizing evidence from psychosomatic medicine, neurogastroenterology, psychoneuroimmunology, and integrative health and to achieve the long awaited integrated unified concept between medicine, psychology, philosophy and theology.

Design: Narrative…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18213073 »

Case Presentation | Open Access

Published on :   03 Jan 2026

Amlodipine: Guardian or Provocateur? Exploring Its Role in Parkinsonism

Vansh Gulati 2 Elizabeth Beyene 1 Leon Seymour 2 Samrawit Zinabu 1 Ayushi Sen 2 Martin Borissov 3 Syed Fahad Gillan 1 Girma Ayale 1 Mekdem Bisrat 1 * Miriam Michael 1,3

Drug-induced parkinsonism (DIP) is a debilitating side effect associated with several classes of medications. Amlodipine is a widely used dihydropyridine calcium channel blocker (CCB) commonly prescribed for hypertension and angina. We present a case of a 62-year-old man who underwent liver transplantation and developed parkinsonism shortly after initiation of amlodipine for hypertension. After ruling out other causes for his neurological presentation, discontinuation of amlodipine resulted…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18213203 »

Published on :   03 Jan 2026

Technology-Driven Lifestyle Disorders: Long Term Musculoskeletal, Biomechanical, and Postural Consequences of Smartphone, AI, and Work-From-Home Device Usage in Young and Working-Age Adults—A Preventive and Interventional Study

P. Muthukrishnan 1 * Dr. Raja Durai 2

The rapid proliferation of smartphone and digital device usage among young and working age adults has created a silent epidemic of technology-driven musculoskeletal disorders (tech MSDs), yet preventive interventions remain underexplored in clinical practice. This prospective, longitudinal cohort study combined with a randomized controlled trial (RCT) investigates the biomechanical consequences of technology-driven postural dysfunction and evaluates the efficacy of physiotherapy-led…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18213348 »

Published on :   01 Jan 2026

Neonatal Hypoganglionosis Presenting as Acute Appendicitis in a 3‑year‑old Girl: A Case Report

Govani DR 1 Mehta AR 2 Midha PK 3 Govani ND 1 Panchasara NG 1 Patel RR 1 Patel RV 1 *

Neonatal hypoganglionosis is a rare congenital dysganglionosis typically presenting in the neonatal period with intestinal obstruction. Initial symptoms may include intermittent massive abdominal distension and non-bilious vomiting. Presentation beyond infancy is common, often subtle and easily missed, while acute appendicitis following inadequate conservative therapy is exceptionally rare. We describe a 3-year-old girl who presented with atypical features of acute appendicitis, posing a…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18204117 »

Case Presentation | Open Access

Published on :   01 Jan 2026

‘Schanz Pin Extractor’ Technique for Removal of a Broken Intramedullary Nail

Austin Kloc 1 * Emmanuele Santolini 2 Lamberto Felli 2 Daniel S. Horwitz 1

Intramedullary nail removal is an uncommon but complicated procedure with significant surgical challenges, especially in the case of a broken nail. There are multiple cumbersome techniques for nail removal described that are frought with difficulty. We present a technique designed to take advantage of the difference in metallurgy of a stainless steel Schanz pin and a cannulated titanium intramedullary nail. We use a 5.0 mm self-tapping Schanz pin that is able to be drilled into the softer…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18211400 »

Systematic Review | Open Access

Published on :   01 Jan 2026

Manual and Robotic Assisted Total Hip Arthroplasty: An Analysis of Peri-operative and Post-Operative Complications

Kloc A 1 * Ferrante S 1 Ozdag Y 1 Patil S 1

Introduction: Robotic-assisted total hip arthroplasty usage has been rising among surgeons. This study aims to compare the difference between manual versus robotic-assisted total hip arthroplasty (RA-THA) short-term peri-operative and post-operative complications. Given improved acetabular component placement, we hypothesize that RA-THA is associated with the risk of lower overall complications and fewer revision surgical interventions compared to…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18211524 »

Case Report | Open Access

Published on :   01 Jan 2026

Scarless Trans‑Umbilical Wedge Resection of a Prolapsed Vitellointestinal Duct Under Rectus Sheath Local Anesthesia Block in an Infant: A Case Report

Govani DR 1 Mehta AR 2 Midha PK 3 Govani ND 1 Panchasara NG 1 Patel RR 1 Patel RV 1 *

This manuscript describes a rare and clinically significant case of a prolapsed vitellointestinal duct (VID) in a 6‑week old‑old infant, successfully managed using a scarless trans‑umbilical wedge resection performed entirely under local anesthesia. While VID anomalies are well documented, the use of a minimally invasive, awake surgical approach in an infant is exceptionally uncommon. Our report highlights a safe and effective alternative to general anesthesia in selected infants, a…

Abstract » Full text PDF » Download PDF » doi iconDOI: 10.5281/zenodo.18211587 »